Application of 21717-95-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 21717-95-3, name is 2-Amino-3-fluoropyridine. This compound has unique chemical properties. The synthetic route is as follows.
A 25 -mL round-bottomed flask was charged with 3-fluoro-2- pyridinamine (1.0 g 8.9 mmol, Matrix Scientific, USA) and AcOH (10 mL). The reaction mixture was cooled to 0 C and NIS (2.0 g, 8.9 mmol, Sigma-Aldrich, India) was added in portions under a nitrogen atmosphere. The reaction mixture was warmed to room temperature and stirred for 5 h. The reaction mixture was diluted with cold water (30 mL), followed by a mixture of 5% Na2S203 (50 mL) and NaHC03 (100 mL) at room temperature. The solid that formed was collected via filtration, washed thoroughly with water and dried under reduced pressure at 40 C to give 3-f uoro-5-iodo-2-pyridinamine (2.0 g) as a white solid.
According to the analysis of related databases, 21717-95-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; AMGEN INC.; ASHTON, Kate; BOURBEAU, Matthew, Paul; HONG, Fang-Tsao; LIU, Longbin; NISHIMURA, Nobuko; NORMAN, Mark, H.; POON, Steve, F.; STEC, Markian, M.; ST. JEAN, David, J., JR; TAMAYO, Nuria, A.; YANG, Kevin, C.; WO2013/123444; (2013); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem