Tag: M.W=150-200

Lee, Kum-Tatt published the artcileUse of pyridine-2-aldehyde-2′-pyridylhydrazone for trace analysis of copper in foods, HPLC of Formula: 2215-33-0, the publication is Mikrochimica Acta (1976), 2(5-6), 505-13, database is CAplus.

Aqueous extracts of food were treated with a solution of pyridine-2-aldehyde-2′-pyridylhydrazone [2215-33-0] in 0.01M HCl (100 mg/100 ml) under slightly alk. conditions and the complex between Cu and the reagent was extracted with amyl alc. and the Cu content determined by colorimetry or by at. absorption. In tests with 0-10 mg Cu/20 g sugar and 0-20 μg/0.2 g defatted cocoa, 98-102% of the Cu was recovered by this method.

Mikrochimica Acta published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, HPLC of Formula: 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Prakash, Sekar published the artcileRhenium(I)-Catalyzed ortho-C-H Addition to Bicyclic Alkenes, Category: pyridine-derivatives, the publication is Chemistry – An Asian Journal (2018), 13(13), 1664-1668, database is CAplus and MEDLINE.

Hydroarylation of bicyclic alkenes was developed using a low-valent Re^I-catalyzed, directing group-assisted C-H bond activation strategy. The addition of sodium acetate significantly improves the reaction efficiency; moreover, bicyclic alkenes such as 7-oxa and aza benzonorbornadienes worked efficiently under this reaction condition. Preliminary mechanistic studies suggest that, after the alkene insertion, the rhenacycle preferentially undergoes protonolysis rather than reductive elimination.

Chemistry – An Asian Journal published new progress about 85237-71-4. 85237-71-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is 5-Methyl-2-(p-tolyl)pyridine, and the molecular formula is C13H13N, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Schneider, Cedric published the artcileDirected ortho-Metalation-Cross-Coupling Strategies. One-Pot Suzuki Reaction to Biaryl and Heterobiaryl Sulfonamides, Application of Pyridine-3-sulfonic acid, the publication is Organic Letters (2011), 13(14), 3588-3591, database is CAplus and MEDLINE.

A general synthesis of stable ortho-boropinacolato aryl and heteroaryl sulfonamides by directed ortho-metalation (DoM) and either MeOBPin or i-PrOBpin electrophile quench is described. A one-pot metalation-Suzuki cross-coupling procedure for the synthesis of biaryls and heterobiaryls, and a complementary DoM-Ir-catalyzed boronation sequence are delineated.

Organic Letters published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Application of Pyridine-3-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Vallejo, Luis Felipe published the artcileRenaturation and purification of bone morphogenetic protein-2 produced as inclusion bodies in high-cell-density cultures of recombinant Escherichia coli, COA of Formula: C5H5NO3S, the publication is Journal of Biotechnology (2002), 94(2), 185-194, database is CAplus and MEDLINE.

Escherichia coli was genetically engineered to produce recombinant human bone morphogenetic protein-2 (rhBMP-2) in a non-active aggregated form using a temperature-inducible expression system. High concentrations of both biomass (75 g cell dry weight per L of culture broth) and inactive rhBMP-2 (8.6 g l^-1) were obtained by applying a high-cell-d. cultivation procedure. After washing and solubilizing the inclusion bodies, rhBMP-2 was refolded and dimerized at concentrations up to 100 mg l^-1 by means of a simple dilution method with yields exceeding 50%. Finally, a one-step purification procedure based on affinity chromatog. was implemented to isolate the rhBMP-2 dimer. With the established renaturation and purification protocols, yields of more than 10 mg rhBMP-2 dimer per g cell dry weight were obtained corresponding to 750 mg rhBMP-2 dimer per L of culture broth. The purified rhBMP-2 dimer showed biol. activity equivalent to CHO produced rhBMP-2 as tested by the induction of alk. phosphatase activity in C2C12 cells.

Journal of Biotechnology published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C4H3Cl2N3, COA of Formula: C5H5NO3S.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Ly, Hoang Nguyen published the artcileSpectroscopy, electrochemistry, and nucleophilicity of nickel and cobalt complexes of 2′-pyridine carboxaldehyde 2′-pyridylhydrazone (papyH), Recommanded Product: 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, the publication is Inorganica Chimica Acta (2011), 378(1), 115-120, database is CAplus.

Ni and Co complexes of pyridine-2-carboxaldehyde 2-pyridylhydrazone (papyH) and N-methyl(pyridine-2-carboxaldehyde 2-pyridylhydrazone) (papyMe) were fully characterized through electrochem., titration, and alkylation with Me iodide. The results were compared with existing data on similar Zn and Fe complexes. Both rate constants for alkylation and ligand pK_a depend on the coordinated metal and can be understood based on the influence of d electrons on the ligand MOs.

Inorganica Chimica Acta published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Recommanded Product: 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Karaman, Rafik published the artcileSynthesis and characterization of the first water-soluble closely interspaced cofacial porphyrin dimer, Synthetic Route of 636-73-7, the publication is Journal of Organic Chemistry (1991), 56(11), 3470-2, database is CAplus.

The only documented example of a quadruply-bridged, closely-interspaced cofacial porphyrin dimer was synthesized by Kagan (1977). The target of this communication is the synthesis and characterization of the first water soluble quadruply-bridged, closely-interspaced cofacial porphyrin I (R = R¹). Reaction of meso-tetrakis(3-bromomethylphenyl)porphyrin with m-pyridinesulfonamide provides the closely-interspaced cofacial porphyrin dimer I (R = R²) which on quaternization with MeI provides the water soluble I (R = R¹). Reactions of I with Zn(OAc)₂ provided the corresponding bis-zinc complexes I. Porphyrins I and their bis-zinc complexes, exist in a closed down conformation with closely approaching porphyrin planes or in an open conformation. It was established, on the basis of ¹H-NMR UV/vis, and emission spectrophotometries, and I (R = R²) exists in a closed down conformation in DMSO or acetone and a more open conformation is CHCl₃. With zinc complexes of I (or protonated I) the conformation is open regardless of the solvent.

Journal of Organic Chemistry published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Synthetic Route of 636-73-7.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Parry, Paul R. published the artcileNew shelf-stable halo- and alkoxy-substituted pyridylboronic acids and their Suzuki cross-coupling reactions to yield heteroarylpyridines, Safety of (6-Ethoxypyridin-3-yl)boronic acid, the publication is Synthesis (2003), 1035-1038, database is CAplus.

New shelf-stable pyridylboronic acids have been synthesized: bromine-lithium exchange followed by reaction with triisopropylborate yielded 2-fluoro-5-pyridylboronic acid, 3-bromo-5-pyridylboronic acid and 2-ethoxy-5-pyridylboronic acid; directed lithiation followed by reaction with trimethylborate or triisopropylborate afforded 2-methoxy-3-pyridylboronic acid, 3-bromo-6-methoxy-4-pyridylboronic acid and 3-bromo-6-ethoxy-4-pyridylboronic acid. Cross-coupling of pyridylboronic acids with 3-bromoquinoline [Cs₂CO₃, Pd(PPh₃)₂Cl₂, 1,4-dioxane, 95 °C] gave pyridinylquinoline derivatives in 50-77% yields. Cross-coupling of (3-bromo-5-ethoxy-4-pyridinyl)boronic acid with 2-bromo-5-nitrothiophene gave 3-bromo-4-(5-nitro-2-thienyl)-6-ethoxypyridine (18).

Synthesis published new progress about 612845-44-0. 612845-44-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester,Ether,Boronic Acids,Boronic acid and ester, name is (6-Ethoxypyridin-3-yl)boronic acid, and the molecular formula is C7H10BNO3, Safety of (6-Ethoxypyridin-3-yl)boronic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Billingsley, Kelvin published the artcileHighly Efficient Monophosphine-Based Catalyst for the Palladium-Catalyzed Suzuki-Miyaura Reaction of Heteroaryl Halides and Heteroaryl Boronic Acids and Esters, Product Details of C7H10BNO3, the publication is Journal of the American Chemical Society (2007), 129(11), 3358-3366, database is CAplus and MEDLINE.

A highly active and efficient catalyst system derived from a palladium precatalyst and monophosphine ligands I or II for the Suzuki-Miyaura cross-coupling reaction of heteroaryl boronic acids and esters has been developed. This method allows for the preparation of a wide variety of heterobiaryls in good to excellent yields and displays a high level of activity for the coupling of heteroaryl chlorides as well as hindered aryl and heteroaryl halides. Specific factors that govern the efficacy of the transformation for certain heterocyclic motifs were also investigated.

Journal of the American Chemical Society published new progress about 612845-44-0. 612845-44-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester,Ether,Boronic Acids,Boronic acid and ester, name is (6-Ethoxypyridin-3-yl)boronic acid, and the molecular formula is C7H10BNO3, Product Details of C7H10BNO3.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lamers, Philip published the artcileBenzo[c]isothiazole 2-Oxides: Three-Dimensional Heterocycles with Cross-Coupling and Functionalization Potential, Name: 2-Bromopyridin-3-amine, the publication is Advanced Synthesis & Catalysis (2016), 358(22), 3649-3653, database is CAplus.

A robust method for the synthesis of benzo[c]isothiazole 2-oxides has been developed providing a range of functionalized derivatives starting from anilines and DMSO. The reaction sequence can be performed on a gram scale and leads to products that can easily be modified by standard cross-coupling reactions.

Advanced Synthesis & Catalysis published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Name: 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Cappello, Daniela published the artcileDual Emission, Aggregation, and Redox Properties of Boron Difluoride Hydrazones Functionalized with Triphenylamines, HPLC of Formula: 91-02-1, the publication is ChemPhotoChem, database is CAplus.

π-Conjugated mol. materials often exhibit interesting photoluminescence, redox, and optoelectronic properties that grant them utility as light-harvesting materials in solar cells, as the emissive component of organic light-emitting diodes, and as fluorescence sensors. Preparing dye conjugates by appending multiple dyes together to generate π-conjugated mols. is a common strategy to enhance the properties of these materials as it often imparts traits that cannot be achieved by the building blocks independently. Herein, we report mol. materials that incorporate boron difluoride hydrazone (BODIHY) and triphenylamine (TPA) units that exhibit charge-transfer character, dual-emission, and aggregation-induced emission. The title compounds have low-energy absorption bands (λ_abs=455-493 nm) that are red-shifted relative to BODIHYs with smaller π-systems and exhibit dual-emission in the solution, solid, and aggregate states. TPA-BODIHY (donor-acceptor) conjugates show multiple reversible redox events and, in combination, the data presented herein indicate that there is electronic communication throughout the donor-acceptor and acceptor-donor-acceptor π-systems. These results are rationalized with the use of computational chem. and solid-state structural anal. This study provides new opportunities for the design of mol. materials that are comprised of redox-active photoluminescent dyes, including BODIHY, and their potential applications.

ChemPhotoChem published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, HPLC of Formula: 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem