Tag: M.W=150-200

An article Towards blue emitting monocyclometalated gold(iii) complexes – synthesis, characterization and photophysical investigations WOS:000472454100034 published article about CYCLOMETALATED ALKYNYLGOLD(III) COMPLEXES; RAY CRYSTAL-STRUCTURE; LIVED EXCITED-STATES; IRIDIUM COMPLEXES; ORGANOGOLD(III) COMPLEXES; EXCITATION-ENERGIES; GOLD COMPLEXES; DEVICES; EFFICIENCY; EMISSION in [Bachmann, Michael; Fessler, Reto; Blacque, Olivier; Venkatesan, Koushik] Univ Zurich, Dept Chem, Winterthurerstr 190, CH-8057 Zurich, Switzerland; [Venkatesan, Koushik] Macquarie Univ, Dept Mol Sci, Sydney, NSW 2109, Australia in 2019.0, Cited 78.0. Name: Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

Blue emitting phosphorescent materials with high efficiency and high stability are a key requirement for the wider adoption of organic light emitting devices (OLEDs). In order to achieve triplet derived emission at the higher energy region of the electromagnetic spectrum, a series of neutral, monocyclometalated gold(iii) complexes with trifluoromethyl and trifluoromethoxy functionalized 2-phenylpyridine (ppy) derivatives, 2-anilinopyridine (apy), 2-benzoylpyridine (bpy) and 2-benzylpyridine (bepy), as the cyclometalating framework and diaryl or monoaryl alkyne as ancillary ligands have been designed and synthesized. Extensive photophysical and chemical characterization by various nuclear magnetic resonance spectroscopy techniques, elemental analysis and single crystal X-ray diffraction studies of selected compounds was carried out to confirm the structural and the chemical identity of the complexes. The emission wavelength maxima of the complexes appear in the blue/sky blue region of the electromagnetic spectrum. Detailed photophysical investigations revealed that the different emission properties of the complexes are predominantly dictated by the electronic properties of the cyclometalating ligand. The interesting photoluminescence properties along with the facile synthetic access makes this a promising concept to obtain highly suitable blue emitting gold(iii) complexes.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Bachmann, M; Fessler, R; Blacque, O; Venkatesan, K or concate me.. Name: Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Diez-Simon, C; Eichelsheim, C; Jacobs, DM; Mumm, R; Hall, RD in [Diez-Simon, Carmen; Eichelsheim, Charlotte; Hall, Robert D.] Wageningen Univ & Res, Lab Plant Physiol, Droevendaalsesteeg 1, NL-6708 PB Wageningen, Netherlands; [Diez-Simon, Carmen; Mumm, Roland; Hall, Robert D.] Netherlands Metabol Ctr, Einsteinweg 55, NL-2333 CC Leiden, Netherlands; [Mumm, Roland; Hall, Robert D.] Wageningen Univ & Res, Wageningen Plant Res Biosci, Droevendaalsesteeg 1, NL-6708 PB Wageningen, Netherlands; [Eichelsheim, Charlotte] Wageningen Univ & Res, Food Chem Lab, Bornse Weilanden 9, NL-6708 WG Wageningen, Netherlands; [Jacobs, Doris M.] Unilever Foods Innovat Ctr, Bronland 14, NL-6708 WH Wageningen, Netherlands published Stir bar sorptive extraction of aroma compounds in soy sauce: Revealing the chemical diversity in 2021, Cited 36. Category: pyridine-derivatives. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6.

Fermented soy sauce is used worldwide to enhance the flavour of many dishes. Many types of soy sauce are on the market, and their differences are mostly related to the country of origin, the production process applied and the ratio of ingredients used. Consequently, several aromas, tastes, colours, and textures are obtained. Nowadays, soy sauce can also be produced without microorganisms making the process shorter and cheaper. However, flavour may be lost. We have carried out a comprehensive metabolomics analysis of volatile compounds using stir bar sorptive extraction (SBSE)-GC-MS to relate differences in volatile content to production history and origin. The results revealed major differences between fermented and non-fermented soy sauces, and a list of volatile compounds is reported as being characteristic of each type. This study was able to relate volatiles to the production process using SBSE-GC-MS and to aroma characteristics using GC-O-MS.

About Ethyl nicotinate, If you have any questions, you can contact Diez-Simon, C; Eichelsheim, C; Jacobs, DM; Mumm, R; Hall, RD or concate me.. Category: pyridine-derivatives

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

I found the field of Energy & Fuels very interesting. Saw the article Stability of the oxidized form of RuLL ‘(NCS)(2) dyes in acetonitrile in the presence of water and pyridines – Why the dye-sensitized solar cell electrolyte should be dry published in 2019. SDS of cas: 614-18-6, Reprint Addresses Lund, T (corresponding author), Roskilde Univ, Dept Sci & Environm, Roskilde, Denmark.. The CAS is 614-18-6. Through research, I have a further understanding and discovery of Ethyl nicotinate

The detrimental effect of electrolyte water contamination on the light-soaking lifetime of Dye-sensitized Solar Cells (DSCs) prepared with RuLL'(NCS)(2) dyes and N-additives like 4-tert-butylpyridine (TBP) is not well understood. A new explanation is presented based on investigation of the stability of the ruthenium(III) complexes Ru(bipy)(2)(NCS)(2)(+) (1(+)) and RuLL'(NCS)(2)(+) (L = 4,4′-dicarboxy-2,2′-bipyridine, L’ = 4,4′-nonyl-2,2′-bipyridine) (Z907(+)) in acetonitrile in the presence of water and pyridines covering a large variation in basicity. 1(+) reacts with small amounts of water in the acetonitrile containing a pyridine base (X) according to the overall reaction: 6Ru(bipy)(2)(NCS)(2)(+) + 4H(2)O + 8X -> 5Ru(bipy)(2)(NCS)(2) + Ru(bipy)(2)(NCS)(CN) + SO42- + 8XH(+). The reaction mechanism of 1(+) (and Z907(+)) is proposed to be initiated by an attack of OH- giving Ru(bipy)(2)(NCS)(NCS-OH). The stronger the base the faster the reaction. Extrapolating the life time of Z907(+) to a typical TBP concentration of 0.5 M in the DSC gives a degradation rate around 7 s(-1). Z907(+) bound to a layer of nano crystalline TiO2 surface reacted fast too, when inserted in an acetonitrile solution containing 4-tentbutylpyridine. In a wet electrolyte, containing more than 500 mM of water the light-soaking lifetime of a DSC prepared with Z907 is predicted to be about 10 days at out-door light soaking conditions, whereas trace amounts of water (< 25 mM) in a dry electrolyte is used up by consumption of only 10% of the Z907 in a typical DSC. Therefore, the DSC is expected to have a long light-soaking lifetime with a dry electrolyte. About Ethyl nicotinate, If you have any questions, you can contact Lund, T; Hansen, PE; Josephsen, J; Krake, NJ; Mortensen, J or concate me.. SDS of cas: 614-18-6

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Name: Ethyl nicotinate. Gu, YF; Zhang, Y; Yue, FL; Li, ST; Zhang, ZQ; Li, J; Bai, X in [Gu, Yi-Fei; Zhang, Yue; Zhang, Zhuo-qi; Bai, Xu] Jilin Univ, Sch Pharmaceut Sci, Ctr Combinatorial Chem & Drug Discovery, 1266 Fujin Rd, Changchun 130021, Peoples R China; [Yue, Feng-li; Li, Shao-tong; Li, Jing] Jilin Univ, Dept Pharmacol, Coll Basic Med Sci, Changchun 130021, Peoples R China published Synthesis of Novel 2-(Pyridin-2-yl) Pyrimidine Derivatives and Study of Their Anti-Fibrosis Activity in 2020, Cited 34. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6.

A pyrimidine moiety exhibiting a wide range of pharmacological activities has been employed in the design of privileged structures in medicinal chemistry. To prepare libraries of novel heterocyclic compounds with potential biological activities, a series of novel 2-(pyridin-2-yl) pyrimidine derivatives were designed, synthesized and their biological activities were evaluated against immortalized rat hepatic stellate cells (HSC-T6). Fourteen compounds were found to present better anti-fibrotic activities than Pirfenidone and Bipy55 ‘ DC. Among them, compounds ethyl 6-(5-(p-tolylcarbamoyl)pyrimidin-2-yl)nicotinate (12m) and ethyl 6-(5-((3,4-difluorophenyl)carbamoyl)pyrimidin-2-yl)nicotinate (12q) show the best activities with IC50 values of 45.69 mu M and 45.81 mu M, respectively. Furthermore, the study of anti-fibrosis activity was evaluated by Picro-Sirius red staining, hydroxyproline assay and ELISA detection of Collagen type I alpha 1 (COL1A1) protein expression. Our study showed that compounds 12m and 12q effectively inhibited the expression of collagen, and the content of hydroxyproline in cell culture medium in vitro, indicating that compounds 12m and 12q might be developed the novel anti-fibrotic drugs.

Name: Ethyl nicotinate. About Ethyl nicotinate, If you have any questions, you can contact Gu, YF; Zhang, Y; Yue, FL; Li, ST; Zhang, ZQ; Li, J; Bai, X or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recommanded Product: 91-02-1. In 2020.0 DALTON T published article about NI-II COMPLEXES; MOLECULAR-STRUCTURE; HYDROLYSIS; MECHANISM; LIGANDS; ESTERS; DRUGS; COBALT(III); DERIVATIVES; KINETICS in [Dasgupta, Sanchari; Karim, Suhana; Das, Debasis] Univ Calcutta, Dept Chem, 92 APC Rd, Kolkata 700009, India; [Banerjee, Saswati; Saha, Moumita; Saha, Krishna Das] CSIR Indian Inst Chem Biol, Canc Biol & Inflammatory Disorder Div, 4 Raja SC Mullick Rd, Kolkata 700032, India in 2020.0, Cited 48.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

Three asymmetric tridentate acyl hydrazone Schiff base ligands namely L1, L2 and L3 were prepared via condensation of 4-methoxybenzohydrazide with picolinaldehyde, 1-(pyridin-2-yl)ethanone and phenyl(pyridin-2-yl)methanone respectively. Three bio-relevant mononuclear zinc(ii) complexes [Zn(L1)Cl-2]2H(2)O (1), [Zn(L2)Cl-2] (2) and [Zn(L3)Cl-2] (3) were synthesized by treatment of zinc(ii) chloride with the corresponding Schiff base ligands and characterised by the usual physicochemical techniques. The solid state structures of complexes 1 and 3 were evaluated by single crystal X-ray analysis. All complexes were able to hydrolyse the P-O bond of the phosphate monoester in 90% (v/v) DMSO-water medium using 4-nitrophenylphosphate (4-NPP) as the model substrate and the trend in their activity is 1 approximate to 2 > 3. On considering the highly efficient hydrolysis properties, complexes 1-3 were tested as potential therapeutic agents for cancer using HCT116 (human colorectal carcinoma), HepG2 (human hepatocellular carcinoma) and A549 (human non-small lung carcinoma) cells. Complex 2 showed the highest IC50 values for anti-cancer activity towards all three cell lines among the three complexes and complex 3 showed the least activity as observed in the phosphatase activity study. The internucleosomal degradation of DNA during apoptosis can be detected by cell death detection ELISA. DNA fragmentation that leads to cell death was examined and when induced by complex 2 in HepG2 cells a significant level of DNA fragmentation was observed at regular intervals of time.

Recommanded Product: 91-02-1. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Dasgupta, S; Karim, S; Banerjee, S; Saha, M; Saha, KD; Das, D or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

COA of Formula: C12H9NO. Recently I am researching about ONE-POT SYNTHESIS; N-TOSYLHYDRAZONES; CATALYZED TRANSANNULATION; ASYMMETRIC HYDROGENATION; ETHYL DIAZOACETATE; C(SP(3))-H BONDS; DIAZO-COMPOUNDS; ARYLATION; DISCOVERY; NITRILES, Saw an article supported by the NSFCNational Natural Science Foundation of China (NSFC) [21302095]; Jiangsu Provincial NSF [BK20130924]; Nanjing Tech University. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Dong, C; Wang, X; Pei, ZB; Sheno, RW. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

Pyridotriazoles are utilized as robust building blocks to access alpha-secondary and alpha-tertiary pyridines via the development of a simple yet practically useful metal-free denitrogenative C-C cross-coupling with boronic acids. The reaction shows a high level of functional tolerance, broad substrate scope, and facile scalability. The synthetic potential of the method is demonstrated by the strurctural modification of a bioactive molecule and concise synthesis of pheniramine analogs.

COA of Formula: C12H9NO. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Dong, C; Wang, X; Pei, ZB; Sheno, RW or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recommanded Product: Phenyl(pyridin-2-yl)methanone. In 2020 ANGEW CHEM INT EDIT published article about OLD YELLOW ENZYME; COMBINING PHOTOCATALYSIS; BIOCATALYTIC REDUCTION; RADICALS; BOND; DISSOCIATION; REDOX; HETEROCYCLES; BIOREDUCTION; COMPLEXES in [Nakano, Yuji; Black, Michael J.; Meichan, Andrew J.; Sandoval, Braddock A.; Chung, Megan M.; Biegasiewicz, Kyle F.; Hyster, Todd K.] Princeton Univ, Dept Chem, Princeton, NJ 08544 USA; [Zhu, Tianyu] CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA; [Nakano, Yuji] Monash Univ, Monash Inst Pharmaceut Sci, Parkville, Vic 3052, Australia; [Biegasiewicz, Kyle F.] Arizona State Univ, Sch Mol Sci, Tempe, AZ 85287 USA in 2020, Cited 61. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

Flavin-dependent ‘ene’-reductases (EREDs) are highly selective catalysts for the asymmetric reduction of activated alkenes. This function is, however, limited to enones, enoates, and nitroalkenes using the native hydride transfer mechanism. Here we demonstrate that EREDs can reduce vinyl pyridines when irradiated with visible light in the presence of a photoredox catalyst. Experimental evidence suggests the reaction proceeds via a radical mechanism where the vinyl pyridine is reduced to the corresponding neutral benzylic radical in solution. DFT calculations reveal this radical to be dynamically stable, suggesting it is sufficiently long-lived to diffuse into the enzyme active site for stereoselective hydrogen atom transfer. This reduction mechanism is distinct from the native one, highlighting the opportunity to expand the synthetic capabilities of existing enzyme platforms by exploiting new mechanistic models.

Recommanded Product: Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Nakano, Y; Black, MJ; Meichan, AJ; Sandoval, BA; Chung, MM; Biegasiewicz, KF; Zhu, TY; Hyster, TK or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Product Details of 614-18-6. Authors Wang, XJ; Guo, MY; Song, HL; Meng, Q; Guan, XS in ELSEVIER SCI LTD published article about in [Wang, Xiaojun; Guo, Mengyao; Song, Huanlu; Meng, Qi] Beijing Technol & Business Univ BTBU, Beijing Adv Innovat Ctr Food Nutr & Human Hlth, Beijing Res Ctr Food Addit Engn Technol, Lab Mol Sensory Sci, Beijing 100048, Peoples R China; [Guan, Xiaosheng] J & X Technol Shanghai Co Ltd, Room 1034,1599 Jungong Rd, Shanghai 200438, Peoples R China in 2021, Cited 28. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6

Activity of odor compounds of soy sauces has not been fully determined so far. Herein, a new switchable GC/ GC x GC-olfactometry-mass spectrometry system for simultaneous GC x GC-MS analysis and sniffing of each odor-active substance through a single injection was used for the aroma extract dilution analysis of five regular high-salt liquid-state soy sauces (HLS). Methional, maltol, guaiacol, 4-ethylguaiacol, 2-acetylpyrrole, 2-acetylfuran, 2-phenylethanol, and 4-hydroxy-2,5-dimethyl-3(2H)-furanone showed high flavor dilution (FD) factors. The FD factors of all odor-active compounds in different odor attributes were summed up (score) to evaluate the odor characteristics of the samples. Cooked potato-like odor was the most important characteristic. The difference in the odor characteristics were mainly reflected in the balance of caramel-like/sweet, roasted/roasted nut-like, spicy/burnt, and unpleasant odor intensity; the fruity odor intensity was the weakest. This study will provide a better understanding of the odor characteristics and key odor-active compounds in Chinese regular commercial HLS.

Product Details of 614-18-6. About Ethyl nicotinate, If you have any questions, you can contact Wang, XJ; Guo, MY; Song, HL; Meng, Q; Guan, XS or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Name: Ethyl nicotinate. In 2021 SCI REP-UK published article about PREDICTION; MOLECULES in [Zeng, Ruolan; Deng, Jiyong; Dang, Limin; Yu, Xinliang] Hunan Inst Engn, Hunan Prov Key Lab Environm Catalysis & Waste Reg, Coll Mat & Chem Engn, Xiangtan 411104, Hunan, Peoples R China in 2021, Cited 23. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6.

A three-descriptor quantitative structure-activity/toxicity relationship (QSAR/QSTR) model was developed for the skin permeability of a sufficiently large data set consisting of 274 compounds, by applying support vector machine (SVM) together with genetic algorithm. The optimal SVM model possesses the coefficient of determination R-2 of 0.946 and root mean square (rms) error of 0.253 for the training set of 139 compounds; and a R-2 of 0.872 and rms of 0.302 for the test set of 135 compounds. Compared with other models reported in the literature, our SVM model shows better statistical performance in a model that deals with more samples in the test set. Therefore, applying a SVM algorithm to develop a nonlinear QSAR model for skin permeability was achieved.

About Ethyl nicotinate, If you have any questions, you can contact Zeng, RL; Deng, JY; Dang, LM; Yu, XL or concate me.. Name: Ethyl nicotinate

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Product Details of 614-18-6. Rechitskaya, ED; Kuratieva, NV; Lider, EV; Eremina, JA; Klyushova, LS; Eltsov, IV; Kostin, GA in [Rechitskaya, E. D.; Kuratieva, N., V; Lider, E., V; Eremina, J. A.; Kostin, G. A.] Nikolaev Inst Inorgan Chem SB RAS, Lavrentieva 3, Novosibirsk, Russia; [Rechitskaya, E. D.; Kuratieva, N., V; Lider, E., V; Eremina, J. A.; Eltsov, I., V; Kostin, G. A.] Novosibirsk State Univ, Pirogova 2, Novosibirsk, Russia; [Klyushova, L. S.] Inst Mol Biol & Biophys, Subdiv FRC FTM, 2-12 Timakova Str, Novosibirsk 630060, Russia; [Klyushova, L. S.] Sci Inst Clin & Expt Lymphol, Branch ICG SB RAS, 2 Timakova Str, Novosibirsk 630117, Russia published Tuning of cytotoxic activity by bio-mimetic ligands in ruthenium nitrosyl complexes in 2020, Cited 37. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6.

Three novel ruthenium nitrosyl complexes [Ru(NO)Cl-3(InicMe)(2)] (1b), [RuNOCl3(NicEt)(2)] (1c) and [RuNOCl3(NicMe)(2)] (1d) (InicMe = methyl isonicotinate, NicEt = ethyl nicotinate, NicMe = methyl nicotinate)were prepared and crystal structure of the complexes were determined by single crystal XRD analysis. In all complexes, the organic ligands are coordinated by a pyridine nitrogen atom and located in trans-position each to other and in cis-position to NO group. In the crystal package of all compounds stacking interactions of two types were determined: pi(arene)-pi(arene) and pi(COO)-pi(arene) stacking. Finally, cytotoxicity of the compounds was tested on Hep2 and HepG2 cell lines. In the set of similar compounds mer-[RuNO(L)(2)Cl-3] (L = Py, gamma-Pic, beta-Pic, Inic-Alk, Nic-Alk), complexes with iso-nicotinic acid esters are the most toxic, while nicotinic acid derivatives are less toxic and compared with pyridine complex. (C) 2020 Elsevier B.V. All rights reserved.

Product Details of 614-18-6. About Ethyl nicotinate, If you have any questions, you can contact Rechitskaya, ED; Kuratieva, NV; Lider, EV; Eremina, JA; Klyushova, LS; Eltsov, IV; Kostin, GA or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem