Tag: M.W=150-200

An article Practical catalytic nitration directly with commercial nitric acid for the preparation of aliphatic nitroesters WOS:000565016900005 published article about RECYCLABLE CATALYSTS; ALKYL NITRATES; THERAPY in [An, Jichao; Liu, Peipei; Si, Mengyuan; Li, Wenhao; He, Pan; Yang, Bo; Yang, Guanyu] Zhengzhou Univ, Coll Chem, Zhengzhou 450001, Peoples R China in 2020, Cited 23. Quality Control of Ethyl nicotinate. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6

To pursue a sustainable and efficient approach for aliphatic nitroester preparation from alcohol, europium-triflate-catalyzed nitration, which directly uses commercial nitric acid, has been successfully developed. Gram scalability with operational ease showed its practicability.

Quality Control of Ethyl nicotinate. About Ethyl nicotinate, If you have any questions, you can contact An, JC; Liu, PP; Si, MY; Li, WH; He, P; Yang, B; Yang, GY or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Quality Control of Phenyl(pyridin-2-yl)methanone. I found the field of Chemistry very interesting. Saw the article Engineering an alcohol dehydrogenase with enhanced activity and stereoselectivity toward diaryl ketones: reduction of steric hindrance and change of the stereocontrol element published in 2020.0, Reprint Addresses Shao, L (corresponding author), Shanghai Univ Med & Hlth Sci, Microbial Pharmacol Lab, 279 Zhouzhu Highway,Pudong New Area, Shanghai 201318, Peoples R China.; Shao, L (corresponding author), Shanghai Inst Pharmaceut Ind, State Key Lab New Drug & Pharmaceut Proc, 285 Gebaini Rd, Shanghai 200040, Peoples R China.. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone.

Steric hindrance in the binding pocket of an alcohol dehydrogenase (ADH) has a great impact on its activity and stereoselectivity simultaneously. Due to the subtle structural difference between two bulky phenyl substituents, the asymmetric synthesis of diaryl alcohols by bioreduction of diaryl ketones is often hindered by the low activity and stereoselectivity of ADHs. To engineer an ADH with practical properties and to investigate the molecular mechanism behind the asymmetric biocatalysis of diaryl ketones, we engineered an ADH from Lactobacillus kefiri (LkADH) to asymmetrically catalyse the reduction of 4-chlorodiphenylketones (CPPK), which are not catalysed by the wild type (WT) enzyme. Mutants seq1-seq5 with gradually increased activity and stereoselectivity were obtained through iterative shrinking mutagenesis. The final mutant seq5 (Y190P/I144V/L199V/E145C/M206F) demonstrated the highest activity and excellent stereoselectivity of >99% ee. Molecular simulation analyses revealed that mutations may enhance the activity by eliminating steric hindrance, inducing a more open binding loop and constructing more noncovalent interactions. The pro-R pose of CPPK with a halogen bond formed a pre-reaction conformation more easily than the pro-S pose, resulting in the high ee of (R)-CPPO in seq5. Moreover, different halogen bonds formed due to the different positions of chlorine substituents, resulting in opposite substrate binding orientation and stereoselectivity. Therefore, the stereoselectivity of seq5 was inverted toward ortho- rather than para-chlorine substituted ketones. These results indicate that the stereocontrol element of LkADH was changed to recognise diaryl ketones after steric hindrance was eliminated. This study provides novel insights into the role of steric hindrance and noncovalent bonds in the determination of the activity and stereoselectivity of enzymes, and presents an approach producing key intermediates of chiral drugs with practical potential.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Wu, K; Yang, ZJ; Meng, XG; Chen, R; Huang, JK; Shao, L or concate me.. Quality Control of Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recently I am researching about PHOTOREDOX-CATALYSIS; FUNCTIONALIZATION; ALPHA; AMIDOALKYLATION; ETHERS, Saw an article supported by the National University of SingaporeNational University of Singapore; Ministry of Education of SingaporeMinistry of Education, Singapore [MOE2017-T2-2-081]; GSK-EDB [R-143-000-687-592]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21702142, 21871205]. Name: Phenyl(pyridin-2-yl)methanone. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Xu, JH; Wu, WB; Wu, J. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

Ortho-alkylated and ortho-acylated pyridines have been conveniently synthesized from pyridine N-oxides and alkynes under visible-light-mediation in a metal-free manner. The alkynes served as both alkylating and acylating agents via switching between anaerobic and aerobic conditions. The overall strategy accommodates a broad scope of substituted pyridine N-oxides and alkynes, with excellent regioselectivity in a number of cases.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Xu, JH; Wu, WB; Wu, J or concate me.. Name: Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

SDS of cas: 614-18-6. I found the field of Chemistry very interesting. Saw the article Azine Activation via Silylium Catalysis published in 2021, Reprint Addresses List, B (corresponding author), Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany.. The CAS is 614-18-6. Through research, I have a further understanding and discovery of Ethyl nicotinate.

Practical, efficient, and general methods for the diversification of N-heterocycles have been a recurrent goal in chemical synthesis due to the ubiquitous influence of these motifs within bioactive frameworks. Here, we describe a direct, catalytic, and selective functionalization of azines via silylium activation. Our catalyst design enables mild conditions and a remarkable functional group tolerance in a one-pot setup.

About Ethyl nicotinate, If you have any questions, you can contact Obradors, C; List, B or concate me.. SDS of cas: 614-18-6

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Recognition of Thiols in Living Cells and Zebrafish Using an Imidazo[1,5-alpha]pyridine-Derivative Indicator WOS:000488830500120 published article about LARGE STOKES SHIFT; FLUORESCENT-PROBE; SELECTIVE DETECTION; CYSTEINE; GLUTATHIONE; SENSOR; HOMOCYSTEINE; ROLES in [Chen, Song; Hou, Peng; Sun, Jingwen; Wang, Haijun; Liu, Lei] Qiqihar Med Univ, Coll Pharm, Qiqihar 161006, Peoples R China in 2019.0, Cited 35.0. Safety of Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

A new cyan fluorescent probe, MIPY-DNBS, using an imidazo[1,5-alpha]pyridine derivative as the fluorophore and 2,4-dinitrobenzensufonate as the recognition site for the selective detection of thiols (Cys, GSH, and Hcy), was designed and synthesized. Probe MIPY-DNBS exhibited a 172 nm Stokes shift, a fast response time (400 s), low cytotoxicity, low detection limits (12.7 nM for Cys), and excellent selectively in the detection of thiols. In addition, MIPY-DNBS was successfully applied to imaging thiols in living MCF-7 cells and zebrafish.

Safety of Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Chen, S; Hou, P; Sun, JW; Wang, HJ; Liu, L or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recommanded Product: 91-02-1. Recently I am researching about ASYMMETRIC TRANSFER HYDROGENATION; LIGAND; EXTRACTION; SEPARATION; BEARING; ENANTIOSELECTIVITY; PALLADIUM; ACTINIDES, Saw an article supported by the . Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Wang, LD; Liu, TT. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

The transfer hydrogenation of ketones catalyzed by transition metal complexes has attracted much attention. A series of ruthenium(11) complexes bearing 2,6-bis(5,6-dialkyl-1,2,4-triazin-3-yl)pyridine ligands (R-BTPs) were synthesized and characterized by NMR analysis and X-ray diffraction. These ruthenium (II) complexes were applied in the transfer hydrogenation of ketones. Their different catalytic activity were attributed to the alkyl arms on the 2,6-bis(5,6-dialkyl-1,2,4-triazin-3-yl)pyridine. As the length of the alkyl arms rising, the catalytic activities of the complex catalysts decreased. By means of 0.4 mol % catalyst RuCl2(PPh3)(3-methylbutyl-BTP) in refluxing 2-propanol, a variety of ketones were reduced to their corresponding alcohols with >95% conversion over a period of 3 h. (C) 2019 Elsevier Science. All rights reserved. (C) 2019 Elsevier Ltd. All rights reserved.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Wang, LD; Liu, TT or concate me.. Recommanded Product: 91-02-1

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article A Bifunctional Iron Nanocomposite Catalyst for Efficient Oxidation of Alkenes to Ketones and 1,2-Diketones WOS:000543700400014 published article about OXYGEN REDUCTION; ONE-POT; ASYMMETRIC EPOXIDATION; MOLECULAR-OXYGEN; ALLYLIC ALCOHOLS; NANOPARTICLES; PERFORMANCE; COMPLEXES; OLEFINS; ACIDS in [Xiao, Jianliang] Univ Liverpool, Dept Chem, Liverpool L69 7ZD, Merseyside, England; [Song, Tao; Ma, Zhiming; Ren, Peng; Yang, Yong] Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China; [Ma, Zhiming; Ren, Peng] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Yuan, Youzhu] Coll Chem & Chem Engn, Natl Engn Lab Green Chem Prod Alcohols Ethers Est, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China in 2020.0, Cited 74.0. Formula: C12H9NO. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

We herein report the fabrication of a bifunctional iron nanocomposite catalyst, in which two catalytically active sites of Fe-N-x and Fe phosphate, as oxidation and Lewis acid sites, were simultaneously integrated into a hierarchical N,P-dual doped porous carbon. As a bifunctional catalyst, it exhibited high efficiency for direct oxidative cleavage of alkenes into ketones or their oxidation into 1,2-diketones with a broad substrate scope and high functional group tolerance using TBHP as the oxidant in water under mild reaction conditions. Furthermore, it could be easily recovered for successive recycling without appreciable loss of activity. Mechanistic studies disclose that the direct oxidation of alkenes proceeds via the formation of an epoxide as intermediate followed by either acid-catalyzed Meinwald rearrangement to give ketones with one carbon shorter or nucleophilic ring-opening to generate 1,2-diketones in a cascade manner. This study not only opens up a fancy pathway in the rational design of Fe-N-C catalysts but also offers a simple and efficient method for accessing industrially important ketones and 1,2-diketones from alkenes in a cost-effective and environmentally benign fashion.

Formula: C12H9NO. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Song, T; Ma, ZM; Ren, P; Yuan, YZ; Xiao, JL; Yang, Y or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Safety of Phenyl(pyridin-2-yl)methanone. In 2020.0 ANAL CHEM published article about STRUCTURAL-ANALYSIS; STRESS; BONDS in [Waeldchen, Fabian; Heiles, Sven] Justus Liebig Univ Giessen, Inst Inorgan & Analyt Chem, Analyt Chem, D-35392 Giessen, Germany; [Mohr, Franziska; Wagner, Andreas H.] Heidelberg Univ, Dept Cardiovasc Physiol, D-69120 Heidelberg, Germany in 2020.0, Cited 50.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

Local lipid variations in tissues are readily revealed with mass spectrometry imaging (MSI) methods, and the resulting lipid distributions serve as bioanalytical signatures to reveal cell- or tissue-specific lipids. Comprehensive MSI lipid mapping requires measurements in both ion polarities. Additionally, structural lipid characterization is necessary to link the lipid structure to lipid function. Whereas some structural elements of lipids are readily derived from high-resolution mass spectrometry (MS) and tandem-MS (MSn), the localization of C=C double bonds (DBs) requires specialized fragmentation and/or functionalization methods. In this work, we identify a multifunctional matrix-assisted laser desorption/ionization (MALDI) matrix for spatially resolved lipidomics investigations that reacts with lipids in Paterno-Biichi (PB) reactions during laser irradiation facilitating DB-position assignment and allows dual-polarity high-resolution MALDI-MSI and MALDI (MSI)-I-2 studies. By screening 12 compounds for improved ionization efficiency in positive-/negative-ion mode and the functionalization yield compared to the previously introduced reactive MALDI matrix benzophenone, 2-benzoylpyridine (BzPy) is identified as the best candidate. The new matrix enables DB localization of authentic standards belonging to 12 lipid classes and helps to assign 133/58 lipid features in positive-/negative-ion mode from mouse cerebellum tissue. The analytical capabilities of BzPy as a multifunctional MALDI-MSI matrix are demonstrated by imaging endogenous and PB-functionalized lipids in mouse kidney sections with 7 mu m lateral resolution in both ion modes. Tracking diagnostic lipid DB-position fragment ions in mouse pancreatic tissue with down to 10 mu m pixel size allows us to identify the islets of Langerhans associated with lipid isomer upregulation and depletion.

Safety of Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Waldchen, F; Mohr, F; Wagner, AH; Heiles, S or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Cappello, D; Therien, DAB; Staroverov, VN; Lagugne-Labarthet, F; Gilroy, JB in [Cappello, Daniela; Therien, Denis A. B.; Staroverov, Viktor N.; Lagugne-Labarthet, Francois; Gilroy, Joe B.] Univ Western Ontario, Dept Chem, London, ON N6A 5B7, Canada; [Cappello, Daniela; Therien, Denis A. B.; Staroverov, Viktor N.; Lagugne-Labarthet, Francois; Gilroy, Joe B.] Univ Western Ontario, CAMBR, London, ON N6A 5B7, Canada published Optoelectronic, Aggregation, and Redox Properties of Double-Rotor Boron Difluoride Hydrazone Dyes in 2019.0, Cited 71.0. Quality Control of Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

We develop the chemistry of boron difluoride hydrazone dyes (BODIHYs) bearing two aryl substituents and explore their properties. The low-energy absorption bands (lambda(max)=427-464 nm) of these dyes depend on the nature of the N-aryl groups appended to the BODIHY framework. Electron-donating and extended pi-conjugated groups cause a redshift, whereas electron-withdrawing groups result in a blueshift. The title compounds were weakly photoluminescent in solution and strongly photoluminescent as thin films (lambda(PL)=525-578 nm) with quantum yields of up to 18 % and lifetimes of 1.1-1.7 ns, consistent with the dominant radiative decay through fluorescence. Addition of water to THF solutions of the BODIHYs studied causes molecular aggregation which restricts intramolecular motion and thereby enhances photoluminescence. The observed photoluminescence of BODIHY thin films is likely facilitated by a similar molecular packing effect. Finally, cyclic voltammetry studies confirmed that BODIHY derivatives bearing para-substituted N-aryl groups could be reversibly oxidized (E-ox1=0.62-1.02 V vs. Fc/Fc(+)) to their radical cation forms. Chemical oxidation studies confirmed that para-substituents at the N-aryl groups are required to circumvent radical decomposition pathways. Our findings provide new opportunities and guiding principles for the design of sought-after multifunctional boron difluoride complexes that are photoluminescent in the solid state.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Cappello, D; Therien, DAB; Staroverov, VN; Lagugne-Labarthet, F; Gilroy, JB or concate me.. Quality Control of Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Proximity Effect in Uranyl Coordination of the Cucurbit[6]uril-Bipyridinium Pseudorotaxane Ligand for Promoting Host-Guest Synergistic Chelating WOS:000675430900047 published article about METAL-ORGANIC FRAMEWORK; POLYROTAXANES; INCLUSION; DESIGN in [Li, Fei-Ze; Liu, Ning] Sichuan Univ, Inst Nucl Sci & Technol, Minist Educ, Key Lab Radiat Phys & Technol, Chengdu 610064, Peoples R China; [Li, Fei-Ze; Geng, Jun-Shan; Hu, Kong-Qiu; Yu, Ji-Pan; Chai, Zhi-Fang; Mei, Lei; Shi, Wei-Qun] Chinese Acad Sci, Inst High Energy Phys, Lab Nucl Energy Chem, Beijing 100049, Peoples R China; [Chai, Zhi-Fang] Chinese Acad Sci, Ningbo Inst Ind Technol, Engn Lab Adv Energy Mat, Ningbo 315201, Zhejiang, Peoples R China in 2021, Cited 43. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6. Safety of Ethyl nicotinate

behavior of cucurbituril-bipyridinium pseudorotaxane ligand by utilizing meta-functionalized bipyridinium dicarboxylate guest. A tailored pseudorotaxane precursor involving 1,1′-(hexane-1,6-diyl)bis(3-cyanopyridin-1-ium) bromide (C6BPCN3) and cucurbit[6]uril (CB[6]) has designed and synthesized. Through in situ hydrolysis of the pseudorotaxane ligands and their coordination assembly with uranyl cations, seven new uranyl-rotaxane coordination polymers URCP1-URCP7 have been obtained under hydrothermal conditions in the presence of different anions. It is demonstrated that the variation of carboxylate groups from para- to meta-position greatly affected the coordination behaviors of the metafunctionalized pseudorotaxane linkers, which are enriched from simple guest-only binding to host-guest simultaneous coordination and synergistic chelating. This effective regulation on uranyl coordination of supramolecular pseudorotaxane can be attributed to the proximity effect, which refers to the meta-position carboxyl group being spatially closer to the portal carbonyl group of CB[6]. Moreover, by combining other regulation methods such as introducing competing counterions and modulating solution acidity, the nuclearity of the uranyl center and the coordination patterns of the pseudorotaxane ligand can be diversely tuned, which subsequently exert great influence on the final dimensionality of resultant uranyl compounds. This work presents a large diversity of uranyl-based coordination polyrotaxane compounds with fascinating mechanically interlocked components and, most importantly, provides a feasible approach to adjust and control the metal coordination behavior of the pseudorotaxane ligand that might expand the scope of application of such supramolecular ligands.

Safety of Ethyl nicotinate. About Ethyl nicotinate, If you have any questions, you can contact Li, FZ; Geng, JS; Hu, KQ; Yu, JP; Liu, N; Chai, ZF; Mei, L; Shi, WQ or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem