Synthesis of E-resveratrol in commercial scale production was written by Yang, Jie;Zhang, Ya-lu;Zhou, Zhi-xu;Sun, Tie-min. And the article was included in Zhongnan Yaoxue in 2015.SDS of cas: 628-13-7 This article mentions the following:
Objective: To study the synthesis of E-resveratrol from the view of com. scale production Methods: The target compound was prepared from 3,5-dihydroxy benzoic acid by methylation and reduction, followed by chloro-substituted and Arbuzov rearrangement reaction with tri-Et phosphate, then condensation with anisaldehyde and demethylation with pyridine hydrochloride. Results: The overall yield of this method was 52.0%. The purity of E-resveratrol was 98.54%. Conclusion: The improved procedure could be easily operated and was suitable for scale production In addition, the starting materials were conveniently obtained. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7SDS of cas: 628-13-7).
Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. SDS of cas: 628-13-7