Tag: M.W=150-200

Han, Fei published the artcileEffect of functional group position change of pyridinesulfonic acid as interface-modified layer on perovskite solar cell, Formula: C5H5NO3S, the publication is Applied Surface Science (2018), 517-525, database is CAplus.

There are fewer researches on the effect of functional group position change on device performance for highly efficient perovskite solar cell. In this work, we take pyridinesulfonic acid as an example, and study the effect of the isomeride: 2- and 3-pyridinesulfonic acid self-assembled monolayer on device performance for highly efficient perovskite solar cell. The efficiency of control device is 14.65% (Hysteresis Index = 0.31) under illumination of a simulated sunlight (AM 1.5G, 100 mW cm^-2). Through use of the 3-pyridinesulfonic acid self-assembled monolayer, the device exhibits striking improvements to reach the efficiency of 16.88% (Hysteresis Index = 0.02), which constitutes an enhancement compared to those of 2-pyridinesulfonic acid self-assembled monolayer modified device (16.54%, Hysteresis Index = 0.02). The enhanced photovoltaic performances can be attributed to the larger perovskite grain sizes, and easier passivation of electron transporting layer/perovskite interface, which promote the charge separation, transport and collection.

Applied Surface Science published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Formula: C5H5NO3S.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Funada, Atsushi published the artcileConformational Transformations of (C₁₂H₂₅NH₃⁺)(Pyridinesulfonate) in the Solid State, Related Products of pyridine-derivatives, the publication is Chemistry – An Asian Journal (2016), 11(6), 915-925, database is CAplus and MEDLINE.

The phase-transition behaviors, crystal structures, and dielec. properties of four kinds of simple 1:1 organic salts of (C₁₂H₂₅NH₃⁺)(benzenesulfonate) and (C₁₂H₂₅NH₃⁺)(pyridine sulfonates) were examined from the viewpoint of intermol. hydrogen-bonding interactions and dynamic conformational transformation in mol. assemblies. Crystals of (C₁₂H₂₅NH₃⁺)(benzenesulfonate) and (C₁₂H₂₅NH₃⁺)(3-pyridinesulfonate) were isostructural and solid-solid and solid-liquid-crystal smectic A (SmA) phase transitions were observed These two crystals formed rodlike cation-anion assemblies. However, the two salts, (C₁₂H₂₅NH₃⁺)(2-pyridinesulfonate) and (C₁₂H₂₅NH₃⁺)(4-pyridinesulfonate), formed largely bent L-shaped cation-anion conformations. Interesting conformational transformations from rodlike to L-shaped assemblies were observed in (C₁₂H₂₅NH₃⁺)(2-pyridinesulfonate) and (C₁₂H₂₅NH₃⁺)(3-pyridinesulfonate).

Chemistry – An Asian Journal published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Hanan, Emily J. published the artcileDiscovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors, Recommanded Product: 2-Bromopyridin-3-amine, the publication is Journal of Medicinal Chemistry (2012), 55(22), 10090-10107, database is CAplus and MEDLINE.

The discovery of somatic Jak2 mutations in patients with chronic myeloproliferative neoplasms has led to significant interest in discovering selective Jak2 inhibitors for use in treating these disorders. A high-throughput screening effort identified the pyrazolo[1,5-a]pyrimidine scaffold as a potent inhibitor of Jak2. Optimization of lead compounds in this chem. series for activity against Jak2, selectivity against other Jak family kinases, and good in vivo pharmacokinetic properties led to the discovery of (I). In a SET2 xenograft model that is dependent on Jak2 for growth, I demonstrated a time-dependent knock-down of pSTAT5, a downstream target of Jak2.

Journal of Medicinal Chemistry published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Recommanded Product: 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Estevez, Veronica published the artcileSynthesis of Pyridopyrimidines by Palladium-Catalyzed Isocyanide Insertion, Recommanded Product: 2-Bromopyridin-3-amine, the publication is ACS Catalysis (2014), 4(1), 40-43, database is CAplus.

A new synthetic approach to 4-aminopyrido-[2,3-d]-pyrimidines and 4-aminopyrido-[3,2-d]-pyrimidines based on palladium-catalyzed reaction of isocyanides with readily available N-(bromopyridyl)amidines is reported. The target heterocycles, e.g., I, were obtained in generally good to excellent yield. For the two regioisomeric pyrimidopyrimidines, the authors compared our approach involving oxidative addition with the analogous C-H activation protocol because both methods have been reported for the synthesis of 4-aminoquinazolines. It was found that the C-H activation protocol does not allow one to obtain the target pyridopyrimidines, but the imidoylative cross-coupling protocol provided a new entry to the synthesis of these medicinally important scaffolds.

ACS Catalysis published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Recommanded Product: 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Martinez, Thibaut published the artcileIndolizy Carbene Ligand. Evaluation of Electronic Properties and Applications in Asymmetric Gold(I) Catalysis, Synthetic Route of 91-02-1, the publication is Angewandte Chemie, International Edition (2021), 60(36), 19879-19888, database is CAplus and MEDLINE.

We report herein a new family of carbene ligands based on an indolizine-ylidene (Indolizy) moiety. The corresponding gold(I) complexes are easily obtained from the gold(I)-promoted cyclization of allenylpyridine precursors. Evaluation of the electronic properties by exptl. methods and also by DFT calculations confirms strong σ-donating and π-accepting properties of these ligands. Cationization of the gold(I) complexes generates catalytic species that trigger diverse reactions of (poly)unsaturated precursors. When armed with a methylene phosphine oxide moiety on the stereogenic center adjacent to the nitrogen atom, the corresponding bifunctional carbene ligands give rise to highly enantioselective heterocyclizations. DFT calculations brought some rationalization and highlighted the critical roles played by the phosphine oxide group and the tosylate anion in the asym. cyclization of γ-allenols.

Angewandte Chemie, International Edition published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Synthetic Route of 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Yamada, Yasuyuki published the artcileMetal-Induced Structural Switching of a Folded Quinone-Sandwiched Porphyrin, Category: pyridine-derivatives, the publication is Journal of Inorganic and Organometallic Polymers and Materials (2013), 23(1), 180-185, database is CAplus.

The authors report the synthesis of a novel quinone-sandwiched porphyrin in which two benzoquinones are connected oppositely at the meso positions of a porphyrin through rigid 3-amido 2,2′-bipyridine linkers. ¹H-NMR and single crystal x-ray analyses revealed that the quinone-sandwiched porphyrin has a folded structure in which the porphyrin unit was inserted into the two quinone moieties via π-stacking. Insertion of a Zn(II) ion into the porphyrin center induced a drastic conformational change which is resulted in coordination of the oxygen atoms of both benzoquinone moieties to the Zn-porphyrin to afford a 6-coordinated structure.

Journal of Inorganic and Organometallic Polymers and Materials published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C7H13BrSi, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Czyz, Milena L. published the artcileReductive Activation and Hydrofunctionalization of Olefins by Multiphoton Tandem Photoredox Catalysis, Related Products of pyridine-derivatives, the publication is ACS Catalysis (2021), 11(9), 5472-5480, database is CAplus.

The conversion of olefin feedstocks to architecturally complex alkanes represents an important strategy in the expedient generation of valuable mols. for the chem. and life sciences. Synthetic approaches are reliant on the electrophilic activation of unactivated olefins, necessitating functionalization with nucleophiles. However, the reductive functionalization of unactivated and less activated olefins with electrophiles remains an ongoing challenge in synthetic chem. Here, we report the nucleophilic activation of inert styrenes through a photoinduced direct single electron reduction to the corresponding nucleophilic radical anion. Central to this approach is the multiphoton tandem photoredox cycle of the iridium photocatalyst [Ir(ppy)₂(dtb-bpy)]PF₆, which triggers in situ formation of a high-energy photoreductant that selectively reduces styrene olefinic π bonds to radical anions without stoichiometric reductants or dissolving metals. This mild strategy enables the chemoselective reduction and hydrofunctionalization of styrenes to furnish valuable alkane and tertiary alc. derivatives Mechanistic studies support the formation of a styrene olefinic radical anion intermediate and a Birch-type reduction involving two sequential single electron transfers. Overall, this complementary mode of olefin activation achieves the hydrofunctionalization of less activated alkenes with electrophiles, adding value to abundant olefins as valuable building blocks in modern synthetic protocols.

ACS Catalysis published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Banks, Ronald Eric published the artcileFluorocarbon derivatives of nitrogen. Part 11. Synthesis of some 2-(trifluoromethyl)imidazo[1,2-a]pyridines from trifluoroacetonitrile, Related Products of pyridine-derivatives, the publication is Journal of Fluorine Chemistry (1984), 26(4), 499-506, database is CAplus.

The title compound (I; R = Me₃CO₂C), prepared from CF₃CN and pyridinium t-butoxycarbonylmethylide, reacts smoothly with CF₃CO₂H to give the acid (I; R = HO₂C), which was decarboxylated to I (R = H) on heating. The cyano derivative (I; R = cyano) can be obtained via treatment of CF₃CN with pyridinium cyanomethylide, which is sufficiently reactive to effect nucleophilic displacement of fluorine from pentafluoropyridine under mild conditions to give II.

Journal of Fluorine Chemistry published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Zhang, Yongliang published the artcileN-alkylation of pyridylalanine and pyridinecarboxylic acids and their use in synthesis of GnRH antagonists, Synthetic Route of 636-73-7, the publication is Tetrahedron Letters (1993), 34(23), 3659-62, database is CAplus.

A mild N-alkylation method has been developed for the synthesis of N-alkylated pyridiniumcarboxylic acids using Ag₂O-H₂O catalysis to enhance the low reactivity of pyridinecarboxylic acids. Two approaches were undertaken for the synthesis of a series of GnRH antagonists containing pyridinium moieties at the side chain: (1) incorporation of alkylated D-pyridylalanine analogs I (Boc = Me₃CO₂C; R = Me, CH₂Ph, CHMe₂, Bu) during solid phase peptide chain assembly, and (2) coupling of the N-alkylated pyridiniumcarboxylic acid to a D-lysine ε-amino group on a solid support.

Tetrahedron Letters published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C18H35NO, Synthetic Route of 636-73-7.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Stanovnik, B. published the artcileHeterocycles. CLVII. Oxidative transformations of some heterocyclic hydrazones with lead tetraacetate, Related Products of pyridine-derivatives, the publication is Croatica Chemica Acta (1977), 49(1), 135-40, database is CAplus.

2-Pyridinecarboxaldehyde phenylhydrazone (I) was treated with MeO2CCCCO2Me in presence of Pb(OAc)4 to give RCONHNPhCOMe (R = pyridyl). Without Pb(OAc)4 RCH:NNPhC(CO2Me):CHCO2Me (R = 2-pyridyl) was formed. I and H2C:CHCN in presence of Pb(OAc)4 gave the pyrazole II. 2-Pyridinecarboxaldehyde 2-pyridylhydrazone and H2C:CHCN in presence of Pb(OAc)4 gave the triazolopyridine III (R = 2-pyridyl, R1 = H). P-methoxybenzaldehyde 3-nitro-2-pyridylhydrazone similarly gave III (R = p-MeOC6H4, R1 = NO2).

Croatica Chemica Acta published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C12H10FeO4, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem