Tag: M.W=150-200

Authors Hou, P; Sun, JW; Wang, HJ; Liu, L; Zou, LW; Chen, S in ELSEVIER SCIENCE SA published article about LARGE STOKES SHIFT; TURN-ON PROBE; CELLULAR THIOLS; LIVING CELLS; REDOX; HOMOCYSTEINE; CONJUGATE; HYDRAZINE; APOPTOSIS; ROLES in [Hou, Peng; Sun, Jingwen; Wang, Haijun; Liu, Lei; Chen, Song] Qiqihar Med Univ, Coll Pharm, 333 Bukui St, Qiqihar 161006, Heilongjiang, Peoples R China; [Zou, Liwei] Shanghai Univ Tradit Chinese Med, Inst Interdisciplinary Med, 1200 Cailun Rd, Shanghai 201203, Peoples R China in 2020.0, Cited 41.0. Quality Control of Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

A novel fluorescent probe, TCF-IPY, has been designed and developed for highly selective and ratiometric detection of GSH based on the extend of the pi-conjugation system of imidazo[1,5-alpha]pyridine IPY-CHO. Upon addition of GSH, TCF-IPY displayed remarkable fluorescence variations (approximate 949-fold ratio changes) from 603 nm to 475 nm, thereby enabling GSH detection in a fine ratiometric manner. Moreover, TCF-IPY exhibited excellent selectivity toward GSH over other biologically related species including Cys and Hcy. The huge blue shifts both in absorption (259 nm) and emission spectra (128 nm), low cytotoxicity, high sensitivity (97 nM) and rapid response (240 s) of TCF-IPY make it a robust molecular tool for endogenous GSH investigation. Furthermore, TCF-IPY was also successfully used for ratiometric imaging of endogenous GSH in living MCF-7 cells and zebrafish.

Quality Control of Phenyl(pyridin-2-yl)methanone. Bye, fridends, I hope you can learn more about C12H9NO, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

HPLC of Formula: C8H9NO2. In 2019 FUTURE MED CHEM published article about CELL-PROLIFERATION; STRUCTURAL-BASIS; DRUG CANDIDATES; CHOLESTEROL; 14-ALPHA-DEMETHYLASE; INHIBITION; INSIGHTS; BINDING; CYP51; CHAIN in [Lapier, Michel; Guzman-Rivera, Daniela; Gonzalez-Herrera, Fabiola; Pesce, Barbara; Maya, Juan D.] Univ Chile, Fac Med, Inst Ciencias Biomed ICBM, Clin & Mol Pharmacol Program, Independencia 1027, Santiago 1027, Chile; [Ballesteros-Garrido, Rafael; Ballesteros, Rafael; Abarca, Belen] Univ Valencia, Fac Pharm, Dept Organ Chem, Avda Vicent Andres Estelles S-N, E-46100 Valencia, Spain; [Aguilera-Venegas, Benjamin; Moncada-Basualto, Mauricio; Olea-Azar, Claudio] Univ Chile, Fac Chem & Pharmaceut Sci, Free Rad & Antioxidants Lab, Inorgan & Analyt Dept, Santos Dumt 964, Santiago, Chile; [Moncada-Basualto, Mauricio] Univ Santiago Chile, Fac Chem & Biol, Dept Environm Sci, Santiago, Chile; [Kemmerling, Ulrike] Univ Chile, Fac Med, Inst Ciencias Biomed ICBM, Anat & Dev Biol Program, Independencia 1027, Santiago, Chile in 2019, Cited 38. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6.

Aim: To study a new series of [1,2,3] triazolo[1,5-alpha] pyridine derivatives as trypanocidal agents because current antichagasic pharmacologic therapy is only partially effective. Materials & methods: The effect of the series upon Trypanosoma cruzi epimastigotes and murine macrophages viability, cell cycle, cell death and on the metabolites of the sterol biosynthesis pathway was measured; also, docking in 14 alpha-demethylase was analyzed. Results: Compound 16 inhibits 14 alpha-demethylase producing an imbalance in the cholesterol/ergosterol synthesis pathway, as suggested by a metabolic control and theoretical docking analysis. Consequently, it prevented cell proliferation, stopping the cellular cycle at the G2/M phase, inducing cell death. Conclusion: Although the exact cell death mechanism remained elusive, this series can be used for the further rational design of novel antiparasitic molecules.

HPLC of Formula: C8H9NO2. Welcome to talk about 614-18-6, If you have any questions, you can contact Lapier, M; Ballesteros-Garrido, R; Guzman-Rivera, D; Gonzalez-Herrera, F; Aguilera-Venegas, B; Moncada-Basualto, M; Ballesteros, R; Abarca, B; Pesce, B; Kemmerling, U; Olea-Azar, C; Maya, JD or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Zn(II)-selective poly (vinyl chloride) (PVC) membrane electrode based on Schiff base ligand 2-benzoylpyridine semicarbazone as an ionophore WOS:000591188400006 published article about HEAVY-METAL IONS; SENSOR; CONSTRUCTION; CARRIER in [Suman, Shankar; Singh, Ram] Delhi Technol Univ, Dept Appl Chem, Delhi 110042, India in 2020.0, Cited 35.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Recommanded Product: 91-02-1

A new poly (vinyl chloride) (PVC) membrane electrode using 2-benzoylpyridine semicarbazone as membrane carrier with dioctylphthalate as plasticizer and sodium tetraphenylborate (NaTBP) as anion excluder has been fabricated and investigated as Zn(II)-selective electrode. Best potential response is observed for the composition PVC 30%, plasticizer 58%, NaTBP 8% and ionophore 4% (w/w). The sensor showed a linear stable response over a concentration range of 1.0 x 10(-2)-4.56 x 10(-6) M with a detection limit of 2.28 x 10(-6) M and a response time <10 s. The electrode can be used for at least six months without any divergence in potential. Bye, fridends, I hope you can learn more about C12H9NO, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 91-02-1

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Tuning acylthiourea ligands in Ru(II) catalysts for altering the reactivity and chemoselectivity of transfer hydrogenation reactions, and synthesis of 3-isopropoxy-1H-indole through a new synthetic approach WOS:000509472400005 published article about ASYMMETRIC TRANSFER HYDROGENATION; SELECTIVE HYDROGENATION; COMPLEXES SYNTHESIS; ANTICANCER ACTIVITY; REDUCTION; KETONES; NANOPARTICLES; DERIVATIVES; ALDEHYDES; QUINONES in [Sathishkumar, Pushpanathan N.; Prabha, Padinhattath Sachind; Karvembu, Ramasamy] Natl Inst Technol, Dept Chem, Tiruchirappalli 620015, India; [Bhuvanesh, Nattamai S. P.] Texas A&M Univ, Dept Chem, College Stn, TX 77842 USA in 2020.0, Cited 57.0. Recommanded Product: Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

Ru(II)-p-cymene complexes (1-3) containing picolyl based pseudo-acylthiourea ligands (L-1-L-3) were synthesized and characterized. The crystallographic study confirmed the molecular structures of all the ligands (L-1-L-3) and complex 3. The catalytic activity of the complexes was tested mainly towards TH of carbonyl compounds and nitroarenes. The influence of steric and electronic effects of the ligands on the chemoselectivity and reactivity were reported. The catalytic activity was enhanced and chemoselectivity was switched after tuning the ligands in the catalysts, compared to their corresponding unmodified Ru(II)-p-cymene complexes. The catalysis was extended to a broad range of substrates including some challenging systems like furfural, benzoylpyridine, benzoquinone, chromanone, etc. The strategy of tuning the bifunctional ligands in the catalysts for effective and selective catalysis worked nicely. Further, the catalysis was extended to one pot synthesis of 3-isopropoxyindole from 2-nitrocinnamaldehyde, the first synthetic route similar to Baeyer Emmerling indole synthesis. All the catalytic experiments exhibited high conversion and selectivity. (C) 2019 Elsevier B.V. All rights reserved.

Recommanded Product: Phenyl(pyridin-2-yl)methanone. Welcome to talk about 91-02-1, If you have any questions, you can contact Sathishkumar, PN; Prabha, PS; Bhuvanesh, NSP; Karvembu, R or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

In 2019.0 J MOL STRUCT published article about CRYSTAL-STRUCTURE; SPECTRAL CHARACTERIZATION; NICKEL(II) COMPLEXES; MOLECULAR-STRUCTURE; CU(II) COMPLEXES; SCHIFF-BASE; DNA-BINDING; HYDRAZONE; COPPER(II); DIACETYL in [Mathews, Nimya Ann; Kurup, M. R. Prathapachandra] Cochin Univ Sci & Technol, Dept Appl Chem, Kochi 682022, Kerala, India; [Jose, Anitha] Marthoma Coll, Dept Bot, Tiruvalla 689103, Kerala, India; [Kurup, M. R. Prathapachandra] Cent Univ Kerala, Sch Phys Sci, Dept Chem, Tejaswini Hills, Periye 671316, Kasaragod, India in 2019.0, Cited 40.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Application In Synthesis of Phenyl(pyridin-2-yl)methanone

A new aroylhydrazone ligand, 2-benzoylpyridine-4-methoxybenzhydrazone (BPMBH). and its two cobalt(III) complexes, [Co(BPMB)(2)]NO3 center dot 1.5H(2)O (1) and [Co(BPMB)(2)]Cl center dot 2H(2)O (2) have been synthesized and structurally characterized. The synthesized compounds are physico-chemically characterized by CHN analysis, molar conductivity, magnetic susceptibility measurements and spectroscopic techniques like MS, IR, UV and NMR. The high molar conductivity values of the complexes confirmed the presence of counter ions in the lattice of the cationic complexes. The molecular structure of the aroylhydrazone and its complexes have been resolved using single crystal XRD studies. In the solid state, the aroylhydrazone exists in the amido form as evident from the IR and XRD studies. The tridentate nature of the NNO donor aroylhydrazone was also confirmed from the IR spectral studies. XRD studies reveal that in all complexes, the tridentate aroylhydrazone coordinates to the Co(III) center via pyridine nitrogen, azomethine nitrogen and iminolate oxygen and found to possess distorted octahedral geometry. The complexes are bis-ligated cationic complexes in which chloride and nitrate ions act as counter ions. The antibacterial and antifungal activities of the aroylhydrazone and its Co(III) complexes have been screened against bacterial species Staphylococcus aureus, Enterobacter aerogenes, Bacillus subtilis, Streptococcus pyogenes, Klebsiella pneumonia, Salmonella typhi and Escherichia coli. The antifungal activity was also checked using fungi Aspergillus niger, Penicillium chrysogenum and Rhizopus oryzae. From the activity data we can infer that the metal complexes have better biological activity than the metal free ligand against the bacterial and fungal species which were tested. (C) 2018 Elsevier B.V. All rights reserved.

Application In Synthesis of Phenyl(pyridin-2-yl)methanone. Welcome to talk about 91-02-1, If you have any questions, you can contact Mathews, NA; Jose, A; Kurup, MRP or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Product Details of 614-18-6. An, JC; Liu, PP; Si, MY; Li, WH; He, P; Yang, B; Yang, GY in [An, Jichao; Liu, Peipei; Si, Mengyuan; Li, Wenhao; He, Pan; Yang, Bo; Yang, Guanyu] Zhengzhou Univ, Coll Chem, Zhengzhou 450001, Peoples R China published Practical catalytic nitration directly with commercial nitric acid for the preparation of aliphatic nitroesters in 2020, Cited 23. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6.

To pursue a sustainable and efficient approach for aliphatic nitroester preparation from alcohol, europium-triflate-catalyzed nitration, which directly uses commercial nitric acid, has been successfully developed. Gram scalability with operational ease showed its practicability.

Product Details of 614-18-6. Bye, fridends, I hope you can learn more about C8H9NO2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

I found the field of Chemistry; Physics very interesting. Saw the article New benzothiazole based copper(II) hydrazone Schiff base complexes for selective and environmentally friendly oxidation of benzylic alcohols: The importance of the bimetallic species tuned by the choice of the counterion published in 2020.0. Application In Synthesis of Phenyl(pyridin-2-yl)methanone, Reprint Addresses Gorczynski, A; Patroniak, V (corresponding author), Adam Mickiewicz Univ, Fac Chem, Uniwersytetu Poznanskiego 8, PL-61614 Poznan, Poland.. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

Green and sustainable chemistry approaches necessitate an ongoing investigation towards new, environmentally benign and selective catalysts. We have thus prepared a new benzothiazole-scaffolded hydrazone Schiff base ligand L and coordinated it with copper(II) ions leading to five different complexes, the form of which in the solid state is counterion-dependent. Nitrate, chloride and trifiate anions lead to monometallic species, whereas utilization of sulfates and tetrafluoroborates is responsible for the formation of bimetallic assemblies. The catalytic efficiency of synthesized compounds was shown in Cu-TEMPO (2,2,6,6-tetramethyl-l-piperidinoxyl) aerobic oxidation of activated alcohols resulting in good to excellent conversions and 100% selectivity to form the corresponding aldehydes. Considering the experimental results and Density Functional Theory calculations we propose two most plausible reaction mechanisms that further corroborate the enhanced activity of bimetallic species. It appears that the tridentate character of the ligand sacrifices some of the overall catalytic efficiency for the selectivity of the process. Aqueous reaction medium, low catalyst loading, air as oxidant and exclusive oxidative selectivity render these Cu ll complexes promising candidates for further improvement. (C) 2020 Elsevier B.V. All rights reserved.

Bye, fridends, I hope you can learn more about C12H9NO, If you have any questions, you can browse other blog as well. See you lster.. Application In Synthesis of Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

I found the field of Biochemistry & Molecular Biology; Biophysics very interesting. Saw the article Assessment of cytotoxic and genotoxic potentials of a mononuclear Fe(II) Schiff base complex with photocatalytic activity in Trigonella published in 2020.0. Recommanded Product: 91-02-1, Reprint Addresses Roy, S (corresponding author), Univ Burdwan, UGC Ctr Adv Studies, Dept Bot, Golapbag Campus, Burdwan 713104, W Bengal, India.. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

Background: In recent times, coordination complexes of iron in various oxidation states along with variety of ligand systems have been designed and developed for effective treatment of cancer cells without adversely affecting the normal cell and tissues of various organs. Methods: In this study, we have evaluated the mechanism of action of a Fe(II) Schiff base complex in the crop plant Trigonella foenum-graecum L. (Fenugreek) as the screening system by using morphological, cytological, biochemical and molecular approaches. Further functional characterization was performed using MCF-7 cell line and solid tumour model for the assessment of anti-tumour activity of the complex. Results: Our results indicate efficiency of the Fe(II) Schiff base complex in the induction of double strand breaks in DNA. Complex treatment clearly induced cytotoxic and genotoxic damage in Trigonella seedlings. The Fe-complex treatment caused cell cycle arrest via the activation of ATM-ATR kinase mediated DNA damage response pathway with the compromised expression of CDK1, CDK2 and CyclinB1 protein in Trigonella seedlings. In cultured MCF-7 cells, the complex induces cytotoxicity and DNA fragmentation through intracellular ROS generation. Fe-complex treatment inhibited tumour growth in solid tumour model with no additional side effects. Conclusion: The growth inhibitory and cytotoxic effects of the complex result from activation of DNA damage response along with oxidative stress and cell cycle arrest. General significance: Overall, our results have provided comprehensive information on the mechanism of action and efficacy of a Fe(II) Schiff base complex in higher eukaryotic genomes and indicated its future implications as potential therapeutic agent.

Recommanded Product: 91-02-1. Welcome to talk about 91-02-1, If you have any questions, you can contact Mahapatra, K; Ghosh, AK; De, S; Ghosh, N; Sadhukhan, P; Chatterjee, S; Ghosh, R; Sil, PC; Roy, S or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Diez-Simon, C; Eichelsheim, C; Jacobs, DM; Mumm, R; Hall, RD in ELSEVIER published article about VOLATILE COMPOUNDS; FERMENTATION; COMPONENTS; PROFILES; SAMPLE; ACID; TOOL in [Diez-Simon, Carmen; Eichelsheim, Charlotte; Hall, Robert D.] Wageningen Univ & Res, Lab Plant Physiol, Droevendaalsesteeg 1, NL-6708 PB Wageningen, Netherlands; [Diez-Simon, Carmen; Mumm, Roland; Hall, Robert D.] Netherlands Metabol Ctr, Einsteinweg 55, NL-2333 CC Leiden, Netherlands; [Mumm, Roland; Hall, Robert D.] Wageningen Univ & Res, Wageningen Plant Res Biosci, Droevendaalsesteeg 1, NL-6708 PB Wageningen, Netherlands; [Eichelsheim, Charlotte] Wageningen Univ & Res, Food Chem Lab, Bornse Weilanden 9, NL-6708 WG Wageningen, Netherlands; [Jacobs, Doris M.] Unilever Foods Innovat Ctr, Bronland 14, NL-6708 WH Wageningen, Netherlands in 2021, Cited 36. Recommanded Product: Ethyl nicotinate. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6

Fermented soy sauce is used worldwide to enhance the flavour of many dishes. Many types of soy sauce are on the market, and their differences are mostly related to the country of origin, the production process applied and the ratio of ingredients used. Consequently, several aromas, tastes, colours, and textures are obtained. Nowadays, soy sauce can also be produced without microorganisms making the process shorter and cheaper. However, flavour may be lost. We have carried out a comprehensive metabolomics analysis of volatile compounds using stir bar sorptive extraction (SBSE)-GC-MS to relate differences in volatile content to production history and origin. The results revealed major differences between fermented and non-fermented soy sauces, and a list of volatile compounds is reported as being characteristic of each type. This study was able to relate volatiles to the production process using SBSE-GC-MS and to aroma characteristics using GC-O-MS.

Welcome to talk about 614-18-6, If you have any questions, you can contact Diez-Simon, C; Eichelsheim, C; Jacobs, DM; Mumm, R; Hall, RD or send Email.. Recommanded Product: Ethyl nicotinate

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

I found the field of Chemistry very interesting. Saw the article Highly Enantioselective Direct Asymmetric Reductive Amination of 2-Acetyl-6-Substituted Pyridines published in 2021.0. SDS of cas: 91-02-1, Reprint Addresses Yamada, M (corresponding author), Takeda Pharmaceut Co Ltd, Pharmaceut Sci, Proc Chem, Osaka 5320024, Japan.. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

A highly direct asymmetric reductive amination of a variety of ketone substrates, including 2-acetyl-6-substituted pyridines, beta-keto esters, beta-keto amides, and 1-(6-methylpyridin-2yl)propan-2-one, has been disclosed for the first time (94.6% to >99.9% ee). With ammonium trifluoroacetate as the nitrogen source, various chiral corresponding primary amines were prepared in excellent enantioselectivity and conversion in the presence of a commercially available and inexpensive chiral catalyst, Ru(OAc)(2){(S)-binap}, under 0.8 MPa of hydrogen gas pressure.

SDS of cas: 91-02-1. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Yamada, M; Azuma, K; Yamano, M or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem