Tag: M.W=100-150

Gonzalez, Alexandre; Benfodda, Zohra; Benimelis, David; Fontaine, Jean-Xavier; Molinie, Roland; Meffre, Patrick published the artcile< Extraction and Identification of Volatile Organic Compounds in Scentless Flowers of 14 Tillandsia Species Using HS-SPME/GC-MS>, Electric Literature of 93-60-7, the main research area is Tillandsia volatile organic compound flower mass spectrometry; PCA analysis; Tillandsia; faint-scented flowers; gas chromatography-mass spectrometry (GC-MS); headspace solid phase microextraction (HS-SPME); heatmap; scentless flowers; volatile organic compounds (VOCs).

VOCs emitted by flowers play an important role in plant ecol. In the past few years, the Tillandsia genus has been scarcely studied according to the VOCs emitted by flowers. Hence, we decided to enlarge the VOCs composition study already undergone in our laboratory on fragrant 3 Tillandsia species to 12 unscented and 2 faint-scented Tillandsia species and hybrids. The headspace solid phase microextraction (HS-SPME) coupled with gas chromatog. combined with the mass spectrometry (GC-MS) method was used to explore the chem. diversity of the VOCs. This study allowed the identification of 65 VOCs among the 14 species and between 6 to 25 compounds were identified in each of the species. The aromatic profile of 10 of the species and hybrids are similar to each other′s and show 8 predominant compounds: benzaldehyde, benzacetaldehyde, hexanol, hexanal, heptanal, octanal, nonanal, and furan-2-pentyl. Some specific compounds are present only in some unique species such as trans-calamenene, α-muurolene, and α-guaiene trans-β-bergamotene. The two faint-scented species studied present an original aromatic profile with a high number of monoterpenes or phenylpropanoids/benzenoids. Our studies allow a better understanding of the ecol. role and function of these VOCs in the interactions between these plants with their environment.

Metabolites published new progress about Aliphatic alcohols Role: ANT (Analyte), BSU (Biological Study, Unclassified), PAC (Pharmacological Activity), THU (Therapeutic Use), ANST (Analytical Study), BIOL (Biological Study), USES (Uses). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Electric Literature of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chhem-Kieth, Sorivan; Lametsch, Rene; Hansen, Erik Torngaard; Ruiz-Carrascal, Jorge published the artcile< Storage and thermal stability of novel heme-based pigments prepared from porcine hemoglobin>, Product Details of C7H7NO2, the main research area is porcine Hb heme pigment storage thermal stability.

The stability of novel meat pigments derived from heme-enriched extract obtained from porcine Hb was assessed. Four different ligands (sodium nitrite, 4-methylimidazole, Me nicotinate, and pyrazine) were used to produce spray-dried, microencapsulated heme-ligand complexes. The storage and thermal stabilities of the produced pigments were assessed, over a 6-mo storage period and across a temperature range of 25-75°C. Color measurements and evaluation were made on the dissolved pigments by UV-visible absorbance spectroscopy and CIELAB color space. All heme-ligand complexes exhibited a stable red color across the storage period, except for the heme-Me nicotinate adduct, which color faded to brown after 30 days of storage. For thermal stability, only the heme-4-methylimidazole complex did not retain its red color beyond 55°C. The redness of the heme-pyrazine complex showed improvement upon heating, which is proposed to be due to the degradation of polymeric heme-pyrazine structure formed during the ligation process. Due to the global effort to reduce nitrite addition in food product, there is an important interest to replace it in processed meat products, wholly or in part. Addnl., the perspective of optimizing the usage of an under-utilized blood fraction is attractive for the meat industry. The development of a heme pigment derived from porcine blood thus presents a good com. potential. Two important aspects of such product would be its stability upon storage, or during heat treatment to levels similar to what is used in processed, cooked meat products. This study presents the behavior for those two aspects of different heme-ligand complexes, and compares the results obtained with a heme pigment produced from the traditionally used nitrite.

Journal of Food Process Engineering published new progress about Blood. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Product Details of C7H7NO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kalindjian, S. Barret; Kadnur, Sanjay V.; Hewson, Christopher A.; Venkateshappa, Chandregowda; Juluri, Suresh; Kristam, Rajendra; Kulkarni, Bheemashankar; Mohammed, Zainuddin; Saxena, Rohit; Viswanadhan, Vellarkad N.; Aiyar, Jayashree; McVey, Donna published the artcile< A New Series of Orally Bioavailable Chemokine Receptor 9 (CCR9) Antagonists; Possible Agents for the Treatment of Inflammatory Bowel Disease>, Quality Control of 56622-54-9, the main research area is dioxoisoindoline derivative preparation CCR9 antagonist inflammatory bowel disease pharmacokinetics.

Chemokine receptor 9 (CCR9), a cell surface chemokine receptor which belongs to the G protein-coupled receptor, 7-trans-membrane superfamily, is expressed on lymphocytes in the circulation and is the key chemokine receptor that enables these cells to target the intestine. It has been proposed that CCR9 antagonism represents a means to prevent the aberrant immune response of inflammatory bowel disease in a localized and disease specific manner and one which is accessible to small mol. approaches. One possible reason why clin. studies with vercirnon, a prototype CCR9 antagonist, were not successful may be due to a relatively poor pharmacokinetic (PK) profile for the mol. We wish to describe work aimed at producing new, orally active CCR9 antagonists based on the 1,3-dioxoisoindoline skeleton. This study led to a number of compounds that were potent in the nanomolar range and which, on optimization, resulted in several possible preclin. development candidates with excellent PK properties.

Journal of Medicinal Chemistry published new progress about Anti-inflammatory agents. 56622-54-9 belongs to class pyridine-derivatives, and the molecular formula is C7H10N2, Quality Control of 56622-54-9.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Dong, Zhen; Liu, Junzi; Wen, Di; Zhai, Maolin; Zhao, Long published the artcile< Aminomethylpyridine isomers functionalized cellulose microspheres for TcO-4/ReO-4 uptake: Structure-properties relationship and their application in different aquatic systems>, Safety of Pyridin-4-ylmethanamine, the main research area is cellulose aminomethylpyridine isomer technetium rhenium oxide adsorption; (99)Tc; Adsorption mechanism; ReO(4)(-); Removal; Structure-properties relationship.

Technetium-99 (99Tc) is a long-lived radioactive nuclide that poses great threat to environment, hence selective removal of 99Tc from aquatic system is always an issue. Aminomethylpyridine (AMP) equipped with pyridine and amino, is a promising receptor for TcO4- and its surrogate ReO4-, thus it is of interest to explore and understand the structure-properties relationship of ReO4- adsorption related to n-AMP structure that differ in amino Me position. In this work, three n-AMP functionalized cellulose microspheres (n-AMPR, n = 2, 3, 4) were synthesized and employed for TcO4-/ReO4- uptake. The effect of aminomethyl position on adsorption properties of n-AMPR for ReO4- were investigated and compared. Adsorption kinetics and adsorption isotherm showed that adsorption speed and adsorption capacity were in order of 3-AMPR > 2-AMPR > 4-AMPR. DFT calculation verified that the adsorption of ReO4- by n-AMPR was attributed to electrostatic interaction and hydrogen bonding interaction, the order of adsorption abilities of n-AMPR was due to that steric effect and hydrogen bond collaborated in stabilizing n-AMPR-ReO4- complexes. The column experiments demonstrated that 3-AMPR can be selectively remove ReO4- from simulated groundwater. More importantly, 99Tc column experiments showed that 3-AMPR had a better ability for actual radioactive TcO4-.

Journal of Hazardous Materials published new progress about Adsorption. 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Safety of Pyridin-4-ylmethanamine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kowalkowska-Zedler, D.; Dolega, A.; Nedelko, N.; Lyszczek, R.; Aleshkevych, P.; Demchenko, I.; Luczak, J.; Slawska-Waniewska, A.; Pladzyk, A. published the artcile< Structural, magnetic and spectral properties of tetrahedral cobalt(II) silanethiolates: a variety of structures and manifestation of field-induced slow magnetic relaxation>, Name: Pyridin-4-ylmethanamine, the main research area is cobalt silanethiolate aminopyridine aminomethylpyridine complex preparation magnetic property; thermal stability cobalt silanethiolate aminopyridine aminomethylpyridine; crystal structure cobalt silanethiolate aminopyridine aminomethylpyridine.

