Tag: M.W=150-200

Lazaro, F. published the artcileStopped-flow injection determination of copper(II) at the ng ml^-1 level, Application of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, the publication is Analytica Chimica Acta (1984), 177-85, database is CAplus.

A stopped-flow injection method for determination of Cu(II) in the range 0.2-300 ng/mL is proposed, based on the catalytic effect of this ion on the 2,2′-dipyridylketone hydrazone/H₂O₂ reaction. The oxidation product shows an intense blue fluorescence that is monitored at excitation wavelength = 350 nm, emission wavelength = 427 nm. The sampling rate (72/h), relative standard deviation (1.4%), and the lack of interference from most foreign ions allowed application of the method to the determination of Cu in foods and blood serum.

Analytica Chimica Acta published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Application of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lazaro Boza, Fernando published the artcileCatalytic-fluorometric determination of copper at the nanograms per milliliter level by flow injection analysis, COA of Formula: C11H10N4, the publication is Analyst (Cambridge, United Kingdom) (1984), 109(3), 333-7, database is CAplus.

A catalytic-fluorometric method for the determination of Cu(II) at the ng/mL level is proposed, based on the catalytic action of Cu(II) on the oxidation of 2,2′-bipyridyl ketone hydrazone (I) by dissolved O. To obtain the maximum anal. signal, 2 steps are necessary: oxidation of I (basic medium) and development of fluorescence (strongly acidic medium). Flow injection anal. is suitable for this determination as it is sensitive and rapid. The calibration graph shows 2 linear intervals, 8-30 ng/mL (relative standard deviation 2.3%) and 40-300 ng/mL (relative standard deviation 2.0%). The sampling frequency is 100 h^-1 for an injected volume of 60 μL.

Analyst (Cambridge, United Kingdom) published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, COA of Formula: C11H10N4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lazaro, Fernando published the artcileCatalytic-fluorometric determination of EDTA and iron(III) by flow injection analysis. Inhibition methods, Quality Control of 2215-33-0, the publication is Fresenius’ Zeitschrift fuer Analytische Chemie (1985), 321(5), 467-70, database is CAplus.

Methods are described for the direct determination of EDTA and indirect determination of Fe(III), based on the inhibition effect of EDTA on the catalytic action of Cu(II) on the oxidation of 2,2′-dipyridyl ketone hydrazone by H₂O₂ and on the decrease of this inhibition effect in the presence of Fe(III), resp. These methods allow the determination of EDTA in the ranges 0.4-2.0 and 0.2-1.0 μg.mL^-1 for the normal and reversed flow-injection anal. (FIA) modes, resp., and 40-240 ng.mL^-1 for Fe(III) by reversed FIA.

Fresenius’ Zeitschrift fuer Analytische Chemie published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Quality Control of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lazaro, Fernando published the artcileSimultaneous catalytic-fluorometric determination of copper and mercury by flow-injection analysis, Application In Synthesis of 2215-33-0, the publication is Fresenius’ Zeitschrift fuer Analytische Chemie (1985), 320(2), 128-32, database is CAplus.

A catalytic-fluorometric method for the simultaneous determination of Cu(II) and Hg(II) is based on their catalytic effects on the oxidation of dipyridyldiketone phenylhydrazone and 2,2′-dipyridylketone hydrazone, resp., using the flow-injection anal./stopped-flow mode. The errors in the determination of these cations are <10%, with a sampling rate of 45 samples per h and the relative standard deviation is 0.91% and 1.6% for Cu(II) and for Hg(II), resp.

Fresenius’ Zeitschrift fuer Analytische Chemie published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Application In Synthesis of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Culp, Jeffrey T. published the artcileScreening Hofmann Compounds as CO₂ Sorbents: Nontraditional Synthetic Route to Over 40 Different Pore-Functionalized and Flexible Pillared Cyanonickelates, SDS of cas: 1008506-24-8, the publication is Inorganic Chemistry (2013), 52(8), 4205-4216, database is CAplus and MEDLINE.

A simple reaction scheme based on the heterogeneous intercalation of pillaring ligands (HIPLs) provides a convenient method for systematically tuning pore size, pore functionality, and network flexibility in an extended series of pillared cyanonickelates (PICNICs), commonly named Hofmann compounds The versatility of the approach is demonstrated through the preparation of over 40 different PICNICs containing pillar ligands ranging from âˆ? to âˆ?5 Å in length and modified with a wide range of functional groups, including fluoro, aldehyde, alkylamine, alkyl, aryl, trifluoromethyl, ester, nitro, ether, and non-metalated 4,4′-bipyrimidine. The HIPL method involves reaction of a suspension of preformed polymeric sheets of powd. anhydrous Ni cyanide with an appropriate pillar ligand in refluxing organic solvent, converting the planar [Ni₂(CN)₄]_n networks into polycrystalline three-dimensional porous frameworks containing the organic pillar ligand. Preliminary studies indicate that the HIPL reaction is also amenable to forming Co(L)Ni(CN)₄, Fe(L)Ni(CN)₄, and Fe(L)Pd(CN)₄ networks. The materials show variable adsorption behavior for CO₂ depending on the pillar length and pillar functionalization. Several compounds show structurally flexible behavior during the adsorption and desorption of CO₂. The newly discovered flexible compounds include two flexible Fe(L)Ni(CN)₄ derivatives that are structurally related to previously reported porous spin-crossover compounds The preparations of 20 pillar ligands based on ring-functionalized 4,4′-dipyridyls, 1,4-bis(4-pyridyl)benzenes, and N-(4-pyridyl)isonicotinamides are also described.

Inorganic Chemistry published new progress about 1008506-24-8. 1008506-24-8 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester,Ether,Pyridine,Boronic Acids,Boronic acid and ester, name is 3-Methoxypyridine-4-boronic acid, and the molecular formula is C6H8BNO3, SDS of cas: 1008506-24-8.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Madura, J. D. published the artcilePhysical and structural properties of taurine and taurine analogs, Recommanded Product: Pyridine-3-sulfonic acid, the publication is Amino Acids (1997), 13(2), 131-139, database is CAplus.

The inhibition of the phosphorylation of an ∼20kDa protein present in the mitochondrial fraction of the rat retina by taurine and taurine analogs was investigated using computational methods. Correlations between mol. weight, mol. volume, and calculated pKa values vs. IC₅₀ values are reported. These data appear to support the hypotheses according to Lombardini and Props that the inhibition of the phosphorylation of an ∼20 kDa protein by taurine and taurine analogs dependent on (i) the critical distance between the N and S atoms in the taurine moiety (S-C-C-N) of the analog, (ii) the environment of the N atom in the taurine analog (saturated ring vs. unsaturated ring), and (iii) the placement of both the S and N atoms not being present simultaneously in the ring structure. Using computational methods results supporting hypotheses (i) and (ii) are presented.

Amino Acids published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Recommanded Product: Pyridine-3-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Motz, Rachel N. published the artcileHigh-Throughput Screening of Earth-Abundant Water Reduction Catalysts toward Photocatalytic Hydrogen Evolution, Computed Properties of 91-02-1, the publication is Inorganic Chemistry (2021), 60(2), 774-781, database is CAplus and MEDLINE.

Cobalt(II) glyoxime and heterocycle complexes [Co(LL)₂pyCl]ⁿ⁺ (LL – α-dioxime, 8-quinolinols, α-diketone dihydrazides, bipyridines, phenanthrolines, pyridyltetrazoles, etc.; n = 0-2) were generated in situ and screened for cocatalytic activity in Eosin Y-catalyzed photoreduction of water in the presence of triethylamine as sacrificial reductant. Noble-metal photosensitizers and water reduction co-catalysts (WRCs) still present the highest activity in homogeneous photocatalytic hydrogen production The search for earth-abundant alternatives is usually limited by the time required to screen new catalyst combinations; however, here, we utilize newly designed and developed high-throughput photoreactors for the parallel synthesis of novel WRCs and colorimetric screening of hydrogen evolution. This unique approach allowed rapid optimization of photocatalytic water reduction using the organic photosensitizer Eosin Y and the archetypal cobaloxime WRC [Co(GL1)₂pyCl], where GL1 is dimethylglyoxime and py is pyridine. Subsequent combinatorial synthesis generated 646 unique cobalt complexes of the type [Co(LL)₂pyCl], where LL is a bidentate ligand, that identified promising new WRC candidates for hydrogen production D. functional theory (DFT) calculations performed on such cobaloxime derivative complexes demonstrated that reactivity depends on hydride affinity. Alkyl-substituted glyoximes were necessary for hydrogen production and showed increased activity when paired with ligands containing strong hydrogen-bond donors. Using a newly developed method of H₂ detection using colorimetric tape, we screened a massive parallel library of cobaloxime water reduction catalysts. This noble-metal-free system of photocatalytic water reduction was optimized using Eosin Y as a photosensitizer. Screening identified a series of intriguing heteroleptic species with high activity, while DFT calculations of potential reaction intermediates correlated the activity of homoleptic cobaloximes to their hydride binding affinity.

Inorganic Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Computed Properties of 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Kramberger, L. published the artcileHeterocycles. CXXVII. Action of sulfur on some heterocyclic compounds. Formation of thioamides, oxidative cyclization and thiation, Quality Control of 2215-33-0, the publication is Journal of Heterocyclic Chemistry (1975), 12(2), 337-42, database is CAplus.

The formation of heterocyclic thioamides from alkylpyridines, heteroaromatic amines and sulfur was investigated. Oxidative cyclization of these thioamides afforded the corresponding thiazoloazines. Attempted thiation of some hydrazones gave triazolopyridines and some examples of direct thiation of heterocycles are given. Thus, 2-methylpyridine, 5, and RNH2 gave 10 I (R = 3-pyridyl, 4-pyridyl, 4-methyl-2-pyridyl, 5-methyl-2-pyridyl, 2-pyridazyl, 2-pyrazyl, 2-triazolyl, 5-tetrazolyl, 2-benzothiazolyl, anilino). Oxidative cyclization of I (R = 5-methyl-2-pyridyl) gave II. Attempted thiation of III gave IV and thiation of 2-(N-2-pyridylformimidoyl)pyridine gave I (R = 2-pyridyl).

Journal of Heterocyclic Chemistry published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Quality Control of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Li, Dan-Yang published the artcileElectronic Effect-Guided Rational Design of Candida antarctica Lipase B for Kinetic Resolution Towards Diarylmethanols, SDS of cas: 91-02-1, the publication is Advanced Synthesis & Catalysis (2021), 363(7), 1867-1872, database is CAplus.

Herein, we developed an electronic effect-guided rational design strategy to enhance the enantioselectivity of Candida antarctica lipase B (CALB) mutants towards bulky pyridyl(phenyl)methanols. Compared to W104A mutant previously reported with reversed S-stereoselectivity toward sec-alcs., three mutants (W104C, W104S and W104T) displayed significant improvement of S-enantioselectivity in the kinetic resolution (KR) of various Ph pyridyl Me acetates due to the increased electronic effects between pyridyl and polar residues. The electronic effects were also observed when mutating other residues surrounding the stereospecificity pocket of CALB, such as T42A, S47A, A281S or A281C, and can be used to manipulate the stereoselectivity. A series of bulky pyridyl(phenyl) methanols, including S-(4-chlorophenyl)(pyridin-2-yl) methanol (S-CPMA), the intermediate of bepotastine, were obtained in good yields and ee values.

Advanced Synthesis & Catalysis published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, SDS of cas: 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Scarry, Sarah M. published the artcileSynthesis of Kappa Opioid Antagonists Based On Pyrrolo[1,2-α]quinoxalinones Using an N-Arylation/Condensation/Oxidation Reaction Sequence, Application of 2-Bromopyridin-3-amine, the publication is Journal of Organic Chemistry (2016), 81(21), 10538-10550, database is CAplus and MEDLINE.

The quinoxaline and quinoxalinone family of N heterocycles is present in mols. of therapeutic relevance for diverse applications ranging from infectious diseases to neuroscience targets. Here, the authors describe a general synthetic sequence to afford pyrrolo[1,2-α]pyrazinones from com. available starting materials and their use in preparing potential kappa opioid receptor antagonists. The biol. data obtained from the latter set of compounds is briefly presented and discussed.

Journal of Organic Chemistry published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Application of 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem