Tag: M.W=200-250

An article Diverse reactivity to hypochlorite and copper ions based on a novel Schiff base derived from vitamin B6 cofactor WOS:000583948500064 published article about FLUORESCENT-PROBE; MITOCHONDRIA; BIOMARKER; SENSORS in [Li, Xiangqian; Wen, Qin; Gu, Jiapei; Wang, Qianming; Zheng, Yuhui] South China Normal Univ, Sch Chem, Guangzhou 510006, Peoples R China; [Liu, Wanqiang] Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China; [Wang, Qianming; Zhou, Guofu; Gao, Jinwei] South China Normal Univ, South China Acad Adv Optoelect, Inst Adv Mat, Guangzhou 510006, Peoples R China; [Wang, Qianming; Zhou, Guofu; Gao, Jinwei] South China Normal Univ, Guangdong Prov Key Lab Opt Informat Mat & Technol, Guangzhou 510006, Peoples R China in 2020.0, Cited 50.0. Category: pyridine-derivatives. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5

A new Schiff base receptor (2-amino-3-(((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene) amino)maleonitrile (GAL)) has been synthesized and such diaminomaleonitrile-based molecular framework is observed to be water soluble. GAL possesses both colorimetric and off-on fluorescent response in the presence of ClO-. The response time has been controlled within 6 min. The limit of detection (LOD) has been calculated to be 47.5 nM. The addition of Cu2+ can only induce clear color evolution from pale to deep yellow (LOD: 0.22 mu M) and no fluorescence changes are found. Moreover, its reliability and practicality are verified via the determination of ClO- in spiked samples of tap water and pond water. The exploration of bioactive vitamin B6 cofactor as a sensing platform will open a new way for multiple target recognition in competitive mediums. (C) 2020 Elsevier B.V. All rights reserved.

Category: pyridine-derivatives. Welcome to talk about 65-22-5, If you have any questions, you can contact Li, XQ; Wen, Q; Gu, JP; Liu, WQ; Wang, QM; Zhou, GF; Gao, JW; Zheng, YH or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Quality Control of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Recently I am researching about X-RAY-STRUCTURE; METAL-COMPLEXES; BIOLOGICAL EVALUATION; CRYSTAL-STRUCTURE; DNA-BINDING; METHYLDITHIOCARBAZATE SMDTC; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; CIRCULAR-DICHROISM; ZN(II) COMPLEXES, Saw an article supported by the Fundacao para a Ciencia e Tecnologia (FCT)Portuguese Foundation for Science and TechnologyEuropean Commission [UIDB/00100/2020, UIDP/00100/2020, PTDC/QUI-QAN/32242/2017, UID/Multi/00709/2019, UIDB/50006/2020, UIDB/04378/2020, SAICTPAC/0019/2015, PD/BD/128320/2017]; Programa Operacional Regional de Lisboa [LISBOA-01-0145-FEDER-007317]; FEDER fundsEuropean Commission [POCI-01-0145-FEDER-007491]. Published in ELSEVIER SCIENCE INC in NEW YORK ,Authors: Ramilo-Gomes, F; Addis, Y; Tekamo, I; Cavaco, I; Campos, DL; Pavan, FR; Gomes, CSB; Brito, V; Santos, AO; Domingues, F; Luis, A; Marques, MM; Pessoa, JC; Ferreira, S; Silvestre, S; Correia, I. The CAS is 65-22-5. Through research, I have a further understanding and discovery of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Schiff bases (SB) obtained from S-methyl dithiocarbazate and aromatic aldehydes: salicylaldehyde (H2L1), ovanillin (H2L2), pyridoxal (H2L3) and 2,6-diformyl-4-methylphenol (H3L4), and their corresponding Zn(II)complexes (1-4), are synthesized. All compounds are characterized by elemental analyses, infrared, UV-Vis, nuclear magnetic resonance spectroscopy and mass spectrometry. The structures of H2L2 and [Zn-2(L-1)(2)(H2O) (DMF)] (1a) (DMF = dimethylformamide) are solved by single crystal X-ray diffraction. The SB coordinates the metal center through the Ophenolate, Nimine and Sthiolate atoms. The radical scavenging activity is tested using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, with all ligand precursors showing IC50 values similar to 40 mu M. Cytotoxicity studies with several tumor cell lines (PC-3, MCF-7 and Caco-2) as well as a non-tumoral cell line (NHDF) are reported. Interestingly, 1 has relevant and selective antiproliferative effect against Caco-2 cells (IC50 = 9.1 mu M). Their antimicrobial activity is evaluated in five bacterial strains (Klebsiella pneumoniae, Acinetobacter baumannii, Listeria monocytogenes, Pseudomonas aeruginosa and Staphylococcus aureus) and two yeast strains (Candida albicans and Candida tropicalis) with some compounds showing bacteriostatic and fungicidal activity. The minimal inhibitory concentration (MIC90) of HnL against Mycobacterium tuberculosis is also reported, with H2L2 and H3L4 showing very high activity (MIC90 < 0.6 mu g/mL). The ability of the compounds to bind bovine serum albumin (BSA) and DNA is evaluated for H3L4 and [Zn-2(L-4)(CH3COO)] (4), both showing high binding constants to BSA (ca. 106 M 1) and ability to bind DNA. Overall, the reported compounds show relevant antitumor and antimicrobial properties, our data indicating they may be promising compounds in several fields of medicinal chemistry. Welcome to talk about 65-22-5, If you have any questions, you can contact Ramilo-Gomes, F; Addis, Y; Tekamo, I; Cavaco, I; Campos, DL; Pavan, FR; Gomes, CSB; Brito, V; Santos, AO; Domingues, F; Luis, A; Marques, MM; Pessoa, JC; Ferreira, S; Silvestre, S; Correia, I or send Email.. Quality Control of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

In 2020.0 MOLECULES published article about CHRONIC DISEASE PREVENTION; EXTENDED-RELEASE NIACIN; LIQUID-CHROMATOGRAPHY; B-6 VITAMERS; FOLIC-ACID; HUMAN-MILK; VITAMIN-B-6; SUPPLEMENTATION; FOLATE; INFLAMMATION in [Ibrahim, Ghada Rashad; Shah, Iltaf] UAE Univ, Coll Sci, Dept Chem, POB 15551, Al Ain, U Arab Emirates; [Gariballa, Salah; Yasin, Javed] UAE Univ, Coll Med, Dept Internal Med, POB 15551, Al Ain, U Arab Emirates; [Barker, James] Kingston Univ, Dept Chem & Pharmaceut Sci, Penrhyn Rd, Kingston Upon Thames KT1 2EE, Surrey, England; [Ashraf, Syed Salman] Khalifa Univ, Coll Arts & Sci, Dept Chem, POB 127788, Abu Dhabi, U Arab Emirates in 2020.0, Cited 48.0. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5. SDS of cas: 65-22-5

Water-soluble vitamins like B3 (nicotinamide), B6 (pyridoxine), and B9 (folic acid) are of utmost importance in human health and disease, as they are involved in numerous critical metabolic reactions. Not surprisingly, deficiencies of these vitamins have been linked to various disease states. Unfortunately, not much is known about the physiological levels of B6 vitamers and vitamin B3 in an ethnically isolated group (such as an Emirati population), as well as their relationship with obesity. The aim of the present study was to quantify various B6 vitamers, as well as B3, in the plasma of obese and healthy Emirati populations and to examine their correlation with obesity. A sensitive and robust HPLC-MS/MS-based method was developed for the simultaneous quantitation of five physiologically relevant forms of vitamin B6, namely pyridoxal, pyridoxine, pyridoxamine, pyridoxamine phosphate, and pyridoxal phosphate, as well as nicotinamide, in human plasma. This method was used to quantify the concentrations of these vitamers in the plasma of 57 healthy and 57 obese Emirati volunteers. Our analysis showed that the plasma concentrations of nicotinamide, pyridoxal, and pyridoxamine phosphate in the obese Emirati population were significantly higher than those in healthy volunteers (p< 0.0001,p= 0.0006, andp= 0.002, respectively). No significant differences were observed for the plasma concentrations of pyridoxine and pyridoxal phosphate. Furthermore, the concentrations of some of these vitamers in healthy Emirati volunteers were significantly different than those published in the literature for Western populations, such as American and European volunteers. This initial study underscores the need to quantify micronutrients in distinct ethnic groups, as well as people suffering from chronic metabolic disorders. SDS of cas: 65-22-5. About 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride, If you have any questions, you can contact Ibrahim, GR; Shah, I; Gariballa, S; Yasin, J; Barker, J; Ashraf, SS or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Formula: C8H10ClNO3. Chakraborty, M; Mondal, A; Chattopadhyay, SK in [Chakraborty, Moumita; Mondal, Antu; Chattopadhyay, Shyamal Kumar] Indian Inst Engn Sci & Technol, Dept Chem, Sibpur 711103, Howrah, India published Structural divergence in binuclear Cu(ii) pyridoxal Schiff base complexes probed by co-ligands: catecholase mimetic activity and sulphide ion sensing in 2020.0, Cited 74.0. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5.

Three hydroxymethyl bridged Cu(ii) complexes of a pyridoxal Schiff base ligand 4-((E)-(2-(pyridin-2-yl)ethylimino)methyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol (LH) have been synthesized and characterized on the basis of spectroscopic, elctrochemical and structural properties. The X-ray crystal structures of the complexes reveal dual denticity of the ligand, bidenticity in the absence of a co-ligand as in complex1, and tridenticity in the presence of a co-ligand such as SCN-/N(CN)(2)(-)as in complexes2and3. The complexes, though binuclear in the solid state, exist as a monomeric unit in solution due to the exceptionally long axial Cu-O-hydroxymethyl(2.4-2.5 angstrom) bond. All three complexes show efficient catalytic activities towards the aerial oxidation of 3,5-ditertiarybutylcatechol (DTBCH2) withk(cat)values of 5.38 x 10(4)h(-1), 1.18 x 10(5)h(-1)and 1.06 x 10(5)h(-1)in methanol. Complexes1and2also act as a selective sulphide ion sensor withK(b)values of 6.6 x 10(3)M(-1)and 8.1 x 10(3)M(-1), respectively, while their respective L.O.D. values are 3.4 mu M and 3.2 mu M.

Formula: C8H10ClNO3. About 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride, If you have any questions, you can contact Chakraborty, M; Mondal, A; Chattopadhyay, SK or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Synthesis and Evaluation of Pyridoxal Hydrazone and Acylhydrazone Compounds as Potential Angiogenesis Inhibitors WOS:000507320500005 published article about ISONICOTINOYL HYDRAZONE; IRON CHELATORS; IN-VITRO; VITAMIN-B-6; EXPRESSION; APOPTOSIS; ANALOGS; TARGETS; GROWTH; AGENTS in [Chen, Xuyang; Li, Hui; Luo, Hongjun; Lin, Zhexuan; Luo, Wenhong] Shantou Univ, Coll Med, Bioanalyt Lab, Xinling Rd 22, Shantou, Guangdong, Peoples R China in 2019.0, Cited 45.0. Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5

Background/Aims: Hydrazone and acylhydrazone derivatives, which are produced from aldehyde reacting with hydrazine or acylhydrazine, have been reported to exhibit antitumor activities. However, the angionenic effects of this kind of derivatives haven’t been elucidated. Here, we synthesized 12 pyridoxal hydrazone and acylhydrazone compounds and investigated their antiangiogenic effects and the underlying mechanisms. Method: 3-(4,5-Dimethylthiazol-2-yl)-2, 5-dipheyltetrazolium bromide assay was used to screen the inhibitory effects of the synthesized compounds on endothelial cells (ECs) proliferation. The compound with best inhibitory effect was further evaluated with wound-healing assay and tube formation assay. Calcein-Am assay was carried out to determine the content of intracellular labile iron pool (LIP). Intracellular reduced glutathione (GSH) was determined by spectrophotometry. Flow cytometry was used to determine cell cycle and apoptosis. Results: Compound 10 (3-hydroxy-5-[hydroxymethyl]-2-methyl-pyridine-4-carbaldehyde-2-naphthalen-1-acetyl hydrazone) showed the best inhibitory effect on human umbilical vascular ECs proliferation, with IC50 value of 25.4 mu mol/L. It not only inhibited wound-healing and tube formation of ECs, but also decreased the content of intracellular LIP and GSH. Furthermore, it arrested ECs cycle at S phase and induced cell apoptosis. Conclusions: Compound 10 exhibits antiangiogenic effects by reducing the content of intracellular LIP and GSH, and subsequently arresting cell cycle and inducing cell apoptosis.

Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Bye, fridends, I hope you can learn more about C8H10ClNO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article A new zinc(II) complex with N2O2-tetradentate schiff-base derived from pyridoxal-S-methylthiosemicarbazone: Synthesis, characterization, crystal structure, DFT, molecular docking and antioxidant activity studies WOS:000645617700015 published article about TRANSITION-METAL-COMPLEXES; EFFECTIVE CORE POTENTIALS; GROWTH-FACTOR RECEPTOR; THIOSEMICARBAZONE DERIVATIVES; BIOLOGICAL-ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; COPPER(II) COMPLEXES; LIGANDS; NICKEL(II); ANTITUMOR in [Poladian, Qumars; Ilhan-Ceylan, Berat; Kurt, Yasemin] Istanbul Univ Cerrahpasa, Engn Fac, Dept Chem, TR-34320 Istanbul, Turkey; [Sahin, Onur] Sinop Univ, Fac Hlth Sci, Dept Occupat Hlth & Safety, TR-57000 Sinop, Turkey; [Karakurt, Tuncay] Kirsehir Ahi Evran Univ, Fac Engn Architecture, Dept Chem & Proc Engn, TR-40100 Kirsehir, Turkey in 2021.0, Cited 69.0. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5. Product Details of 65-22-5

A new unsymmetrical N2O2-tetradentate Schiff-base complex of zinc(II) was synthesized by the template reaction of pyridoxal-S-methylthiosemicarbazone and 2-hydroxy-4-methoxy-benzaldehyde as starting compounds. S-methylthiosemicarbazone (1) and zinc(II) complex [Zn(L)CH3OH] ( 2) were characterized by elemental analysis, FT-IR, UV-visible, H-1, and C-13 NMR spectra. The molecular structure of the complex (2) was determined by single crystal X-ray diffraction technique. The structure consists of a distorted square-pyramidal geometry around the central metal, Zn(II). Quantum chemical calculations were carried out using density functional theory DFT/B3LYP, 6-31G (d), and LanL2DZ basis sets for theoretical characterization of the compounds. The experimental and theoretical data were compared comprehensively. The potential energy distribution (PED) analysis was performed for the assignment of vibration frequencies. In order to support in vitro studies, molecular docking studies have been carried out so that the title compound can be an inhibitor of Epidermal Growth Factor Receptor (1 m17), and the relationship between calculated HOMO energies and docking studies has been examined. In addition, the total antioxidant capacity (as TEAC value) and free radical scavenging activity of the compounds were determined by Cupric Reducing Antioxidant Capacity (CUPRAC) and 1,1-diphenyl-2-picryl hydrazyl (DPPH) methods, respectively. (C) 2021 Elsevier Ltd. All rights reserved.

Welcome to talk about 65-22-5, If you have any questions, you can contact Poladian, Q; Sahin, O; Karakurt, T; Ilhan-Ceylan, B; Kurt, Y or send Email.. Product Details of 65-22-5

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Product Details of 65-22-5. Authors Pishchugin, FV; Tuleberdiev, IT in MAIK NAUKA/INTERPERIODICA/SPRINGER published article about in [Pishchugin, F. V.; Tuleberdiev, I. T.] Kyrgyz Natl Acad Sci, Inst Chem & Phytotechnol, Bishkek 720071, Kyrgyzstan in 2021.0, Cited 13.0. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5

The kinetics and mechanism of condensation of pyridoxal hydrochloride with L-alpha-asparagine, L-alpha- and D-alpha-aspartic acids are analyzed via UV spectroscopy and polarimetry. It is found that L-alpha-asparagine containing alpha-NH2 and gamma-NH2 groups interacts with pyridoxal via the gamma-NH2 group, forming Schiff bases that are resistant to chemical transformations. Rearrangement produces Schiff bases that form the cyclic structure from the amino acid moiety. L-alpha- and D-alpha-aspartic acids interacting with pyridoxal via alpha-NH2 groups create Schiff bases that form quinoid structures after elimination of alpha-hydrogen or CO2. Their subsequent hydrolysis results in pyridoxamine, alpha-ketoacids, and aldehyde acids, respectively. Schemes of the condensation mechanisms of L-alpha-asparagine, L-alpha-, D-alpha-aspartic acids with pyridoxal hydrochloride are proposed.

Product Details of 65-22-5. Bye, fridends, I hope you can learn more about C8H10ClNO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Chemical synthesis of 5 ‘-beta-glycoconjugates of vitamin B-6 WOS:000519529400008 published article about PYRIDOXINE-BETA-GLUCOSIDE; PARTICULATE GLUCOSYLTRANSFERASE; PROTEIN GLYCOSYLATION; GROWING CULTURE; N-GLYCOSYLATION; FUSARIUM TOXINS; RICE BRAN; SEEDLINGS; GLUCURONIDATION; BIOAVAILABILITY in [Bachmann, Thomas; Schnurr, Christian; Zainer, Laura; Rychlik, Michael] Tech Univ Munich, Chair Analyt Food Chem, Maximus von Imhof Forum 2, D-85354 Freising Weihenstephan, Germany in 2020.0, Cited 107.0. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5. Product Details of 65-22-5

Various 5′-beta-saccharides of pyridoxine, namely the mannoside, galactoside, arabinoside, maltoside, cellobioside and glucuronide, were synthesized chemically according to KOENIGS-KNORR conditions using alpha 4,3-O-iso-propylidene pyridoxine and the respective acetobromo glycosyl donors with AgOTf (3.0 eq.) and NIS (3.0 eq.) as promoters at 0 degrees C. Furthermore, 5′-beta-[C-13(6)]-labeled pyridoxine glucoside (PNG) was prepared starting from [C-1(3)6]-glucose and pyridoxine. Additionally, two strategies were examined for the synthesis of 5′-beta-pyridoxal glucoside (PLG).

Product Details of 65-22-5. Welcome to talk about 65-22-5, If you have any questions, you can contact Bachmann, T; Schnurr, C; Zainer, L; Rychlik, M or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

SDS of cas: 65-22-5. Authors Zubenko, AA; Divaeva, LN; Morkovnik, AS; Fetisov, LN; Sochnev, VS; Kononenko, KN; Bodryakov, AN; Klimenko, AI in MAIK NAUKA/INTERPERIODICA/SPRINGER published article about in [Zubenko, A. A.; Fetisov, L. N.; Kononenko, K. N.; Bodryakov, A. N.; Klimenko, A. I.] Fed Rostov Agr Sci Ctr, North Caucasian Zonal Vet Res Inst, Novocherkassk 346406, Russia; [Divaeva, L. N.; Morkovnik, A. S.; Sochnev, V. S.] Southern Fed Univ, Inst Phys & Organ Chem, Rostov Na Donu 344090, Russia in 2020.0, Cited 29.0. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5

4-Hydroxymethyl-2-hetaryl(hetaroyl)furo[2,3-c]pyridines, the products of furan cyclization of pyridoxal with acylmethyl- and heteroarylmethyl halides, easily react with thionyl chloride in DMF to form new series of 4-chloromethyl-2-heteroaryl[2,3-c]pyridines. Further action of primary or secondary amines on these chloromethyl derivatives leads to the nucleophilic substitution of chlorine atoms with the formation of 4-aminomethyl-2-heteroaryl[2,3-c]pyridines. The study of anti-infective activity of the 4-RCH2-furo[2,3-c]pyridines (R = OH, Cl, (NRR2)-R-1) showed significant protistocidal and moderate antibacterial activity of some of representatives of these compounds.

SDS of cas: 65-22-5. Bye, fridends, I hope you can learn more about C8H10ClNO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Bal-Demirci, T; Guveli, S; Yesilyurt, S; Ozdemir, N; Ulkuseven, B in ELSEVIER SCIENCE SA published article about TRANSITION-METAL-COMPLEXES; X-RAY-STRUCTURE; PYRIDOXAL THIOSEMICARBAZONE; BIOLOGICAL-ACTIVITY; CRYSTAL-STRUCTURE; STRUCTURAL-CHARACTERIZATION; SPECTRAL CHARACTERIZATION; CATALYTIC APPLICATION; REDOX PROPERTIES; FREE-RADICALS in [Bal-Demirci, Tulay; Guveli, Sukriye; Ulkuseven, Bahri] Istanbul Univ Cerrahpasa, Engn Fac, TR-34320 Istanbul, Turkey; [Yesilyurt, Saffet] Maltepe Univ, Fac Engn & Nat Sci, TR-34857 Istanbul, Turkey; [Ozdemir, Namik] Ondokuz May S Univ, Fac Educ, Dept Math & Sci Educ, TR-55139 Samsun, Turkey in 2020.0, Cited 79.0. HPLC of Formula: C8H10ClNO3. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5

Mixed ligand nickel(II) and ruthenium(II) complexes were synthesized from pyridoxal-N-allyl-thiosemicarbazone hydrochloride and triphenylphosphine. The structures of the complexes have been characterized by elemental analysis, IR, H-1 and P-31 NMR, conductivity, magnetic moment measurements and single-crystal X-ray diffraction technique. Based on X-ray crystallographic studies, a square-planar structure has been proposed for the Ni(II) complex, in which the thiosemicarbazone ligand acts as dianionic tridentate ONS ligand. In the case of the Ru(II) complex, the thiosemicarbazone is coordinated to metal atom as a monoanionic bidentate NS donor ligand in an octahedral geometry. Antioxidant activities of the ligand and its metal complexes were calculated as their trolox equivalent antioxidant capacities (TEAC) by CUPRAC method and DPPH assay. Both the ligand and its metal complexes were found to be antioxidant and are much more antioxidant at least 2.1 times than trolox, even, ligand is 3.5 times greater than that of trolox according to CUPRAC. A linear correlation (correlation coefficient R-2 = 0.9997) appeared between the obtained TEAC values by the two antioxidant assays.

Bye, fridends, I hope you can learn more about C8H10ClNO3, If you have any questions, you can browse other blog as well. See you lster.. HPLC of Formula: C8H10ClNO3

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem