Practical Method for Reductive Deuteration of Ketones with Magnesium and D2O was written by Zhu, Nengbo;Su, Min;Wan, Wen-Ming;Li, Yajun;Bao, Hongli. And the article was included in Organic Letters in 2020.HPLC of Formula: 91-02-1 This article mentions the following:
α-Deuterated diarylmethanols such as Ph2CD(OH) were prepared chemoselectively and with 72->99% deuteration by reductive deuteration of diaryl ketones such as benzophenone with Mg, BrCH2CH2Br, and D2O in THF at 70°. The method was used to prepare deuterated analogs of fenofibrate, diphenhydramine, and buclizine and precursors to deuterated modafinil and adrafinil. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1HPLC of Formula: 91-02-1).
Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.HPLC of Formula: 91-02-1