Blue crystals of five heteroleptic cobalt(II) silanethiolates 1-5 have been obtained by the reaction of [Co{SSi(tBuO)3}2(NH3)]2 with aminopyridines and aminomethylpyridines at an appropriate molar ratio and their structural, spectral, thermal and magnetic properties have been established and described. All complexes 1-5 contain Co(II) ions in a tetrahedral CoN2S2 environment formed by (tBuO)3SiS- residues and pyridines and present variable structures. Complexes 1-3 are mononuclear [Co{SSi(tBuO)3}2(L1)2] (L1 = 2-aminopyridine 2AP, 3-aminopyridine 3AP, and 4-aminopyridine 4AP). The application of 3AMP and 4AMP (3-aminomethylpyridine and 4-aminomethylpyridine) allows either dinuclear complex 4 [Co{SSi(tBuO)3}2(μ-3AMP)]2 or 1D coordination polymer 5 with the formula of [Co{SSi(tBuO)3}2(μ-4AMP)]n to be obtained. The mol. structures of 1-5 were determined by single-crystal X-ray and powder diffraction, UV-vis and FTIR spectrocopy for solid samples and their thermal properties were characterized by TG-DSC and TG-FTIR methods. The dc and ac magnetic and EPR studies of polycrystalline samples have been performed. For all complexes, the obtained data show a behavior typical of paramagnetic high-spin Co(II) ions in a tetrahedral geometry, with a considerable contribution of the ZFS effect in a low temperature range. All complexes were also probed for SIM behavior. The modeling of the magnetic and EPR data was done for samples 1, 3, 4 and 5 to estimate ZFS parameters. The obtained results imply a neg. value of the axial parameter D in complex 4 and pos. D values for the rest of the compounds A comparative magneto-structural anal. of complexes 4 and 5 points to the high sensitivity of the single-ion magnetic anisotropy of tetrahedral Co(II) complexes to subtle changes in the first and second coordination spheres of Co(II) ions.

Dalton Transactions published new progress about Aminopyridines Role: PEP (Physical, Engineering or Chemical Process), PRP (Properties), SPN (Synthetic Preparation), PROC (Process), PREP (Preparation) (cobalt complexes). 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Name: Pyridin-4-ylmethanamine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Knight, Brian J.; Tolchin, Zachary A.; Smith, Joel M. published the artcile< A predictive model for additions to N-alkyl pyridiniums>, Recommanded Product: 3-(Methoxycarbonyl)pyridine, the main research area is pyridine Grignard methyl triflate regioselective dearomative addition; dihydropyridine preparation.

Disclosed in this communication is a thorough study on the dearomative addition of organomagnesium nucleophiles to N-alkyl pyridinium electrophiles. The regiochem. outcomes have observable and predictable trends associated with the substituent patterns on the pyridinium electrophile. Often, the substituent effects can be either additive, giving high selectivities, or ablative, giving competing outcomes. Addnl., the nature of the organometallic nucleophilic component was also investigated for its role in the regioselective outcome. The effects of either reactive component are important to both the overall reactivity and site of nucleophilic addition The utility of these observed trends is demonstrated in a concise, dearomative synthesis of a tricyclic compound shown to have insecticidal activity.

Chemical Communications (Cambridge, United Kingdom) published new progress about Dearomatization. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Recommanded Product: 3-(Methoxycarbonyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reusch, Engelbert; Holzmeier, Fabian; Gerlach, Marius; Fischer, Ingo; Hemberger, Patrick published the artcile< Decomposition of Picolyl Radicals at High Temperature: A Mass Selective Threshold Photoelectron Spectroscopy Study>, HPLC of Formula: 3731-53-1, the main research area is picolyl radical decomposition mechanism potential energy surface; ionization energy; photoelectron spectroscopy; pyrolysis; radicals; synchrotron radiation.

The reaction products of the picolyl radicals at high temperature were characterized by mass-selective threshold photoelectron spectroscopy in the gas phase. Aminomethylpyridines were pyrolyzed to initially produce picolyl radicals (m/z=92). At higher temperatures further thermal reaction products are generated in the pyrolysis reactor. All compounds were identified by mass-selected threshold photoelectron spectroscopy and several hitherto unexplored reactive mols. were characterized. The mechanism for several dissociation pathways was outlined in computations. The spectrum of m/z=91, resulting from hydrogen loss of picolyl, shows four isomers, two ethynyl pyrroles with adiabatic ionization energies (IEad) of 7.99 eV (2-ethynyl-1H-pyrrole) and 8.12 eV (3-ethynyl-1H-pyrrole), and two cyclopentadiene carbonitriles with IE’s of 9.14 eV (cyclopenta-1,3-diene-1-carbonitrile) and 9.25 eV (cyclopenta-1,4-diene-1-carbonitrile). A second consecutive hydrogen loss forms the cyanocyclopentadienyl radical with IE’s of 9.07 eV (T0) and 9.21 eV (S1). This compound dissociates further to acetylene and the cyanopropynyl radical (IE=9.35 eV). Furthermore, the cyclopentadienyl radical, penta-1,3-diyne, cyclopentadiene and propargyl were identified in the spectra. Computations indicate that dissociation of picolyl proceeds initially via a resonance-stabilized seven-membered ring.

Chemistry – A European Journal published new progress about Adiabatic ionization potential. 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, HPLC of Formula: 3731-53-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bird, Clive W. published the artcile< Heteroaromaticity. 7. Some quantitative aspects of the tauomerism of hydroxy and mercapto azines>, Synthetic Route of 73018-09-4, the main research area is aromaticity hydroxy azine tautomer crystallog; resonance energy change tautomerization; mercapto azine tautomerism.

Aromaticity indexes have been calculated from crystallog. data for a range of oxo tautomers of hydroxy azines. The differences between these indexes and those for the hydroxy azines lead to values for changes in resonance energies accompanying tautomerization. These values are closely parallel to those previously measured for the same process in aqueous solution

Tetrahedron published new progress about Aromatic nitrogen heterocycles Role: PRP (Properties). 73018-09-4 belongs to class pyridine-derivatives, and the molecular formula is C5H4ClNO, Synthetic Route of 73018-09-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chen, Dong-Mei; Wu, Xiao-Fan; Liu, Yong-Jie; Huang, Chao; Zhu, Bi-Xue published the artcile< Synthesis, crystal structures and vapor adsorption properties of Hg(II) and Cd(II) coordination polymers derived from two hydrazone Schiff base ligands>, Electric Literature of 350-03-8, the main research area is cadmium mercury Schiff aminobenzoylhydrazide acetylpyridine complex preparation gas adsorption; crystal structure cadmium mercury Schiff aminobenzoylhydrazide acetylpyridine complex.

Four coordination polymers, [HgL1Br2]n (1), {[Cd(L1)2Cl2]·2CH3OH}n (2), [HgL2Cl2]n (3) and [Cd(L2)2Cl2]n (4), were synthesized and characterized from two hydrazone Schiff base ligands (L1 and L2) with mercury(II) or cadmium(II) halide, resp. In complexes 1 and 3, each mercury(II) center is five-coordinated with distorted square pyramidal geometry in 1-dimensional coordination polymers. In complexes 2 and 4, each cadmium(II) center is six-coordinated with slightly distorted octahedral geometry in 1-dimensional looped-chain structures. The ligands show different coordination sites in the formation of coordination polymers. In complexes 2, 3 and 4, the ligands coordinate to the metal centers by pyridine nitrogen atoms and amino nitrogen atoms, whereas in complex 1 it coordinates by pyridine nitrogen atoms and carbonyl oxygen atoms instead of amino nitrogen atoms.

Inorganica Chimica Acta published new progress about Crystal structure. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Electric Literature of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Slepukhin, P. A.; Boltacheva, N. S.; Filyakova, V. I.; Charushin, V. N. published the artcile< Synthesis and structure of lithium 3-trifluoromethyl-1,3-diketonates containing pyridyl substituents>, Electric Literature of 350-03-8, the main research area is lithium fluoromethyldiketonate preparation crystal structure.

Lithium 3-trifluoromethyl-1,3-diketonates containing pyridyl substituents were synthesized. The specific features of the crystal structures of Li (Z)-1,1,1-trifluoro-4-oxo-4-(pyridin-3-yl)- and (Z)-1,1,1-trifluoro-4-oxo-4-(pyridin-4-yl)but-2-en-2-olates were revealed by x-ray diffraction. These compounds have a polymeric structure with Li cations in different coordination modes. The 1,3-diketonate group is involved in chelation and formation of O bridges, thereby linking two types of Li atoms.

Russian Chemical Bulletin published new progress about Crystal structure. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Electric Literature of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem