Tag: M.W=200-250

Kerric, Gaelle published the artcileUse of polymer-supported phenyltin for the creation of aryl-aryl or aryl-heteroaryl bonds via Stille cross-coupling reactions, Synthetic Route of 89076-64-2, the publication is Journal of Organometallic Chemistry (2009), 695(1), 103-110, database is CAplus.

An insoluble polymer-supported phenyltin reagent was successfully used in Stille cross-coupling reactions with aryl- and heteroaryl halides. Cross-coupling products were isolated in good to high yields with very low contamination by tin and palladium residues after removal of the residual supported organotin halide. The regeneration and recyclability of the supported phenyltin reagent were also examined and proved to be possible, but required palladium cleaning of the grafted polymer to be efficient along 4 cycles when Pd(PPh₃)₄ was used as catalyst.

Journal of Organometallic Chemistry published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Synthetic Route of 89076-64-2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Bockman, T. M. published the artcileTime-resolved spectroscopy and charge-transfer photochemistry of aromatic EDA complexes with X-pyridinium cations, COA of Formula: C6H5F4NO3S, the publication is Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) (1992), 1581-94, database is CAplus.

Direct photoexcitation of 1:1 aromatic EDA complexes with various N-substituted X-pyridinium cations (X = nitro, fluoro, methoxy and acetoxy) is achieved by the specific irradiation of their charge-transfer (CT) absorption bands. Time-resolved picosecond spectroscopy refers to charge-transfer activation by the identification of the aromatic cation radical as the initial transient (T₁) formed in a photoinduced electron-transfer together with the X-pyridinyl radical. The homolytic fragmentation of the latter varies with the X-substituent in the order X = NO₂ > F > AcO > CH₃O, and the addition of X^{â€?/sup> to the aromatic donors leads to a series of cyclohexadienyl adducts that are identified as longer-lived transients (T₂) by time-resolved (nanosecond/μs) spectroscopy. The phototransients T₁ and T₂ together account for the different types of aromatic product (resulting from ring substitution, side-chain substitution and dimerization) that are generated by steady-state CT photochem. of the aromatic EDA complexes with X-pyridinium cations.}

Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C6H5F4NO3S, COA of Formula: C6H5F4NO3S.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Matsuo, Yutaka published the artcileSynthesis of Metal Fullerene Complexes by the Use of Fullerene Halides, Recommanded Product: 1-Fluoropyridiniumtriflate, the publication is Organometallics (2008), 27(14), 3403-3409, database is CAplus.

K(C₆₀R₅) (1, R = Me, Ph) was generated by deprotonation of C₆₀R₅H (2) and allowed to react with N-fluoropyridinium triflate and N-chloro- and N-bromosuccinimide in benzene at 25° for 10 min to obtain halogenated fullerenes C₆₀R₅X (3a: R = Me, X = F; 3b: R = Me, X = Cl; 3c: R = Me, X = Br; 4a: R = Ph, X = F; 4b: R = Ph, X = Cl, 4c: R = Ph, X = Br) in good yield. The pentamethyl[60]fullerene halides are useful for the synthesis of a variety of η⁵-fullerene metal complexes. The reaction of the fullerene bromide 3c with the low-valent transition metal complexes Na[Re(CO)₄], Fe(CO)₅, Ru₃(CO)₁₂, and Na[Co(CO)₄] gave Re(η⁵-C₆₀Me₅)(CO)₃ (5), Fe(η⁵-C₆₀Me₅)Br(CO)₂ (6), Ru(η⁵-C₆₀Me₅)Br(CO)₂ (7), and Co(η⁵-C₆₀Me₅)(CO)₂ (8), resp. The structures of halide 3c and rhenium complex 5 were determined by x-ray crystallog. Electrochem. measurements on 3b and 3c were also performed. The iron complex 6 was converted into Fe(η⁵-C₆₀Me₅)Cp (9), Fe(η⁵-C₆₀Me₅)Me(CO)₂ (10), Fe(η⁵-C₆₀Me₅)(CO)₂(CCH) (11), and Fe(η⁵-C₆₀Me₅)(CO)₂(CCPh) (12), by ligand exchange reactions.

Organometallics published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C6H5F4NO3S, Recommanded Product: 1-Fluoropyridiniumtriflate.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Ito, Satoshi published the artcileElectrochemical fluorination of (arylthio)methyl carboxylates and γ-phenylthio-γ-butyrolactone derivative, Computed Properties of 107263-95-6, the publication is Journal of the Electrochemical Society (2021), 168(6), 065502, database is CAplus.

Electrochem. fluorination of various (arylthio)methyl carboxylates was carried out in aprotic organic solvents containing poly(HF) salts to provide the corresponding O-fluoromethyl carboxylates in good to moderate yield. Electrochem. fluorination of a cyclic analog, a γ-phenylthio-γ-butyrolactone derivative was also achieved under ultrasonication to give the corresponding 4-fluorinated product in moderate yield.

Journal of the Electrochemical Society published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C6H5F4NO3S, Computed Properties of 107263-95-6.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Umemoto, Teruo published the artcileN-Fluoropyridinium triflate and its derivatives: useful fluorinating agents, Computed Properties of 107263-95-6, the publication is Tetrahedron Letters (1986), 27(37), 4465-8, database is CAplus.

N-Fluoropyridinum triflate and its derivatives, stable and nonhygroscopic crystals, were found to be widely applicable reagents for mild and selective fluorination of a variety of organic compounds, including aromatics, enol ethers or acetates, active methylene compounds, and organometallics.

Tetrahedron Letters published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C6H3ClFNO2, Computed Properties of 107263-95-6.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Tius, Marcus A. published the artcileSelectivity in aromatic fluorination. Introduction of fluorine probes into nabilone, Computed Properties of 107263-95-6, the publication is Chemical Communications (Cambridge) (1996), 2085-2086, database is CAplus.

Selective fluorination of the aromatic ring of nabilone leads to functional analogs with diminished affinity for the CB1 receptor, thereby confirming the hypothesis that the phenolic hydroxy group is engaged in a hydrogen bonding interaction with the receptor.

Chemical Communications (Cambridge) published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C10H11N3O3S, Computed Properties of 107263-95-6.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Sano, Tomoharu published the artcileSynthesis of N-(1-Nitropyren-6-yl and 8-yl)-2′-deoxyribonucleosides, HPLC of Formula: 107263-95-6, the publication is Chemical Research in Toxicology (1995), 8(5), 699-702, database is CAplus and MEDLINE.

A new type of 1-nitropyrene-DNA adduct via addition-elimination reaction was synthesized. Treatment of fluorinated 1-nitropyrene with 3′- and 5′-O-protected 2′-deoxyribonucleoside in DMSO at 140 °C afforded N-(1-nitropyren-6-yl or 8-yl)-2′-deoxyribonucleoside, I (R = H, R¹ = NO₂; R =NO₂, R¹ = H). These DNA adducts resulted from addition of the exocyclic amino group of deoxynucleosides to the fluorinated carbon of the fluoro-1-nitropyrene following elimination of fluoride anion. This is the first report that describes the 1-nitropyrene-DNA adducts in which aromatic ring moiety of 1-nitropyrene is covalently linked to the exocyclic amino group of the deoxyribonucleoside. From our findings, we suggest that the addition-elimination reaction may be responsible for the formation mechanism of the putative 1-nitropyrene-DNA adducts in vivo.

Chemical Research in Toxicology published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C6H5F4NO3S, HPLC of Formula: 107263-95-6.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Zafar, Sana published the artcileLinear and non linear optical properties of electron donor and acceptor pyridine moiety: a study by ab initio and DFT methods, COA of Formula: C11H8N2O2, the publication is Canadian Journal of Pure & Applied Sciences (2012), 6(1), 1827-1835, database is CAplus.

The Donor-Acceptor type conjugated mol. structures containing pyridine as a bridge were explored for non linear optical properties. The ab-initio Hartree Fock calculations and D. Functional Theory with B3LYP method were carried out employing 6-31 G basis set. The dipole moments (μ), polarizability (α), 1st hyperpolarizability (β), and HOMO-LUMO energy gap are calculated using the same level of theory. The dependence of the hyperpolarizability of different mol. structure on the nature of donor and acceptor on the pyridine is discussed from MO picture. Of all the mol. systems studied, the mol. system containing nitro as an acceptor and dimethylaniline as a donor has largest value of hyperpolarizability; 49.92 × 10^-30 esu and 164.61 × 10^-30 esu with ab-initio/HF and DFT/B3LYP, resp. The large value of β for the Donor-Acceptor pyridine derivative suggests the potential applications of these mol. systems in the development of non linear materials.

Canadian Journal of Pure & Applied Sciences published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C9H6BrNO, COA of Formula: C11H8N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Saha, Debasmita published the artcileIntramolecular cyclization of imidazo[1,2-a]pyridines via a silver mediated/palladium catalyzed C-H activation strategy, HPLC of Formula: 1174626-28-8, the publication is Organic Chemistry Frontiers (2019), 6(13), 2234-2239, database is CAplus.

A C-H activation reaction was developed using imidazo[1,2-a]pyridine adducts via an AgOAc-mediated, Pd catalyzed intramol. cyclization for the preparation of tetrazolylpyridoimidazo[4,5-c]quinoline derivatives I (R¹ = H, 9-Me, 9-Br, etc.; R² = t-Bu, Bn, cyclohexyl, etc.). The reaction was optimized and extensively explored using the Ugi/azide MCR as a tool to rapidly broaden substrate scope. Title compounds were screened against a cancer cell panel, and I (R¹ = H; R² = 1-phenylethyl) exhibited selective, antiproliferative activity against the MCF-7 (breast cancer) cell line. This C-H activation methodol. can be utilized to rapidly reach new chem.-space for drug discovery.

Organic Chemistry Frontiers published new progress about 1174626-28-8. 1174626-28-8 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine,Benzene,Ether, name is 2-Amino-6-benzyloxypyridine, and the molecular formula is C12H12N2O, HPLC of Formula: 1174626-28-8.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Sato, Masayuki published the artcileSynthesis of 5-fluoro-1,3-dioxin-4-ones: versatile building blocks of fluorinated compounds, Name: 1-Fluoropyridiniumtriflate, the publication is Journal of the Chemical Society, Chemical Communications (1991), 699-700, database is CAplus.

Fluorination of 5,6-unsubstituted dioxinone I (R = H) with F₂ followed by treatment with Et₃N affords the title compound I (R = F) which can be converted into fluorinated derivatives of formylacetic acid, e.g., (E)-AcOCH:CFCO₂Me or of heterocyclic systems, e.g., II and III.

Journal of the Chemical Society, Chemical Communications published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C6H5F4NO3S, Name: 1-Fluoropyridiniumtriflate.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem