Studies on new reactions of pyridine-copper chloride complex was written by Zeng, Xian-Mou;Chen, Xi-Wen;Xu, Ren-Xian;Sun, Yun-Song;Yu, Shu-Wen;Guo, Lian-Ying;Cheng, Guo-Bao;Gu, Yi-Jian. And the article was included in Scientia Sinica (English Edition) in 1981.Reference of 644-98-4 This article mentions the following:
Cu(py)2Cl2 undergoes alkylation at the γ- and α-positions of the pyridine ligands upon reaction with alkyl halides in the presence of Na under mild conditions. The products are decomposed by alkali to give the α- and γ-alkylpyridines in <40% yields. The γ-alkylpyridines are the main products. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Reference of 644-98-4).
2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Reference of 644-98-4