Tag: M.W=100-150

Aversa-Fleener, Cara R.; Chang, Daniel K.; Liberman-Martin, Allegra L. published the artcile< Carbodiphosphorane-Catalyzed Hydroboration of Ketones and Imines>, Quality Control of 350-03-8, the main research area is carbodiphosphorane catalyzed hydroboration ketone imine aldehyde; pinacol boronate ester preparation.

The authors report the use of a cyclic carbodiphosphorane catalyst for ketone and imine hydroboration reactions. Ketone hydroboration reactions are particularly rapid, typically reaching completion within 15 min using a 1 mol % catalyst loading at 25°. To the authors’ knowledge, this represents the 1st use of a carbodiphosphorane as an organocatalyst. The carbodiphosphorane exhibited superior catalytic activity in comparison to other neutral C nucleophiles tested, including an N-heterocyclic carbene, an N-heterocyclic olefin, and P ylides.

Organometallics published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Quality Control of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lemmens, Vincent; Vos, Christophe; Bugaev, Aram L.; Vercammen, Jannick; Van Velthoven, Niels; Gascon, Jorge; De Vos, Dirk E. published the artcile< Ru-Bipyridine Entrapped in the Supercages of EMC-1 Faujasite as Catalyst for the Trifluoromethylation of Arenes>, Reference of 3796-23-4, the main research area is hetero arene trifluoromethylation ruthenium bipyridine supercage faujasite catalyst photochem; Ru(bipy)32+; faujasite; heterogeneous catalysis; photocatalysis; trifluoromethylation.

Trifluoromethyl (CF3) groups are versatile structural motifs especially in the field of agrochems. and pharmaceuticals. However, current trifluoromethylation reactions are generally associated with stoichiometric amounts of transition metals/metal oxidants, homogeneous catalysts, high temperatures, and expensive trifluoromethylating agents. In this work, the homogeneous photocatalyst Ru(bipy)32+ is entrapped in the pores of a faujasite support (EMC-1) via a “”ship-in-a-bottle”” strategy. The formation of the coordination compound was confirmed by Fourier transform IR (FTIR), UV-Vis spectroscopy, and X-ray absorption spectroscopy (XAS). Due to its high stability toward acidified environments, this single-site heterogeneous catalyst is suitable for the trifluoromethylation of synthetically interesting (hetero)arenes under visible-light irradiation at room temperature Furthermore, the heterogeneous catalyst could efficiently be reused for at least three times with minimal catalyst leaching/deactivation.

ACS Applied Materials & Interfaces published new progress about Aromatic hydrocarbons Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3796-23-4 belongs to class pyridine-derivatives, and the molecular formula is C6H4F3N, Reference of 3796-23-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bazyar, Zahra; Tavakoliana, Mina; Hosseini-Sarvari, Mona published the artcile< Au-Pd@ZnO alloy nanoparticles: a promising heterogeneous photocatalyst toward decarboxylative trifluoromethylation under visible-light irradiation>, Electric Literature of 3796-23-4, the main research area is trifluoromethyl arene preparation; carboxylic acid decarboxylative trifluoromethylation palladium gold alloy nanoparticle photocatalyst.

Considering the high synergistic effect of Pd and Au supported on semiconductors, herein, Au-Pd@ZnO was synthesized and characterized with high potential toward the decarboxylative trifluoromethylation of aromatic carboxylic acids RCOOH (R = Ph, 1-naphthyl, benzthiophen-2-yl, etc.). Moreover, the combination of pyridine N-oxide and trifluoroacetic anhydride as a cost-effective and easy-to-handle source of CF3 could successfully generate the trifluoromethyl radical in the presence of the photocatalyst. To shed light on the synergistic effect of Pd and Au various control experiments were conducted, indicating the crucial role of both of them. This protocol was applicable to different aromatic and heteroaromatic compounds to deliver desired adducts in moderate to good yields and high functional group tolerance. Au-Pd@ZnO not only exhibited high catalytic performance but can also be recovered three times.

New Journal of Chemistry published new progress about Aromatic carboxylic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 3796-23-4 belongs to class pyridine-derivatives, and the molecular formula is C6H4F3N, Electric Literature of 3796-23-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hu, Chaopeng; Zhang, Jianying; Yang, Hao; Guo, Lulu; Cui, Chunming published the artcile< Synthesis of Cationic Silaamidinate Germylenes and Stannylenes and the Catalytic Application for Hydroboration of Pyridines>, HPLC of Formula: 350-03-8, the main research area is cationic silaamidinate germylene stannylene preparation catalyst hydroboration pyridine; crystal structure cationic silaamidinate germylene stannylene; mol structure cationic silaamidinate germylene stannylene; silaamidine deprotonation reaction germanium tin chloride.

The N-heterocyclic germylenes and stannylenes LSi(NAr)2EX (L = PhC(NtBu)2, Ar = 2,6-iPr2C6H3; E = Ge, Sn; X = Cl, CF3SO3, BPh4) supported by the bulky silaamidinate ligand [LSi(NAr)2]- were synthesized and fully characterized. The germylene triflate LSi(NAr)2GeOTf (3b) and dimeric borate [LSi(NAr)2Ge]2ClBPh4 (3a) enabled highly regio- and chemoselective catalytic hydroboration of pyridines and may represent the most active catalytic system for the transformation. DFT calculations disclosed that the cationic germylene [LSi(NAr)2Ge]+ with a low-lying LUMO energy initiated the catalytic process. In contrast, the analogous amidinate germylene triflates are almost inactive, indicating the silaamidinate ligand is essential for the stabilization of cationic species.

Inorganic Chemistry published new progress about Amidination. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, HPLC of Formula: 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ozturkkan Ozbek, Fureya Elif; Ugurlu, Guventurk; Kalay, Erbay; Necefoglu, Hacali; Hokelek, Tuncer published the artcile< Theoretical and experimental assessment of structural, spectroscopic, electronic and nonlinear optical properties of two aroylhydrazone derivative>, Related Products of 93-60-7, the main research area is structural spectroscopic electronic nonlinear optical property aroylhydrazone derivative.

Two aroylhydrazone, N’-(pyridine-4-ylmethylene)nicotic acid hydrazide (1) and N’-(pyridine-3-ylmethylene)nicotic acid hydrazide (2), were synthesized and their structures were determined by single-crystal X-ray diffraction anal. The X-ray anal. indicated that the compound 1 was crystallized in triclinic crystal system with P -1 space group a = 8.7899 (2) Å, b = 10.8983 (3) Å, c = 11.7726 (3) Å, α= 89.952 (3)°, β = 88.684 (3)°, γ= 75.293 (2)°, V = 1090.50 (5) Å3 and Z = 4 and compound 2 was crystallized in monoclinic crystal system with P21/c space group, a = 11.9239 (3) Å, b = 8.6495 (2) Å, c = 11.1021 (3) Å, α= 90 (3)°, β = 111.664 (3) (3)°, γ= 90°, V = 1064.14 (5) Å3 and Z = 4. Intermol. interactions of the compounds were determined by Hirhfeld Surface Anal. The H ··· H interactions with 37.9% (for compound 1) and 37.5% (for compound 2) contributions are the most important interactions to the overall crystal packings. FT-IR, Raman, 1H and 13C NMR and UV-Vis spectroscopy methods were used for spectroscopic characterization of the compounds The spectroscopic properties of the compounds were calculated theor. by using D. Functional Theory (DFT) with B3LYP and ab initio Hartree-Fock (HF) methods at different basis sets. A correlation was found between the theor. and exptl. values for the spectroscopic results. Moreover, the HOMO (HOMO), the LUMO (LUMO), elec. dipole moment (μ), polarizability (α) and hyperpolarizability (β) of the compounds were computed both DFT/B3LYP/6-311++G(d,p) and ab initio HF/6-311++G(d,p) methods. The calculated first hyperpolarizability value at the DFT/B3LYP/6-31++G (d,p) level of compound 1 with dimer structure is 18.14 times larger than urea, the standard nonlinear optical material. So, this value implies that compound 1 considered have potential candidates for designing high quality nonlinear optical materials. The energy gap (ΔEgap) and Mol. Electrostatic Potential (MEP) of the compounds were investigated. The structural and vibration frequency values calculated theor. were compared with the exptl. values.

Journal of Molecular Structure published new progress about Band gap. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Related Products of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Meng, Genyi; Guo, Taijie; Ma, Tiancheng; Zhang, Jiong; Shen, Yucheng; Sharpless, Karl Barry; Dong, Jiajia published the artcile< Modular click chemistry libraries for functional screens using a diazotizing reagent>, Computed Properties of 56622-54-9, the main research area is alkyl aryl azide triazole chemoselective preparation; fluorosulfonyl azide generation chemoselective diazotization primary amine; combinatorial generation library alkyl aryl azide cycloaddition alkyne; functional screen click chem azide generated in situ.

Alkyl and aryl azides were prepared from the corresponding primary alkyl and aryl amines by reaction with fluorosulfonyl azide generated in situ from a fluorosulfonylimidazolium triflate and sodium azide, expanding access to azides and both to the 1,2,3-triazoles derived from them and to functional screens employing them. The method allowed the preparation of a library of >1000 azides from the corresponding amines; the azide library underwent copper-catalyzed azide-alkyne cycloaddition reactions to yield a library of >1000 1,2,3-triazoles.

Nature (London, United Kingdom) published new progress about Alkyl azides Role: CMB (Combinatorial Study), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 56622-54-9 belongs to class pyridine-derivatives, and the molecular formula is C7H10N2, Computed Properties of 56622-54-9.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Youssef, Heba; Sedykh, Alexander E.; Becker, Jonathan; Schafer, Thomas; Taydakov, Ilya V.; Li, Huanrong R.; Mueller-Buschbaum, Klaus published the artcile< Variable Luminescence and Chromaticity of Homoleptic Frameworks of the Lanthanides together with Pyridylpyrazolates>, Electric Literature of 350-03-8, the main research area is lanthanide pyridylpyrazolate coordination polymer homoleptic framework chromaticity luminescence; rare earth pyridylpyrazolate coordination polymer homoleptic framework chromaticity luminescence; N ligands; coordination polymers; homoleptic; lanthanides; luminescence.

Homoleptic, 3D coordination polymers of the formula 33∞[Ln(3-PyPz)3] and 3∞[Ln(4-PyPz)3], (3-PyPz)- = 3-(3-pyridyl)pyrazolate anion, (4-PyPz)- = 3-(4-pyridyl)pyrazolate anion, both C8H6N3-, Ln = Sm, Eu, Gd, Tb, Dy, were obtained as highly luminescent frameworks by reaction of the lanthanide metals (Ln) with the aromatic heterocyclic amine ligands 3-PyPzH and 4-PyPzH. The compounds form 2 isotypic series of 3D coordination polymers and exhibit fair thermal stability up to 360°. The luminescence properties of all 10 compounds were determined in the solid state, with an antenna effect through ligand-metal energy transfer leading to high efficiency of the luminescence displayed by good quantum yields of up to 74%. The emission is mainly based on ion-specific lanthanide-dependent intra 4f-4f transitions for Tb3+: green, Dy3+: yellow, Sm3+: orange-red, Eu3+: red. For the Gd3+-containing compounds, the yellow emission of ligand triplet-based phosphorescence is observed at room temperature and 77 K. Codoping of the Gd-containing frameworks with Eu3+ and Tb3+ allow further shifting of the chromaticity towards white light emission.

Chemistry – A European Journal published new progress about Color. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Electric Literature of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lenstra, Danny C.; Lenting, Peter E.; Mecinovic, Jasmin published the artcile< Sustainable organophosphorus-catalysed Staudinger reduction>, Name: 2-Fluoro-3-(hydroxymethyl)pyridine, the main research area is amine green preparation; azide Staudinger reduction.

A highly efficient and sustainable catalytic Staudinger reduction for the conversion of organic azides to amines in excellent yields was developed. The reaction displayed excellent functional group tolerance to functionalities that were otherwise prone to reduction, such as sulfones, esters, amides, ketones, nitriles, alkenes and benzyl ethers. The green nature of the reaction was exemplified by the use of PMHS, CPME and a lack of column chromatog.

Green Chemistry published new progress about Alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 131747-55-2 belongs to class pyridine-derivatives, and the molecular formula is C6H6FNO, Name: 2-Fluoro-3-(hydroxymethyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Edelsbacher, Philipp; Redhammer, Guenther; Monkowius, Uwe published the artcile< Copper(II) complexes bearing cyclobutanecarboxylate and pyridine ligands: a new series of dinuclear paddle-wheel complexes>, Related Products of 93-60-7, the main research area is copper cyclobutanecarboxylate pyridine complex preparation; crystal structure copper cyclobutanecarboxylate pyridine.

Four members of a new series of paddle-wheel copper(II) complexes bearing cyclobutanecarboxylate as bridging ligand with pyridine derived ligands in axial positions are reported. They have been characterized by FTIR-ATR, UV-Vis spectroscopy, mass spectrometry, and single crystal X-ray diffraction. The synthesis is straight-forward by combining the carboxylic acid, copper(II) acetate, and a slight excess of a pyridine ligand. The mol. structures of three complexes reveal a coordination mode expected for such type of dinuclear copper(II) carboxylates.

Monatshefte fuer Chemie published new progress about Crystal structure. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Related Products of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Matsa, Ramkishore; Makam, Parameshwar; Sethi, Guneswar; Thottasseri, Ahammed Ameen; Kizhakkandiyil, Aswani Raj; Ramadas, Krishna; Mariappan, Vignesh; Pillai, Agieshkumar Balakrishna; Kannan, Tharanikkarasu published the artcile< Pyridine appended 2-hydrazinylthiazole derivatives: design, synthesis, in vitro and in silico antimycobacterial studies>, Quality Control of 350-03-8, the main research area is hydrazinyl thiazole pyridinyl preparation docking antitubercular cytotoxicity lipophilicity.

An array of pyridine appended 2-hydrazinylthiazole derivatives I (R1 = Me, Ph, 1-naphthyl, 3-pyridyl, etc.; R2 = H, Me) has been synthesized to discover novel chemotherapeutic agents for Mycobacterium tuberculosis (Mtb). The drug-likeness of pyridine appended 2-hydrazinylthiazole derivatives I was validated using the Lipinski and Veber rules. The designed thiazole mols. have been synthesized through Hantzsch thiazole methodologies. The in vitro antimycobacterial studies have been conducted using Luciferase reporter phage (LRP) assay. Out of thirty derivatives, the compounds I (R1 = Ph, R2 = H, Me; R1 = 2-FC6H4, R2 = H; R1 = 4-FC6H4, R2 = Me) exhibited good antimycobacterial activity against Mtb, an H37Rv strain, with the min. inhibitory concentration in the range of 6.40-7.14μM. In addition, in vitro cytotoxicity of active mols. has been observed against Human Embryonic Kidney Cell lines (HEK293t) using MTT assay. The compounds I (R1 = Ph, 4-FC6H4; R2 = Me) are nontoxic and their cell viability is 87% and 96.71% resp. The in silico analyses of the pyridine appended 2-hydrazinylthiazole derivatives have been used to find the mode of binding of the active compounds with KasA protein of Mtb. The active compounds showed a strong binding score (-5.27 to -6.23 kcal mol-1).

RSC Advances published new progress about Alkyl aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Quality Control of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem