Tag: M.W=150-200

Filace, Fabiana published the artcileSilyl Assistance in the Intramolecular Addition of Pyridyl Radicals onto Pyridines and Quinolines, Quality Control of 39856-58-1, the publication is European Journal of Organic Chemistry (2016), 2016(10), 1891-1896, database is CAplus.

The first example of a stable acylazinium salt obtained by an intramol. acylpyridine-centered radical attack on azine nitrogen atoms is reported. Depending on the relative position of the bromo substituent on the attacking aminopyridine ring, it is possible to obtain selectively either the N-attack product or a different C-attack derivative A rationale for this pathway selectivity was obtained from quantum mech. calculations

European Journal of Organic Chemistry published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Quality Control of 39856-58-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Bell, Colin Frank published the artcileComplexes between pyridine-2-aldehyde-2′-pyridylhydrazone and the platinum metals. I. Rhodium, Formula: C11H10N4, the publication is Inorganic Chemistry (1968), 7(2), 325-9, database is CAplus.

Mono, bis, and tris complexes of Rh(III) and pyridine-2-aldehyde-2′-pyridylhydrazone have been prepared and studied. In all three, the H atom of the imino group of the ligand shows marked acidity associated with coordination to a tripos. metal. The ligand is tridentate in the mono and bis complexes but bidentate in the tris complex. Possible geometrical isomers of this are discussed and its probable structure is described. 17 references.

Inorganic Chemistry published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Formula: C11H10N4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Bell, Colin Frank published the artcileComplexes between pyridine-2-carboxaldehyde 2′-pyridylhydrazone and the platinum metals. II. Iridium, Synthetic Route of 2215-33-0, the publication is Inorganic Chemistry (1969), 8(1), 161-3, database is CAplus.

Aqueous (NH4)3(IrCl6) was refluxed with pyridine-2-carboxaldehyde 2′-pyridylhydrazone (HL) in CHCl3 to form [Ir(HL)3]. Also prepared were [IrCl2(HL)]ClO4.2H2O, [IrCl2pyL], and [IrCl3py(HL)] (I), where I is the 1,2,6-isomer. The complexes were characterized by absorption spectra, ir. spectra, and conductance measurements. HL appears to behave as a bidentate ligand in the complexes except in the case of [IrCl2pyL] where it is tridentate.

Inorganic Chemistry published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Synthetic Route of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Das, Rudra Narayan published the artcilePredictive in silico Modeling of Ionic Liquids toward Inhibition of the Acetyl Cholinesterase Enzyme of Electrophorus electricus: A Predictive Toxicology Approach, Synthetic Route of 17281-59-3, the publication is Industrial & Engineering Chemistry Research (2014), 53(2), 1020-1032, database is CAplus.

Chems. are the essential components of the industry for maneuvering the required need of the living ecosystem. Ionic liquids are a group of promising novel chems. with potential usefulness toward various industrial applications, although they are not entirely devoid of hazardous outcomes. The present study is an attempt to investigate the chem. attributes of a wide variety of 292 ionic liquids toward their inhibitory potential of acetyl cholinesterase enzyme of elec. eel through the development of predictive regression and classification-based quant. math. models in the light of the OECD guidelines. Mol. docking studies have addnl. corroborated the results. Hydrophilicity, hydrophobicity, branching, and pos. charged N-species were observed to be the major chem. contributors to such toxicity. The docking studies chiefly portrayed the π-cationic type interaction of the cationic N⁺ atom with the Phe 288, Phe 290, and Trp 23 residues of the acyl binding pocket to be responsible for enzyme inhibition.

Industrial & Engineering Chemistry Research published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Synthetic Route of 17281-59-3.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Ramya, G. published the artcileInvestigations on pyridine-3-sulfonic acid doped polyaniline and polypyrrole: Metal loading through dopant molecules, Safety of Pyridine-3-sulfonic acid, the publication is Reactive & Functional Polymers (2008), 68(3), 701-709, database is CAplus.

Polyniline and polypyrrole were chem. and electrochem. synthesized in presence of pyridine-3-sulfonic acid. These conducting polymers were characterized by FT-IR, UV-vis, XRD, TGA and SEM techniques. Polyaniline showed a conductivity of 4 × 10^-4 S/cm while polypyrrole exhibited a conductivity of 6.2 × 10^-2 S/cm. The presence of pyridine ring in the dopant enabled the polymers to anchor Pd/or PdO through which the composite can work as catalytic material.

Reactive & Functional Polymers published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Safety of Pyridine-3-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Brook, David J. R. published the artcileStrong ferromagnetic metal-ligand exchange in a nickel bis(3,5-dipyridylverdazyl) complex, Recommanded Product: 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, the publication is Chemical Communications (Cambridge, United Kingdom) (2010), 46(35), 6590-6592, database is CAplus and MEDLINE.

A new 1,5-dipyridyl verdazyl, synthesized from the corresponding dipyridyl hydrazone, coordinates nickel(II) to form a structurally characterized, pseudooctahedral complex analogous to Ni(terpy)₂²⁺. The unusually short Ni-verdazyl distance results in strong ferromagnetic exchange (J_Ni-rad = +300, J_rad-rad = +160 cm^-1) between all three paramagnetic species along with a metal-ligand charge transfer band in the electronic spectrum.

Chemical Communications (Cambridge, United Kingdom) published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Recommanded Product: 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Grimstrup, Marie published the artcileNovel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2, Safety of (6-Amino-5-methylpyridin-3-yl)boronic acid, the publication is Bioorganic & Medicinal Chemistry Letters (2010), 20(3), 1181-1185, database is CAplus and MEDLINE.

Structure-activity relationships have been established by exploring the eastern and western side of 5-thiazolyleacetic acids as CRTH2 (chemoattractant receptor-homologous mol. expressed on Th2 cells) antagonists. Benzhydryl motifs in the 2-position of the thiazole was found to be most advantageous. The 4-thiazole position should either carry 3- or 4-fluorophenyl rings or a 4-pyridyl suitably substituted in the flanking 2-position. Several compounds with single digit nanomolar binding affinity and full antagonistic efficacy for human CRTH2 receptor were obtained. The compound series display a good PK profile and selectivity over a large number of other targets.

Bioorganic & Medicinal Chemistry Letters published new progress about 1032759-01-5. 1032759-01-5 belongs to pyridine-derivatives, auxiliary class Boronic acid and ester,Boronic acid and ester, name is (6-Amino-5-methylpyridin-3-yl)boronic acid, and the molecular formula is C6H9BN2O2, Safety of (6-Amino-5-methylpyridin-3-yl)boronic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Henrick, C. A. published the artcilePyridinium ylides in synthesis. II. Acylation and the synthesis of β-dicarbonyl compounds, Safety of 1-(Cyanomethyl)pyridin-1-ium chloride, the publication is Australian Journal of Chemistry (1967), 20(11), 2455-65, database is CAplus.

The acylation of N-pyridinium ylides with acid chlorides or anhydrides yields C-acylated ylides which may be reductively cleaved to yield β-diketones or β-keto esters, depending on the starting materials. The uv, ir, and N.M.R. spectra of the ylides are discussed. 34 references.

Australian Journal of Chemistry published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Safety of 1-(Cyanomethyl)pyridin-1-ium chloride.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Patel, Nitinchandra D. published the artcileEffective BI-DIME Ligand for Suzuki-Miyaura Cross-Coupling Reactions in Water with 500 ppm Palladium Loading and Triton X, Product Details of C6H8BNO3, the publication is Asian Journal of Organic Chemistry (2017), 6(9), 1285-1291, database is CAplus.

An efficient, sustainable, and broadly applicable procedure has been developed for Suzuki-Miyaura cross-coupling reactions in environmentally benign solvent (water) by employing as little as 500 ppm Pd(OAc)₂ with a monophosphorus BI-DIME ligand in the presence of inexpensive and com. available nonionic surfactant Triton X-100. This method was applied to a broad range of functionalized reaction partners, thereby affording excellent yields of the coupling products, including active pharmaceutical ingredients (APIs). An interesting kinetic study by using reaction calorimetry is also presented, which describes the effect of reaction parameters that enabled the low catalyst loading.

Asian Journal of Organic Chemistry published new progress about 1351413-50-7. 1351413-50-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester,Amide,Pyridine,Boronic Acids,Boronic acid and ester, name is (1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronic acid, and the molecular formula is C6H8BNO3, Product Details of C6H8BNO3.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Costa, Marta published the artcileSynthesis of 3-aminochromenes: the Zincke reaction revisited, Product Details of C7H7ClN2, the publication is Tetrahedron (2014), 70(33), 4869-4875, database is CAplus.

3-(Amino)coumarin derivatives and 2-(imino)-3-chromenamine derivatives were efficiently prepared by a Zincke-reaction-ring-opening reaction of the corresponding 2H-chromene-3-pyridinium chlorides using N-methylpiperazine. This methodol. unravels the marked potential of pyridinium salts as protective groups for primary amines. These scaffolds can be considered important building blocks for N-[7-[[3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-α-L–lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-(3-methyl-2-buten-1-yl)benzamide (novobiocin) analogs and similar heterocyclic compounds The synthesis of the target compounds was achieved by a cyclization (heterocyclization, Zincke reaction) of 2-hydroxybenzoic acid derivatives with 1-(cyanomethyl)pyridinium chloride. The title compounds thus formed included 1-(2-imino-2H-1-benzopyran-3-yl)pyridinium chloride derivatives (chromene-imine derivatives) and 1-(2-oxo-2H-1-benzopyran-3-yl)pyridinium chloride derivatives (coumarin derivatives). These compounds was intermediates for 3-amino-2H-1-benzopyran-2-one derivatives (amine-coumarin derivatives) and 2-(imino)-2H-1-benzopyran-3-amine derivatives

Tetrahedron published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Product Details of C7H7ClN2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem