Tag: M.W=150-200

Duan, Lele published the artcileInsights into Ru-Based Molecular Water Oxidation Catalysts: Electronic and Noncovalent-Interaction Effects on Their Catalytic Activities, Safety of Pyridine-3-sulfonic acid, the publication is Inorganic Chemistry (2013), 52(14), 7844-7852, database is CAplus and MEDLINE.

A series of Ru-bda water oxidation catalysts [Ru(bda)L₂] (H₂bda = 2,2′-bipyridine-6,6′-dicarboxylic acid; L = [HNEt₃][3-SO₃-pyridine], 1; 4-(EtOOC)-pyridine, 2; 4-bromopyridine, 3; pyridine, 4; 4-methoxypyridine, 5; 4-(Me₂N)-pyridine, 6; 4-[Ph(CH₂)₃]-pyridine, 7) were synthesized with electron-donating/-withdrawing groups and hydrophilic/hydrophobic groups in the axial ligands. These complexes were characterized by ¹H NMR spectroscopy, high-resolution mass spectrometry, elemental anal., and electrochem. In addition, complexes 1 and 6 were further identified by single crystal X-ray crystallog., revealing a highly distorted octahedral configuration of the Ru coordination sphere. All of these complexes are highly active toward Ce^IV-driven (Ce^IV = Ce(NH₄)₂(NO₃)₆) water oxidation with oxygen evolution rates up to 119 mols of O₂ per mol of catalyst per s. Their structure-activity relationship was investigated. Electron-withdrawing and noncovalent interactions (attraction) exhibit pos. effect on the catalytic activity of Ru-bda catalysts.

Inorganic Chemistry published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Safety of Pyridine-3-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Zhu, Tong-Hao published the artcileCo(acac)₂/O₂-Mediated Oxidative Isocyanide Insertion with 2-Aryl Anilines: Efficient Synthesis of 6-Amino Phenanthridine Derivatives, Recommanded Product: 2-Bromopyridin-3-amine, the publication is Organic Letters (2014), 16(4), 1260-1263, database is CAplus and MEDLINE.

A novel and efficient protocol for the creation of 6-amino phenanthridine derivatives, e.g., I, by Co(acac)₂-catalyzed isocyanide insertion with 2-aryl anilines under an O₂ atmosphere via homolytic aromatic substitution (HAS) type C-H functionalization has been developed. This reaction not only proceeds smoothly utilizing O₂ as the oxidant but also provides a new approach to construct phenanthridine derivatives utilizing readily available 2-aryl anilines with isocyanides instead of 2-isocyanobiaryls with different radical precursors.

Organic Letters published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C7H12ClNO, Recommanded Product: 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Nan, Xiao-Lei published the artcileSite-selective D₂O-mediated deuteration of diaryl alcohols via quantum dots photocatalysis, COA of Formula: C12H9NO, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(55), 6768-6771, database is CAplus and MEDLINE.

Owing to the high synthetic value of deuteration in the pharmaceutical industry, the conversion of a range of aromatic ketones to deuterium-labeled products such as RR¹CD(OH) [R = Ph, 4-ClC₆H₄, 4-BrC₆H₄, 4-CNC₆H₄, 4-PhC₆H₄; R¹ = Ph, 2-thienyl, 2-naphthyl, etc.] in good to excellent yields was described. Efficient and site-selective deuteration of benzyl alcs. by D₂O with visible light irradiation of quantum dots (QDs), together with gram-scale synthesis and photocatalyst recycling experiments indicated the potential of the developed method in practical organic synthesis.

Chemical Communications (Cambridge, United Kingdom) published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, COA of Formula: C12H9NO.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Leng, Faqiang published the artcileFacile synthesis of trifluoroethyl compounds by the Suzuki cross-coupling reactions of CF₃CH₂OTs with arylboronic acids, Synthetic Route of 774170-15-9, the publication is Chemical Communications (Cambridge, United Kingdom) (2013), 49(91), 10697-10699, database is CAplus and MEDLINE.

This research provides a novel approach for introducing a CF₃CH₂ group onto aromatic rings using Pd(OAc)₂/palladacycle as a catalyst for the Suzuki cross-coupling reaction of CF₃CH₂OTs (OTs = 4-methylbenzene sulfonate) with arylboronic acids.

Chemical Communications (Cambridge, United Kingdom) published new progress about 774170-15-9. 774170-15-9 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester,Amine,Boronic Acids, name is (6-(Methylamino)pyridin-3-yl)boronic acid, and the molecular formula is C6H9BN2O2, Synthetic Route of 774170-15-9.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Ban, Yan published the artcileThioamide directed iridium(I)-catalyzed C-H arylation of ferrocenes with aryl boronic acids, Computed Properties of 612845-44-0, the publication is Organic & Biomolecular Chemistry (2022), 20(29), 5759-5763, database is CAplus and MEDLINE.

The first Ir(I)-catalyzed thioamide-assisted C-H arylation of ferrocenes with aryl boronic acids under base-free mild reaction conditions in the presence of Ag₂CO₃ as an oxidant with eco-friendly 2-MeTHF as a solvent was developed. This reaction has a wide range of substrates (37 examples) and functional group tolerance (18-94% yields), and provides promising access to aryl thioamide-ferrocene compounds with good yields and regioselectivity.

Organic & Biomolecular Chemistry published new progress about 612845-44-0. 612845-44-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester,Ether,Boronic Acids,Boronic acid and ester, name is (6-Ethoxypyridin-3-yl)boronic acid, and the molecular formula is C7H10BNO3, Computed Properties of 612845-44-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Wang, Qiang published the artcileIntroducing electrostatic interaction into Ru(bda) complexes for promoting water-oxidation catalysis, Related Products of pyridine-derivatives, the publication is Journal of Molecular Structure (2021), 130745, database is CAplus.

Ru(bda) (H₂bda = 2,2â€?bipyridine-6,6â€?dicarboxylic acid) complex is a kind of well-known water oxidation catalyst, which goes through the bimol. I2M mechanism with an inter-catalyst O-O coupling step. Recently, we developed two facile strategies to accelerate O-O coupling via introducing the electrostatic interaction into Ru(bda)-catalyzed systems. In this work, a series of Ru(bda) complexes with different charged groups on different positions were synthesized to demonstrate the general applicability of these design strategies. It found these catalytic systems with attractive electrostatic interaction display much better activity, and the position of the charged substituents also has a significant influence on the catalytic activity.

Journal of Molecular Structure published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C8H6ClN, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Panicker, C. Yohannan published the artcileFT-IR, FT-Raman and SERS spectra of pyridine-3-sulfonic acid, Application In Synthesis of 636-73-7, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2006), 64A(3), 744-747, database is CAplus and MEDLINE.

FTIR and FT-Raman spectra of pyridine-3-sulfonic acid are recorded and analyzed. Surface enhanced Raman scattering (SERS) spectrum is recorded in a Ag colloid. The bands due to υCH, υSO are enhanced in the SERS spectrum. A likely perpendicular orientation’ of the mol. on the Ag surface is suggested.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Application In Synthesis of 636-73-7.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Kandasamy, M. published the artcileMolecular structure and vibrational spectra of 3-and 4-amino-2-bromopyridine by density functional methods, Safety of 2-Bromopyridin-3-amine, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2012), 206-216, database is CAplus and MEDLINE.

Exptl. and theor. study on the mol. structure and the vibrational spectra of 3-amino-2-bromopyridine (Compound I) and 4-amino-2-bromopyridine (Compound II) are presented. The vibrational frequencies of these compounds were obtained theor. by DFT/B3LYP employing the 6-311G(2df,2p) basis set for optimized geometries and were compared with FTIR solid phase spectra (FTIR) at 400-4000 cm^-1, FT-Raman spectra at 100-4000 cm^-1 and with solution phase spectra at 400-4000 cm^-1. Complete vibrational assignment, anal. and correlation of the fundamental modes for these compounds were carried based on the potential energy distribution (PED). The vibrational harmonic frequencies were scaled using scale factors, yielding a good agreement between the exptl. recorded and the theor. calculated values. Finally the calculated HOMO and LUMO energies are localized on the entire ring and substituents.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Safety of 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Elie, Jonathan published the artcileDesign of selective COX-2 inhibitors in the (aza)indazole series. Chemistry, in vitro studies, radiochemistry and evaluations in rats of a [¹⁸F] PET tracer, Quality Control of 612845-44-0, the publication is Journal of Enzyme Inhibition and Medicinal Chemistry (2019), 34(1), 1-7, database is CAplus and MEDLINE.

A series of novel derivatives exhibiting high affinity and selectivity towards the COX-2 enzyme in the (aza) indazole series was developed. A short synthetic route involving a bromination/arylation sequence under microwave irradiation and direct C-H activation were established in the indazole and azaindazole series resp. In vitro assays were conducted and structural modifications were carried out on these scaffolds to furnish compound which exhibited effective COX-2 inhibitory activity, with IC₅₀ values of 0.409 μM and an excellent selectivity vs. COX-1. Radiolabeling of this most potent derivative [¹⁸F] was achieved after boron ester release and the tracer was evaluated in vivo in a rat model of neuroinflammation. All chem., radiochem. and biol. exptl. data are discussed.

Journal of Enzyme Inhibition and Medicinal Chemistry published new progress about 612845-44-0. 612845-44-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester,Ether,Boronic Acids,Boronic acid and ester, name is (6-Ethoxypyridin-3-yl)boronic acid, and the molecular formula is C7H10BNO3, Quality Control of 612845-44-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Bumagin, N. A. published the artcileAn effective activation of palladium phosphine complexes in aqueous phase reactions of heteroaromatic boronic acids with aryl halides, Formula: C5H5BrN2, the publication is Chemistry of Heterocyclic Compounds (New York, NY, United States) (2014), 50(1), 19-25, database is CAplus.

A simple and effective method was developed for the activation of palladium-phosphine complexes in the Suzuki reaction (TON up to 9800, TOF up to 58800 h^-1) by selecting an aqueous reaction medium instead of organic solvents. This method was elaborated for a high yield synthesis of heteroaromatic biaryls with furyl and thienyl groups.

Chemistry of Heterocyclic Compounds (New York, NY, United States) published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Formula: C5H5BrN2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem