Accelerated decarboxylation of 1,3-dimethylorotic acid in ionic liquid was written by Wong, Freeman M.;Wu, Weiming. And the article was included in Bioorganic Chemistry in 2006.Computed Properties of C7H7NO3 This article mentions the following:
The solvent effect of ionic liquids on the decarboxylation of 1,3-dimethylorotic acid and its analog in ionic was investigated. The rate acceleration observed was proposed to be a result of the stabilization of the zwitterionic intermediates by the charged groups available in these special solvents. In the experiment, the researchers used many compounds, for example, 1-Methyl-6-oxo-1,6-dihydropyridine-2-carboxylic acid (cas: 59864-31-2Computed Properties of C7H7NO3).
1-Methyl-6-oxo-1,6-dihydropyridine-2-carboxylic acid (cas: 59864-31-2) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Computed Properties of C7H7NO3