Tag: M.W=100-150

Nivoliers, F.; Decormeille, A.; Godard, A.; Queguiner, G. published the artcile< 6H-indolo[3,2-b]naphthyridines. Aza-analogs of ellipticine>, Reference of 55279-29-3, the main research area is indolonaphthyridine; cyclocondensation indole aminopyridinecarboxaldehyde.

The indolonaphthyridines I (X = N, X1 = X2 = CH; X = X2 = CH, X1 = N; X = X1 = CH, X2 = N) were prepared by cyclocondensation of the indole II with the corresponding pyridines. E.g., II reacted with 1 mol equiv 3-aminopyridine-2-carboxaldehyde in MeOH/KOH at room temperature for 3 days gave I (X = N, X1 = X2 = CH). Quaternization of I with MeI occurred at the terminal pyridine ring.

Tetrahedron Letters published new progress about Cyclocondensation reaction. 55279-29-3 belongs to class pyridine-derivatives, and the molecular formula is C6H6N2O, Reference of 55279-29-3.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Gu, Tingting; Kwaku Attatsi, Isaac; Zhu, Weihua; Li, Minzhi; Ndur, Samuel A.; Liang, Xu published the artcile< Enhanced electrocatalytic hydrogen evolutions of Co(II)phthalocyanine through axially coordinated pyridine-pyrene>, HPLC of Formula: 3731-53-1, the main research area is cobalt phthalocyanine immobilized multiwalled carbon nanotube electrocatalytic hydrogen evolution.

Non-precious metal catalysts can effectively evolve hydrogen in aqueous media, but a highly efficient metal-based catalyst is still a significant assignment. Herein, Co(II)phthalocyanine was noncovalently immobilized on multiwalled carbon nanotubes through axial coordination via pyridine-pyrene linker and applied towards hydrogen evolution reactions. This material provided a superiorly enhanced electrocatalyzed performance signifying high efficiency. With this behavior, our target material we believe paves the way towards designing efficient energy production and storage devices.

Inorganica Chimica Acta published new progress about Carbon nanotubes (multiwalled). 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, HPLC of Formula: 3731-53-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kiss, Levente; Pop, Alexandra; Shova, Sergiu; Rat, Ciprian I.; Silvestru, Cristian published the artcile< Synthesis and characterization of [4-{(CH2O)2CH}C6H4]2Hg, [4-(O:CH)C6H4]2Hg and [(E)-4-(RN:CH)C6H4]2Hg (R = 2'-py, 4'-py, 2'-pyCH2, 4'-pyCH2)>, Synthetic Route of 3731-53-1, the main research area is crystal structure mol mercury diaryl compound supramol preparation homocoupling.

The reaction of 4-[(CH2O)2CH]C6H4Br (1) with n-BuLi, followed by addition of HgCl2 to the in situ formed organolithium derivative, affords [4-{(CH2O)2CH}C6H4]2Hg (2). Deprotection of the formyl groups of 2 in presence of p-TsOH (p-Ts = 4-MeC6H4SO3) leads to [4-(O:CH)C6H4]2Hg (3). Condensation reactions of 3 with 2-aminopyridine (2-pyNH2), 4-aminopyridine (4-pyNH2), 2-aminomethylpyridine (2-pyCH2NH2), and 4-aminomethylpyridine (4-pyCH2NH2), in CH2Cl2, affords the novel diorganomercury(II) compounds of type [(E)-4-(RN:C)C6H4]2Hg [R = 2′-py (4), 4′-py (5), 2′-pyCH2- (6), 4′-pyCH2 (7)]. Compounds 2 and 3 were useful precursors for the preparation of the corresponding homocoupling products [4-{(CH2O)2CH}C6H4]2 (8) and [4-(O:CH)C6H4]2 (9) in presence of catalytic amounts of palladium(II) acetate. Compounds 2-9 were characterized by multinuclear magnetic resonance (NMR) (1H, 13C{1H}, and 199Hg{1H}, when appropriate) and IR (IR) spectroscopy and by mass spectrometry. The mol. structures of 3, 5, 6, 8, and 9 were determined by single-crystal X-ray diffraction.

Applied Organometallic Chemistry published new progress about Condensation reaction. 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Synthetic Route of 3731-53-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ghorbani, Zeynab; Abdollahifar, Mohammad Amin; Vakili, Kimia; Moghaddam, Meysam Hassani; Mehdizadeh, Mehdi; Marzban, Hassan; Rasoolijazi, Homa; Aliaghaei, Abbas published the artcile< Melittin administration ameliorates motor function, prevents apoptotic cell death and protects Purkinje neurons in the rat model of cerebellar ataxia induced by 3-Acetylpyridine>, Formula: C7H7NO, the main research area is acetylpyridine melittin CA motor apoptotic cell death Purkinje neuron; Cerebellar ataxia; Inflammation; Melittin; Motor skills; Neuroprotection.

Cerebellar ataxia (CA) is a condition in which cerebellar dysfunction leads to movement disorders such as dysmetria, asynergy and dysdiadochokinesia. This study investigates the therapeutic effects of Melittin (MEL) on 3-acetylpyridine-induced (3-AP) cerebellar ataxia (CA) rat model. Initially, CA rat models were generated by 3-AP administration followed by the i.p. injection of MEL. Then, motor performance and electromyog. (EMG) activity were assessed. Afterwards, the pro-inflammatory cytokines were analyzed in the cerebellar tissue. Moreover, the anti-apoptotic role of MEL in CA and its relationship with the protection of Purkinje cells were explored. The findings showed that the administration of MEL in a 3-AP model of ataxia improved motor coordination (P < 0.001) and neuro-muscular activity (p < 0.05), prevented the cerebellar volume loss (P < 0.01), reduced the level of inflammatory cytokines (p < 0.05) and thwarted the degeneration of Purkinje cells against 3-AP toxicity (P < 0.001). Overall, the findings imply that the MEL attenuates the 3-AP-induced inflammatory response. As such, it could be used as a treatment option for CA due to its anti-inflammatory effects. Toxicon published new progress about Animal tissue. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Formula: C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Tong, Xiaogang; Shi, Bingfei; Liu, Qian; Huo, Yanman; Xia, Chengfeng published the artcile< Retro-biosynthetic construction of corynanthe alkaloid skeletons from rhynchophylline alkaloids>, Quality Control of 93-60-7, the main research area is retro biosynthetic Wagner Meerwein rearrangement rhynchophylline corynanthe alkaloid.

Rhynchophylline alkaloids are bio-synthesized from corynanthe alkaloids via an oxidative rearrangement. We demonstrate here that corynanthe alkaloids could be generated from rhynchophylline alkaloids in a retro-biosynthetic manner via a Wagner-Meerwein rearrangement [e.g., I → II (85%) in presence of TFA in DCM]. A series of corynanthe analogs were afforded with good functional group tolerance and satisfactory yields.

Organic & Biomolecular Chemistry published new progress about Biomimetic synthesis (retro-biomimetic). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Quality Control of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wu, Wen Xin; Liu, Hu Cheng; Jin, Wei Jun published the artcile< Halogen Bonding Adsorbent Pyridine N-oxides for Iodine Capture in Water>, Recommanded Product: 2-Mercaptopyridinen-oxide sodiumsalt, the main research area is anthracene naphthaline pyridine oxide adsorbent single crystal surface structure; SC-SC transformation; halogen bonds; iodine capture; nonporous materials; pyridine N-oxide.

Rapid capture of 129I with high volatility and toxicity in the environment has attracted much attention. Herein we reported a firstly synthesized nonporous material: pyridine N-oxides (NTPO and ATPO) as iodine adsorbent. Both of NTPO and ATPO exhibit remarkable performance on the adsorption of iodine in aqueous solution, vapor state and organic solvents. Upon the capture of iodine, pyridine N-oxides were transformed to binary cocrystals combined with the pyridine N-oxides and iodine which is driven by halogen bond between iodine and oxygen atoms. Moreover, pyridine N-oxides shows high chem., thermal and moisture stability.

Chemistry – A European Journal published new progress about Adsorption. 3811-73-2 belongs to class pyridine-derivatives, and the molecular formula is C5H4NNaOS, Recommanded Product: 2-Mercaptopyridinen-oxide sodiumsalt.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ou, Wei; Zou, Ru; Han, Mengting; Yu, Lei; Su, Chenliang published the artcile< Tailorable carbazolyl cyanobenzene-based photocatalysts for visible light-induced reduction of aryl halides>, Computed Properties of 3796-23-4, the main research area is dehalogenation arylation photocatalyst carbazole.

Herein, a series of carbazolyl cyanobenzene (CCB)-based organic photocatalysts with a broad range of photoredox capabilities were designed and synthesized, allowing precise control of the photocatalytic reactivity for the controllable reduction of aryl halides via a metal-free process. The screened-out CCB (5CzBN), a metal-free, low-cost, scalable and sustainable photocatalyst with both strong oxidative and reductive ability, exhibits superior performance for both dehalogenation and C-C bond-forming arylation reactions.

Chinese Chemical Letters published new progress about Arylation. 3796-23-4 belongs to class pyridine-derivatives, and the molecular formula is C6H4F3N, Computed Properties of 3796-23-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Jian, Wenyuan; Jin, Zhengyu; Yang, Jing; Meng, Guozhe; Liu, Hongfang; Liu, Hongwei published the artcile< Anticorrosion and antibiofouling performance of in-situ prepared layered double hydroxide coating modified by sodium pyrithione on aluminum alloy 7075>, SDS of cas: 3811-73-2, the main research area is sodium pyrithione layered double hydroxide anticorrosion antibiofouling coating alloy.

The anticorrosion and antibiofouling of marine engineering equipments have strong demands, especially for antibiofouling. In this work, an in-situ growth layered double hydroxide (LDH) coating on aluminum alloys (AA) 7075 was prepared and then modified by sodium pyrithione (SPT) to increase the anticorrosion and antibiofouling performance. Results indicated that CoAl-LDHs and CoAl-LDHs-SPT coatings had been successfully prepared according to TEM, XRD, XPS, Raman spectra, and SEM anal. results. The (0 1 2) plane of LDHs with a interplanar spacing of 0.26 nm was recognized from TEM images. The content of SPT in CoAl-LDHs-SPT is 38.79 weight%. Electrochem. impedance spectroscopy (EIS) and polarization curves demonstrate that the corrosion resistance of AA 7075 was largely improved in the presence of CoAl-LDHs and CoAl-LDHs-SPT coatings while the anticorrosion performance of CoAl-LDHs-SPT coating was better. The corrosion resistance of Co-Al LDHs-SPT coating increased by about two orders of magnitude compared with the bare AA 7075. The surface anal. results show that only a few Pseudomonas aeruginosa and Spirulina cells attached to the CoAl-LDHs coating surface, and no biofouling cells were observed for the CoAl-LDHs-SPT coating. Co-Al LDHs-SPT coating possessed the best anticorrosion and antibiofouling properties due to the presence of SPT compared with the CoAl-LDHs coating.

Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) published new progress about Anion exchange. 3811-73-2 belongs to class pyridine-derivatives, and the molecular formula is C5H4NNaOS, SDS of cas: 3811-73-2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wang, Kaizhi; Jiang, Pengbo; Yang, Ming; Ma, Ping; Qin, Jiaheng; Huang, Xiaokang; Ma, Lei; Li, Rong published the artcile< Metal-free nitrogen -doped carbon nanosheets: a catalyst for the direct synthesis of imines under mild conditions>, Recommanded Product: Pyridin-4-ylmethanamine, the main research area is transfer hydrogenation nitrile nitrogen doped carbon nanocatalyst; imine preparation amine oxidation nitrile nitrogen doped carbon nanocatalyst.

Herein, a highly stable, porous, multifunctional and metal-free catalyst was developed, which exhibited significant catalytic performance in the oxidation of amines and transfer hydrogenation of nitriles under mild conditions; this could be attributed to the presence of numerous active sites and their outstanding BET surface area. The obtained results showed that most of the yields of imines exceeded 90%, and the cycling performance of the catalyst could be at least seven runs without any decay in the reaction activity, which could be comparable to those of metal catalysts. Subsequently, a kinetic study has demonstrated that the apparent activation energy for the direct synthesis of imines from amines is 67.39 kJ mol-1, which has been performed to testify that the catalytic performances are rational. Via catalyst characterizations and exptl. data, graphitic-N has been proven to be the active site of the catalyst. Hence, this study is beneficial to comprehend the mechanism of action of a metal-free N-doped carbon catalyst in the formation of imines.

Green Chemistry published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Recommanded Product: Pyridin-4-ylmethanamine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Yang, Zeyu; Fu, Hengwei; Ye, Wenjie; Xie, Youyu; Liu, Qinghai; Wang, Hualei; Wei, Dongzhi published the artcile< Efficient asymmetric synthesis of chiral alcohols using high 2-propanol tolerance alcohol dehydrogenase SmADH2 via an environmentally friendly TBCR system>, Category: pyridine-derivatives, the main research area is asym synthesis chiral alc propanol oxidation alc dehydrogenase; thermostatic bubble column reactor system alc dehydrogenase ketone reduction.

Alc. dehydrogenases (ADHs) together with the economical substrate-coupled cofactor regeneration system play a pivotal role in the asym. synthesis of chiral alcs.; however, severe challenges concerning the poor tolerance of enzymes to 2-propanol and the adverse effects of the byproduct, acetone, limit its applications, causing this strategy to lapse. Herein, a novel ADH gene smadh2 was identified from Stenotrophomonas maltophilia by traditional genome mining technol. The gene was cloned into Escherichia coli cells and then expressed to yield SmADH2. SmADH2 has a broad substrate spectrum and exhibits excellent tolerance and superb activity to 2-propanol even at 10.5 M (80%, volume/volume) concentration Moreover, a new thermostatic bubble column reactor (TBCR) system is successfully designed to alleviate the inhibition of the byproduct acetone by gas flow and continuously supplement 2-propanol. The organic waste can be simultaneously recovered for the purpose of green synthesis. In the sustainable system, structurally diverse chiral alcs. are synthesized at a high substrate loading (>150 g L-1) without adding external coenzymes. Among these, about 780 g L-1 (6 M) Et acetoacetate is completely converted into Et (R)-3-hydroxybutyrate in only 2.5 h with 99.9% ee and 7488 g L-1 d-1 space-time yield. Mol. dynamics simulation results shed light on the high catalytic activity toward the substrate. Therefore, the high 2-propanol tolerance SmADH2 with the TBCR system proves to be a potent biocatalytic strategy for the synthesis of chiral alcs. on an industrial scale.

Catalysis Science & Technology published new progress about Alcohols, chiral Role: BPN (Biosynthetic Preparation), BIOL (Biological Study), PREP (Preparation). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Category: pyridine-derivatives.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem