1-(4-Methoxyphenyl)-2-(6-methyl-2-nitro-3-pyridyloxy)propan-1-one was written by Vencato, Ivo;Ferri, Pedro H.;Santos, Suzana C.;Pereira, Maristela;Lariucci, Carlito;Homar, Leon I. B.;Napolitano, Hamilton B.. And the article was included in Acta Crystallographica, Section E: Structure Reports Online in 2005.Formula: C6H6N2O3 This article mentions the following:
The title compound, C16H16N2O5, is a β-ketoether derivative closely related to natural 8,4′-oxyneolignans, which are of interest because of their moderate antifungal activity against systemic mycosis. Crystallog. data are given. The nitro group is not coplanar with the aromatic ring, as shown by a torsion angle of 47.2(4)°. The mols. are linked by two nonclassical intermol. C-H···O H bonds with distances between donors and acceptors of 3.441(5) and 3.539(5) Å, giving mol. stacking perpendicular to the bc plane. In the experiment, the researchers used many compounds, for example, 3-Hydroxy-6-methyl-2-nitropyridine (cas: 15128-90-2Formula: C6H6N2O3).
3-Hydroxy-6-methyl-2-nitropyridine (cas: 15128-90-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Formula: C6H6N2O3