Tag: M.W=150-200

Weglinski, Zbigniew; Talik, Tadeusz published the artcile< Carboxylation of 2-hydroxypicolines>, Safety of 6-Amino-3-nitro-2-picoline, the main research area is carboxylation hydroxypicoline; pyridinol methyl carboxylation; picoline hydroxy carboxylation; pyridinecarboxylic acid hydroxymethyl.

Treatment of a mixture of 2-hydroxy-3-methylpyridine (I) and anhydrous K2CO3 with 55 atm CO2 at 220° for 9 h gave 87% 2-hydroxy-3-methyl-5-pyridinecarboxylic acid (II). Carboxylation of the Na and K salts of I gave 49.5 and 53% II, resp. Similarly, 2-hydroxy-5-methyl-, 2-hydroxy-6-methyl-, and 2-hydroxy-4-methylpyridine gave 2-hydroxy-5-methyl-3-pyridinecarboxylic acid, 2-hydroxy-6-methyl-3-pyridinecarboxylic acid, and 2-hydroxy-4-methyl-5-pyridinecarboxylic acid, resp. The isomeric hydroxymethylpyridinecarboxylic acids were also prepared by hydrolysis of the corresponding isomeric chlorocyanopicolines. The latter were obtained from isomeric aminopicolines by successive nitration, hydroxylation, chlorination, reduction, and Sandmeyer cyanation.

Roczniki Chemii published new progress about Carboxylation. 22280-62-2 belongs to class pyridine-derivatives, and the molecular formula is C6H7N3O2, Safety of 6-Amino-3-nitro-2-picoline.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Amthor, Sebastian; Braun, Hanna; Groene, Julius; Nauroozi, Djawed; Jacob, Timo; Rau, Sven published the artcile< Tailored protective groups for surface immobilization of ruthenium dyes>, Application of C10H8N2, the main research area is phosphonatomethyl silylphosphonatomethyl bipyridine ruthenium complex preparation surface immobilization dye.

McKenna reaction conditions are applied to the [Ru(4,4′-(CH2PO3Et2)2)(bpy)](PF6)2 model chromophore in order to obtain [Ru(4,4′-(CH2PO3TMS2)2)(bpy)](Br2-x)(PF6)x (x = 0-2) (2) by replacing the alkyl moieties of the phosphonates with TMS groups (TMS = trimethylsilyl). The model complex is immobilized onto both NiO powder and NiO electrodes on FTO (fluorine doped tin oxide) using organic solvents. The stability of surface binding in aqueous media and the DSC performance of 2 are tested and compared to those of a conventional dye of structure [Ru(4,4′-(CH2PO3TBA2)2)(bpy)](PF6)2 (1) (TBA = tetra-Bu ammonium). This is the first example of a ruthenium based chromophore with a phosphonic acid silyl-ester being directly immobilized onto a NiO surface. In addition, complex 2 exhibits superior stability towards desorption in aqueous media and at the same time showing improved DSC performance and stability in acetonitrile and a slightly higher dye loading on the electrode surface compared to 1.

Dalton Transactions published new progress about Chromophores. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Application of C10H8N2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Puszko, Aniela published the artcile< UV spectra of 2-halo-4-aminopicolines>, Application In Synthesis of 79055-59-7, the main research area is UV spectra halo derivative aminopyridine.

The UV spectra of 2-halogen-4-aminopicolines were measured in various solvents and the influence of substituent and solvent on position band and intensity are discussed in details.

Prace Naukowe Akademii Ekonomicznej imienia Oskara Langego we Wroclawiu published new progress about Solvent effect. 79055-59-7 belongs to class pyridine-derivatives, and the molecular formula is C6H7BrN2, Application In Synthesis of 79055-59-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wan, Yupeng; Lyu, Heng; Du, Hengyi; Wang, Dunjia; Yin, Guodong published the artcile< Synthesis and photophysical properties of europium pentafluorinated β-diketonate complexes>, Product Details of C10H8N2, the main research area is preparation europium pentafluorinated beta diketonate dipyridine phenanthroline complex; photoluminescence europium pentafluorinated beta diketonate dipyridine phenanthroline complex; thermal decomposition europium pentafluorinated beta diketonate dipyridine phenanthroline complex.

Two pentafluorinated β-diketone ligands, 4,4,5,5,5-pentafluoro-1-(4-methoxyphenyl)pentane-1,3-dione (PFMP) and 4,4,5,5,5-pentafluoro-1-(4-dimethyl amino-phenyl)pentane-1,3-dione (PFAP), had been employed to synthesize six novel europium(III) complexes with ancillary ligands 2,2-dipyridine, 1,10-phenanthroline and 4,7-diphenyl-1,10-phenanthroline. The synthesized europium(III) complexes were characterized by FTIR, 1H NMR, UV-visible, luminescence spectroscopy, elemental anal. and TGA. The photoluminescence spectra of these complexes showed the typical europium(III) red emissions in solid state and chloroform solution, assigned to 5D0 → 7Fj (j = 0-4) transitions. The higher values of intensity parameter Ω2 indicated that the europium ion was in a highly polarizable ligand field in these complexes. Europium(III) complexes with the β-diketone PFMP exhibited much better photoluminescence properties than complexes with the β-diketone PFAP. Especially, the europium(III) complex of the β-diketone PFMP with the auxiliary ligand 2,2-dipyridine displayed the longest lifetime value, the highest quantum yield and good CIE color coordinates matching the pure red color (x = 0.67, y = 0.33) in these complexes. In addition, the proposed energy transfer mechanisms and the thermal stability of these complexes were also studied and analyzed.

Research on Chemical Intermediates published new progress about Emission spectra. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Product Details of C10H8N2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hara, Naofumi; Uemura, Nao; Nakao, Yoshiaki published the artcile< C2-Selective silylation of pyridines by a rhodium-aluminum complex>, Related Products of 581-47-5, the main research area is dehydrogenative silylation CH activation pyridine rhodium aluminum heterobimetallic catalyst; Lewis acid rhodium aluminum heterobimetallic complex dehydrogenative silylation catalyst; crystal mol structure rhodium aluminum heterobimetallic complex.

We have developed a C2-selective dehydrogenative mono-silylation of a variety of pyridines using a Rh-Al complex [(R2PCH2N-1,2-C6H4NMe-1,2-C6H4NCH2PR2)AlClRhCl(L)]n (R = Ph, iPr; n = 1, L = nbd; n = 2, L void). Both the site- and mono-selectivity are controlled via the pyridine coordination to the Lewis-acidic Al center prior to the activation of the pyridine C(2)-H bond at the proximal Rh center. A reaction mechanism is proposed based on several mechanistic studies, including the isolation of a (2-pyridyl)silylrhodium intermediate.

Chemical Communications (Cambridge, United Kingdom) published new progress about C-H bond activation. 581-47-5 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Related Products of 581-47-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Oftadeh, Mohsen; Barfarakh, Zahra; Ravari, Fatemeh published the artcile< Luminescent excited-state intramolecular proton-transfer dyes based on 4-functionalized 6,6′-dimethyl-3,3′-dihydroxy-2,2′-bipyridine (BP(OH)2-Rs); DFT simulation study>, Application of C10H8N2, the main research area is ESIPT process; Excited state; Functionalized bipyridine dyes; Luminescence; Simulation.

The 4-functionalized 6,6′-dimethyl-3,3′-dihydroxy-2,2′-bipyridine dyes (BP(OH)2-Rs) have exhibited dienol and diketo emissions. The optimum geometrical structures for ground, singlet and triplet excited states are computed by DFT/B3LYP/6-31++G that showed the planarity of BP(OH)2-Rs structure. The emission spectra of the mols. are determined in the gas-phase at singlet and triplet excited states using CIS/6-31++G. The theor. calculations are carried out for BP(OH)2-Rs to understand the impact of different substituents (R = -H (I), -Br (II), -TMS (III), -C2H (IV), -terpyridine (V) and -bodipy (diazaboraindacene) (VI)) on excited-state intramol. proton transfer (ESIPT) in singlet and triplet excited states. Based on the calculations, the concerted diproton transfer proceeds in the triplet excited state, in which nπ* state has a significant participation in ESIPT. The spectral variation at ESIPT emission of BP(OH)2-Rs is influenced by the electron-acceptor ability of the substituents. The compound V revealed a higher spectral intensity compared to the others. From the comparison with the exptl. data, the mol. V is almost planar agreed with the X-ray structure and trend variation of wavelengths. The mol. VI contains bodipy chromophore that excitation energy transfers completely from BP(OH)2 core to a bodipy substituent, leading to emission from the lowest-lying bodipy substituent, and consequently, ESIPT does not occur for this dye.

Journal of Molecular Graphics & Modelling published new progress about 366-18-7. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Application of C10H8N2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Buttelmann, Bernd; Alanine, Alexander; Bourson, Anne; Gill, Ramanjit; Heitz, Marie-Paule; Mutel, Vincent; Pinard, Emmanuel; Trube, Gerhard; Wyler, Rene published the artcile< 2-(3,4-Dihydro-1H-isoquinolin-2yl)-pyridines as a novel class of NR1/2B subtype selective NMDA receptor antagonists>, Related Products of 79055-59-7, the main research area is NMDA receptor antagonist structure activity relationship design.

Recently, we disclosed 4-aminoquinolines as structurally novel NR1/2B subtype selective NMDA receptor antagonists. We would now like to report our findings on structurally related pyridine analogs. The SAR developed in this series resulted in the discovery of high affinity antagonists which are selective (vs α1 and M1 receptors) and active in vivo.

Bioorganic & Medicinal Chemistry Letters published new progress about Drug design. 79055-59-7 belongs to class pyridine-derivatives, and the molecular formula is C6H7BrN2, Related Products of 79055-59-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Palasek, B.; Puszko, A.; Biedrzycka, Z.; Sicinska, W.; Witanowski, M. published the artcile< Nitrogen NMR shieldings of 2-amino-5-nitro-6-methylpyridines>, Application In Synthesis of 22280-62-2, the main research area is aminonitromethylpyridine NMR shielding.

Nitrogen NMR shieldings (chem. shifts) of 2-amino-5-nitro-6-methylpyridine derivatives are assessed from the point of view of substituent-induced effects under conditions where alkyl, aryl, nitro, and nitroso moieties are substituents at the amino nitrogen. The nitro nitrogen shielding reveals only little variation upon varying the substituents, and this seems to indicate that steric hindrance which is likely to force the nitro group out of the plane of the aromatic ring reduces the π-electron conjugation with the latter, and with the amino group as well. On the other side, the pyridine nitrogen shielding shows large effects of substituents at the amino moiety, which suggests a significant conjugation between the ring and the amino group. The latter effects produce a remarkable deshielding of the pyridine nitrogen in the case of nitro and nitroso substituents at the amino group.

Spectroscopy (Amsterdam) published new progress about NMR (nuclear magnetic resonance). 22280-62-2 belongs to class pyridine-derivatives, and the molecular formula is C6H7N3O2, Application In Synthesis of 22280-62-2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xie, Feng; Li, Yibiao; Chen, Xiuwen; Chen, Lu; Zhu, Zhongzhi; Li, Bin; Huang, Yubing; Zhang, Kun; Zhang, Min published the artcile< Direct synthesis of novel quinoxaline derivatives via palladium-catalyzed reductive annulation of catechols and nitroarylamines>, Product Details of C6H7N3O2, the main research area is catechol nitroarylamine reusable palladium catalyst reductive cyclization; phenazine preparation.

A palladium-catalyzed new hydrogenative annulation reaction of catechols and nitroarylamines, allowing straightforward access to two classes of novel quinoxaline derivatives, was reported. The reaction proceeded with operational simplicity, an easily available catalyst system, a broad substrate scope and without the need for pre-functionalization, which offers the potential for further design of new reductive transformations of renewable resources into value-added products.

Chemical Communications (Cambridge, United Kingdom) published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent). 21901-29-1 belongs to class pyridine-derivatives, and the molecular formula is C6H7N3O2, Product Details of C6H7N3O2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Anisimov, Anton A.; Vysochinskaya, Yulia S.; Kononevich, Yuriy N.; Dolgushin, Fedor M.; Muzafarov, Aziz M.; Shchegolikhina, Olga I. published the artcile< Polyhedral phenylnickelsodiumsiloxanolate transformation in the presence of aromatic nitrogen-containing ligands>, Recommanded Product: 2,2′-Bipyridine, the main research area is nickel sodium polyhedral phenyl siloxanolate complex preparation crystal structure.

Two new polyhedral phenylmetallasiloxane complexes, {[PhSi(O)O-]6(Ni2+)6(Na+)2(μ3-OH)2[PhSi(O)O-]6}•2(BIPY)•4(DMF) (1) and {[PhSi(O)O-]6(Ni2+)3(Na+)6(μ5-OH)2[PhSi(O)O-]5}•7(PY)•2(BuOH)•2(H2O) (2) formed in the process of recrystallization of polyhedral phenylnickelsodiumsiloxane (Na+)2{[PhSi(O)O-]6(Ni2+)4(Na+)4(μ3-OH)2[PhSi(O)O-]6}•16(BuOH) (A) from DMF in the presence of 2,2-bipyridine (complex 1) or from pyridine (complex 2) are described. σ-Donor ligands of the pyridine series (pyridine and 2,2-bipyridine) play a crucial role in the process of dissociation of the initial metallasiloxane framework and its reassembly on a new matrix of metal ions. Not only the metal-containing cationic layer is reconstructed with a change in the number, ratio, and spatial arrangement of nickel and sodium cations, but also changes the size of cyclic siloxane ligands.

Inorganica Chimica Acta published new progress about Crystal structure. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Recommanded Product: 2,2′-Bipyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem